Showing titles in History & Commentary

Ignác Semmelweis is remembered for the now-commonplace notion that doctors must wash their hands before examining patients. In mid-19th century Vienna, however, this was a subversive idea. With deaths from childbed fever exploding, Semmelweis discovered that doctors themselves were spreading the disease. While his simple reforms worked immediately - childbed fever in Vienna all but disappeared - they brought down upon Semmelweis the wrath of the establishment, and led to his tragic end.

The plague that devastated Asia and Europe in the 14th century has been of never-ending interest to both scholars and the general public. Many books on the plague rely on statistics to tell the story. In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

We all know the history of science that we learned from grade school textbooks: how Galileo used his telescope to show that the earth was not the center of the universe; how Newton divined gravity from the falling apple; how Einstein unlocked the mysteries of time and space with a simple equation. This history is made up of long periods of ignorance and confusion, punctuated once an age by a brilliant thinker who puts it all together. These few tower over the ordinary masses, and in the traditional account, it is to them that we owe science in its entirety. This belief is wrong.

For centuries, medicine has made reckless use of one of earth's most toxic substances: mercury - and the consequences, often invisible or ignored, continue to be tragic. Today, global emissions of mercury as well as other toxicants, make us all more vulnerable to its effects. From the worst cases of syphilis to Sigmund Freud's first cases of hysteria, from baffling new disorders in 19th century Britain to the modern scourge of autism, The Age of Autism traces the long overlooked history of mercury poisoning.

In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease

Until the 1970s, if you suffered a medical crisis, your chances of survival were minimal. A 9-1-1 call might bring police or even the local funeral home. But that all changed with Freedom House EMS in Pittsburgh, a group of Black men who became America’s first paramedics and set the gold standard for emergency medicine around the world, only to have their story and their legacy erased—until now.

In the spring of 1812, Napoleon Bonaparte was at the height of his powers. Forty-five million called him emperor, and he commanded a nation that was the richest, most cultured, and advanced on earth. No army could stand against his impeccably trained, brilliantly led forces, and his continued sweep across Europe seemed inevitable.

Over the past 50 years, rates of autoimmunity and chronic disease have exploded. In this provocative book, Dr. Thomas Cowan argues for a direct causal relationship to a corresponding increase in the number of vaccines American children typically receive. The goal of these vaccines is precisely what we’re now seeing in such abundance among our chronically ill children: the provocation of immune response. Cowan looks at emerging evidence that certain childhood illnesses are actually protective of disease later in life.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

Martin Arrowsmith is fascinated by science and medicine. As a boy, he immerses himself in Gray’s Anatomy. In medical school, he soaks up knowledge from his mentor, a renowned bacteriologist. But soon he is urged to focus on politics and promotions rather than his research. Even as Martin progresses from doctor to public health official and noted pathologist, he still yearns to devote his time to pure science.

A decade after World War II, there was still no such thing as open-heart surgery, and yet half a million Americans were dying from heart disease every year. After the first daring operation in 1954 and through the next three decades, five heroic surgeons braved the scorn of their peers, withstood fierce desperation, and faced possible death in order to devise procedures that would save overwhelming numbers of those doomed children and provide hope for a new life to all manner of heart-failing individuals.

In 1930s and 1940s Vienna, child psychiatrist Hans Asperger sought to define autism as a diagnostic category, aiming to treat those children, usually boys, he deemed capable of participating fully in society. Depicted as a compassionate and devoted researcher, Asperger was in fact deeply influenced by Nazi psychiatry. Although he did offer individualized care to children he deemed promising, he also prescribed harsh institutionalization and even transfer to Spiegelgrund for children with greater disabilities, who, he held, could not integrate into the community.

The harrowing, dramatic and profoundly moving story of the Australian and New Zealand nurses who served in the Great War. Now a major six-part television series. By the end of the Great War, 45 Australian and New Zealand nurses had died on overseas service and over 200 had been decorated. These were the women who left for war looking for adventure and romance but were soon confronted with challenges for which their civilian lives could never have prepared them.

In January 1918, as World War I raged on, a new and terrifying virus began to spread across the globe. In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but worldwide, the pandemic gained the notorious title of “Spanish flu”. Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war) while European deaths totaled more than two million.

Its landscaped ground, chosen by Frederick Law Olmsted and dotted with Tudor mansions, could belong to a New England prep school. There are no fences, no guards, no locked gates. But McLean Hospital is a mental institution - one of the most famous, most elite, and once most luxurious in America. Gracefully Insane, by Boston Globe columnist Alex Beam, is a fascinating and emotional biography of McLean Hospital from its founding in 1817 through today.

Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively listenable Superbugs, and the results will impact nothing less than the future of humanity.

Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception―a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. His book is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk untried new therapies.

In the mid 1980s, Canada's worst public health disaster was unfolding. Catastrophic mismanagement of the country's blood supply allowed contaminated blood to be knowingly distributed, infecting close to two thousand Canadians with HIV. Among them was Melanie Brooks's surgeon father who, after receiving a blood transfusion during open-heart surgery in 1985, learned he was HIV positive. At a time when HIV/AIDS was misunderstood and public perception was shaped by fear, prejudice, and homophobia, victims of the disease faced ostracism and persecution. Wanting to protect his family from this stigma, Melanie's father decided his illness would be a secret they'd all keep.

Following the trail of an unexpected family connection, acclaimed journalist Pam Fessler has unearthed the lost world of the patients, nurses, doctors, and researchers at Carville who struggled for over a century to eradicate Hansen's disease, the modern name for leprosy. Amid widespread public anxiety about foreign contamination and contagion, patients were deprived of basic rights - denied the right to vote, restricted from leaving Carville, and often forbidden from contact with their own parents or children.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.