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Over the last decade, scientists have discovered the importance and widespread presence in the body of a remarkable family of proteins known as prion proteins. Research links various types of prion proteins to neurodegenerative diseases such as Parkinson's and Alzheimer's—and this has fueled the search for new drugs that could halt the progression of these terrible disorders. Other discoveries have revealed the essential roles prion proteins play in memory and immunity, and the part they may have played in the beginnings of life on our planet.

Music, Lyrics, and Life is the songwriting class you always wish you'd taken, taught by the professor you always wish you'd had. It's a deep dive into the heart of questions asked by songwriters of all levels, from how to begin journaling to when you know that a song is finished. With humor and empathy, acclaimed singer-songwriter Mike Errico unravels both the mystery of songwriting and the logistics of life as a songwriter.

Experience the dramatic life-changing power of God's Holy Word on the go. This dramatic, multi-voice recording with original orchestral music and sound effects brings the major Bible themes and stories alive.

Do you HATE public speaking? Are you TERRIFIED to stand in front of people? When you think of speaking, do you get nervous, anxious, even sweaty? You don’t have to be afraid any longer. It can seem like everyone is a gifted speak when you watch TED talks or compare yourself to skilled co-workers giving presentations. Don't get caught up in comparison. Instead, take action to improve YOUR ability and to overcome your fear. If you struggle when you speak, then you are not alone. Public speaking is the number one fear in America.

This comprehensive record of Krishnamurti’s teachings is an excellent, wide-ranging introduction to the great philosopher’s thought. With among others, Jacob Needleman, Alain Naude, and Swami Venkatasananda, Krishnamurti examines such issues as the role of the teacher and tradition; the need for awareness of ‘cosmic consciousness; the problem of good and evil; and traditional Vedanta methods of help for different levels of seekers.

Online, influencer Abby Allerton is savvy, relevant, and empowered due to her Instagram profiles Plus-Size Real and Femme Fatale, but IRL not so much—she’s sadly stagnant and in need of an upgrade. When the #BTSPFW invite drops into her inbox, Abby can’t help but say, “Oui, oui, this is for me!” and do whatever it takes to get on the next plane to Paris for an exclusive behind-the-scenes Fashion Week event!

"Perhaps God isn't giving me the plan because He wants to be the plan." This was the aha moment for Mike Donehey after years of wrestling with his obsession to know God's specific plans for his life. He came to the realization that waiting for absolute certainty from God before making decisions may seem uberspiritual, but it can lead to a life of intense stress, paralyzing fear, and crushing regret - just the opposite of the freedom granted to those living a Christ-filled life.

You can use this book to design a house for yourself with your family; you can use it to work with your neighbors to improve your town and neighborhood; you can use it to design an office, a workshop, or a public building. And you can use it to guide you in the actual process of construction.

A guy who rejects or breaks up with you should no longer exist in your life. Contacting him or allowing him to stay in touch with you will make you work harder and harder to convince him that you’re worth his love and attention, and it will compel you to play that ugly and unwinnable game called Chase-a-Man. The best way to avoid this ugly game and break his spell over you is to cut the guy off (cease all communications and interactions) for a set period of time, or in some cases, keep him cut off out of your life indefinitely.

Much more than a response to harm, restorative justice nurtures relational, interconnected school cultures. The wisdom embedded within its principles and practices is being welcomed at a time when exclusionary discipline and zero-tolerance policies are recognized as perpetuating student apathy, disproportionality, and the school-to-prison pipeline.

If you're like most entrepreneurs, you started your company so you could be your own boss, make the money you deserve, and live life on your own terms. In reality, you're bogged down in the daily grind, constantly putting out fires, answering an endless stream of questions, and continually hunting for cash.

In Built to Finish, Steven Pivnik takes you on two journeys: leading his software and services company, Binary Tree, from inception to successful exit and his quest to compete in the IRONMAN® World Championship in Kona, Hawaii. Steven shares how the insights gained from his adventures in triathlon, mountaineering, and ultramarathons apply to anyone’s pursuit of long-term personal and professional success.

What if you could have whatever you want, produced and provided immediately and affordably no matter how customized—with minimal environmental impact? Products, services, and experiences on demand. Just-in-time anything, anywhere, anytime. This radical change is underway, as digital technologies push the production and provision of value ever closer to the moment of demand. Robert C. Wolcott and Kaihan Krippendorff provide an indispensable guide to the Proximity revolution, showing how it's transforming every industry—and our lives.

William C. Martin has freshly reinterpreted the Tao Te Ching to speak directly and clearly to the most difficult of modern tasks—parenting. With its combination of free verse and judicious advice, The Parent's Tao Te Ching addresses the great themes that permeate the Tao and that support loving parent-child relationships: responding without judgment, emulating natural processes, and balancing between doing and being.

Filled with stories of those who have walked the path of deconstruction without losing their faith, Invisible Jesus: A Book about Leaving the Church and Looking for Christ by Scot McKnight with Tommy Phillips is a prophetic call to discern if the faith we practice and the church we belong to is representative of the Jesus we follow.

When a tiny island--a jewel on the breast of the broad Pacific--becomes a maniac's murder laboratory, the serene beauty of Mauilei is shattered by a series of gruesome killings. The body of Grant, a skilled rider, is found with a bloated, bruised neck and a terrifying expression frozen on his face. As the plantation manager, Rice Lauder, and his team grapple with the horror, they uncover a chilling pattern of violence and madness.

How well does your organization respond to changing market conditions, customer needs, and emerging technologies when building software-based products? This practical guide presents Lean and Agile principles and patterns to help you move fast at scale - and demonstrates why and how to apply these methodologies throughout your organization. Through case studies, you'll learn how successful enterprises have rethought everything from governance and financial management to systems architecture and organizational culture in the pursuit of radically improved performance.

Ripped from the man I’m bound to. Thrust into fresh danger. And this time I must go alone. Except the task I’m burdened with should belong to a more powerful fae—my mother. Listening to her brought me to this moment of heartache and loss. Perhaps the time has come for a new approach, no matter the consequences.

When Seckry was six years old, his father disappeared. The two of them had spent the afternoon picking berries together in the fields surrounding their village. In Seckry's vague memory, it had been perfect. But the following morning his father was gone, and had taken all traces of his existence with him. Dreams of that afternoon still plague Seckry's nights. Swimming in and out of his consciousness are images of his father's watch; one that was glowing an eerie green, and inscribed with foreign markings. What had his dad told him about that watch?

Absinthe, an elixir made of alcohol and herbs, is a booming business. Yet it is still an underground culture, associated with mystery, romance, and bohemian lifestyles, in keeping with its popularity among the writers, artists, and other ne'er-do-wells. First produced in eighteenth century, the spirit, known as "the Green Fairy," was banned worldwide by 1914 before the bans were gradually overturned beginning in 2005, the year Switzerland relegalized absinthe.