Lifespan
Why We Age - and Why We Don't Have To
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Narrated by:
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David A. Sinclair PhD
About this listen
Audio bonus! Includes exclusive conversations with the authors!
From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.
For decades, experts have believed that we are at the mercy of our genes and that natural damage to our genes - the kind that inevitably happens as we get older - makes us become sick and grow old.
But what if everything you think you know about aging is wrong? What if aging is a disease - and that disease is treatable?
In Lifespan, one of the world’s foremost experts on aging and genetics reveals a groundbreaking new theory that will forever change the way we think about why we age and what we can do about it. Aging isn’t immutable; we can have far more control over it than we realize. This eye-opening and provocative work takes us to the front lines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs - many from Dr. David Sinclair’s own lab - that demonstrate how we can slow down, or even reverse, the genetic clock. The key is activating newly discovered vitality genes - the decedents of an ancient survival circuit that is both the cause of aging and the key to reversing it. Dr. Sinclair shares the emerging technologies and simple lifestyle changes - such as intermittent fasting, cold exposure, and exercising with the right intensity - that have been shown to help lead to longer lives.
Lifespan provides a road map for taking charge of our own health destiny and a bold new vision for the future when humankind is able to live to be 100 years young.
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2019 David Sinclair (P)2019 Simon & Schuster AudioListeners also enjoyed...
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- Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection
- By: Sam Apple
- Narrated by: Mark Bramhall
- Length: 12 hrs and 58 mins
- Unabridged
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The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.
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Highly recommended, a must read.
- By Joerg on 06-10-21
By: Sam Apple
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Denialism
- How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives
- By: Michael Specter
- Narrated by: Richard Poe
- Length: 8 hrs and 33 mins
- Unabridged
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Overall
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New Yorker staff writer Michael Specter has twice won the Global Health Council’s Excellence in Media Award, as well as the Science Journalism Award from the American Association for the Advancement of Science. In Denialism, he fervently argues that people are turning away from new technologies and engaging in a kind of magical thinking that is hindering scientific progress.
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A compelling read
- By S on 05-17-11
By: Michael Specter
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- By: Francis S. Collins
- Narrated by: Greg Itzin
- Length: 10 hrs and 45 mins
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Overall
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Performance
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A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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The future of medicine
- By Ronald E on 04-12-10
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
- Unabridged
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
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Pandora's Seed
- The Unforeseen Cost of Civilization
- By: Spencer Wells
- Narrated by: Spencer Wells
- Length: 6 hrs and 40 mins
- Unabridged
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This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.
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Short and unfocused, but often quite interesting.
- By Alan on 06-23-10
By: Spencer Wells
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
- Unabridged
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Overall
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Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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The Truth About Cancer
- By: Ty M. Bollinger
- Narrated by: Ty M. Bollinger
- Length: 9 hrs and 11 mins
- Unabridged
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One out of three women alive today, and one out of two men, will face a cancer diagnosis, according to the World Health Organization. Ty Bollinger takes this personally: in the course of a decade, he says, "I lost my entire family to cancer. I don't believe I had to lose them." The Truth about Cancer has been written for one simple reason: to share the knowledge we need to protect ourselves, treat ourselves, and in some cases save our lives or the lives of those we love.
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save a life with this valuable information.
- By edwin matias on 12-30-16
By: Ty M. Bollinger
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The Story of the Human Body
- Evolution, Health, and Disease
- By: Daniel Lieberman
- Narrated by: Sean Runnette
- Length: 14 hrs and 54 mins
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In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.
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Could Have Been Good, but...
- By Trebla on 04-08-18
By: Daniel Lieberman
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- By: Leonardo Trasande MD MPP
- Narrated by: Leonardo Trasande MD MPP
- Length: 6 hrs and 44 mins
- Unabridged
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Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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The Must Read Book of 2019 is here early on Audio!
- By Ryan S on 12-21-18
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Editing Humanity
- The CRISPR Revolution and the New Era of Genome Editing
- By: Kevin Davies
- Narrated by: Kevin Davies
- Length: 16 hrs and 17 mins
- Unabridged
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Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.
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Excellent content, solid execution
- By Samuel Finlayson on 01-25-21
By: Kevin Davies
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What listeners say about Lifespan
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Mark C. Manderson
- 04-27-22
The science of aging
I enjoyed this book. Here are my takeaways.
Minimize meat, dairy, and sugar
Eat vegetables and legumes.
Eat 25% less calories to live longer.
Always leave the table wanting more.
HIIT training helps trigger longevity genes.
Cold exposure helps trigger longevity genes.
Metaformin and MNM helps with anti aging.
Resveratrol also helps expanding life span.
WAYS TO ADD 10% TO LIFE:
CONSUME FEWER CALORIES
WORKOUT WHERE HEART RATE IS UP
EAT LESS AMINOS FOUND IN ANIMAL MEAT
SPEND TIME DAILY OUTSIDE YOUR NEUTRAL THERMAL CLIMATE ZONES.
HIS REGIMEN:
- MNM 1 Gram daily
- NAT
- METAFORMIN 1 gram
- ASPIRIN 83mg
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- MJ
- 10-10-20
Politics Out Please
I would’ve given this five stars if not for the political inclusion. Not appropriate and reduces the validity of the genius work behind what the research presented.
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7 people found this helpful
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- pgote3
- 10-23-19
got political
too political for my blood. looking for a more scientific approach. Started good, but soon went anti Trump.
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7 people found this helpful
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- Anonymous User
- 01-13-20
Myopic
Science was interesting. Ethics were dubious and myopic. Had the author focused on the scientific breakthroughs on the horizon, and left the reader to draw his/her own conclusions rather than force-feeding his views on the ethical implications involved, would have been a great book. Just got really annoying for most of the second half of the book.
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4 people found this helpful
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- Bart Binning
- 11-04-19
Extending life: Current leading edge of knowledge
A fascinating book describing the current knowledge base of research to extend the human lifespan. A technical book that is surprisingly easy for the interested lay person to read; full of “off the shelf” things that the average person can do to increase their quality of life and extend their lifespan.
The last 1/4 in the book is mostly pontification on how to change the world.
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- Amazon Customer
- 09-17-20
First half was 5 stars, then...
The science part was fascinating, then he goes off into anecdotal evidence that sound a bit like optimistic stories. I would have been happy with that being it, but then he jumps off the proverbial political cliff and it kills what would have been a wonderful 5 star, science based book.
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- Jeffrey
- 09-18-19
This Should be Required Reading!
This is such an exciting book! You just have to read it. There is so much to grasp. Even so, it is presented in a manner that even those without a science or biological background can easily comprehend. Honest!
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- Rob
- 02-23-20
Exceptional until it's Not
The book is amazing when he's talking about the ground breaking research from his lab. Wow, I learned a lot! But the Section 3 got into his opinions about the implications. They might be correct, but he's no expert in this area. I found myself wishing the book had ended hours earlier.
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- xesus
- 10-29-19
Iteresting listen
I expected it to be more scientifically informative and less story telling. Was interesting to listen anyway, Guess easier for general public. I felt that some scientific details were skipped
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- AR
- 11-26-21
first 5 chapters are groundbreaking
then he becomes political and gets really into creating a large and populous world.
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1 person found this helpful