The Ageless Brain

How to Sharpen and Protect Your Mind for a Lifetime

By: Dale E. Bredesen MD

Narrated by: Robert Petkoff

From the bestselling author of The End of Alzheimer’s, Dr. Dale Bredesen, comes a revolutionary new approach to preventing the onset of neurodegenerative disease and creating sustained brain health.

In recent decades, advances in medicine have changed the way we think about our health. Chronic diseases like obesity, heart disease, and diabetes can be prevented or reversed. Cancer treatment has become targeted and personalized. Gene editing will allow us to eradicate many inherited disorders. But there is one class of conditions that continues to elude researchers and cause tremendous suffering: neurodegenerative disease.

More than six million Americans live with Alzheimer’s disease; by 2050, this number is projected to reach thirteen million. An additional one in ten people over the age of sixty-five have dementia, while 22 percent of older adults live with some form of cognitive impairment. And it isn’t just the elderly who are afflicted; diagnosis rates are rising in younger adults, with women at a higher risk than men. For many—especially those with a genetic predisposition—this fate has seemed inevitable. Until now.

Dr. Dale Bredesen is a pioneer in the field of neurodegenerative research. Lauded for his integrative protocol, he has, in clinical studies, reversed the symptoms of Alzheimer’s and dementia. He shared this information in his bestselling book, The End of Alzheimer’s. But Dr. Bredesen doesn’t want to only treat the symptoms of this devastating illness. He wants to prevent it from developing in the first place.

In The Ageless Brain, Dr. Bredesen will share the latest, cutting-edge science on neurodegeneration, including how misunderstandings of the disease have hindered our efforts to treat it, as well as a preventative program that listeners of all ages can put into practice to optimize their cognitive health now and sustain it for years to come. This is an audiobook for everyone who cares about their ability to stay sharp and independent for a lifetime, for those who have witnessed family members decline, and for the many listeners who are beginning to experience moments of brain fog or fatigue in middle age, and are concerned about what the future may hold.

Just as bestselling authors like Dr. Peter Attia and Dr. Michael Greger have offered essential guidance for maintaining overall health and longevity, Dr. Bredesen has written the only book you need to retain your vibrant mind—and thrive for a lifetime.

A Macmillan Audio production from Flatiron Books.

PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.

©2025 Dale E. Bredesen (P)2025 Macmillan Audio

Critic reviews

“For far too long, we’ve been led to believe that keeping a sharp mind and a strong memory is beyond our control. Dr. Dale Bredesen’s groundbreaking work proves otherwise. The Ageless Brain is a practical and inspiring guide that equips readers with essential knowledge to combat the most debilitating effects of aging. As a global leader in cognitive decline and brain degeneration, Dr. Bredesen gifts us with the tools and insights needed to support lifelong brain health. For everyone, this book is essential.”—David Perlmutter, MD, FACN, #1 New York Times bestselling author of Grain Brain and Drop Acid

“Dale Bredesen is at the forefront of research on cognitive decline and neurodegeneration. With The Ageless Brain, he arms readers with the essential information they need to avoid some of the most debilitating effects of aging. And it’s never too early to get started. If you have a brain—and you want to protect it—you need to read this book.”—Terry Wahls, MD, bestselling author of The Wahls Protocol

“Dr. Dale Bredesen is a world-class neuroscientist/neurologist who through his innovative and exacting research has discovered a safe and effective approach to the prevention and treatment of Alzheimer’s disease that will revolutionize the way we think about the disease.”—Jeffrey S. Bland, PhD, FACN, FACB, bestselling author of The Disease Delusion

Great book

very comprehensive, science based and practical. highly recommend for anyone who want longevity with sound mind

Facts n studies

Details about research. Confidence of what's to come. Keeps you humble with what you have. You can start now rather than waiting for tomorrow!

Actionable items and hope

This narrator was excellent and it seemed that he was so heavily invested in the narrative, I wondered if he was the author! For he isn't!

Not what I expected

I thought the book was going to have more information on what we could do ourselves. I was confused in chapter 14 where he speaks of a woman in her mid thirties who begins doing things to improve her brain. He speaks of her using a wearable to track her sleep. As the book progresses he is talking about the woman being in her 90s. How is she using wearables before they were invented? Maybe I missed something.

A must read for every young person.

This book was very easy to understand, and it kept my interest throughout. Great guidance on how we can make changes now, to avoid cognitive decline later.

Scary, but hopeful

I never heard the “Recode” protocol in a concise manner. I personally disagree that red meat is to be limited.

Brain health interventions

Speech clear and paced so easy to understand ! Numerous supplements, mental health and physical activity discussed ..

Don’t buy this book!!

The author is a master in bloviation. The book could have been 1/2 the size and still too long. A little valuable info surrounded by so much talk!!

Totally unrealistic

The recommendations he makes are completely unrealistic for an average American. You would have to shoot your own game and farm your own food to make this affordable. It would be a full time job.