Showing titles in Genetics

Biology is undergoing a quiet but profound transformation. Several aspects of the standard picture of how life works—the idea of the genome as a blueprint, of genes as instructions for building an organism, of proteins as precisely tailored molecular machines, of cells as entities with fixed identities, and more—have been exposed as incomplete, misleading, or wrong. In How Life Works, Philip Ball explores the new biology, revealing life to be a far richer, more ingenious affair than we had guessed.

DEL AUTOR DEL BESTSELLER "LA VIDA EN CUATRO LETRAS". "El sueño del tiempo" surge de la constatación de que, aunque la física y la filosofía nos enseñan que el flujo del tiempo puede ser solo una fantasía creada por nuestra mente, el tiempo biológico vive en nosotros y nosotros vivimos en el tiempo del mundo.

A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.

This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is for every one of the 100 billion modern humans who has ever drawn breath. But it is also our collective story, because in each of our genomes we carry the history of the whole of our species.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

In November 1987, a young couple on an overnight trip to Seattle vanished without a trace. A week later, the bodies of Tanya Van Cuylenborg and her boyfriend Jay Cook were found in rural Washington. It was a brutal crime, and it was the perfect crime: With few clues and no witnesses, an international manhunt turned up empty, and the sensational case that shocked the Pacific Northwest gradually slipped from the headlines.

On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich.

Vital research is starting to challenge long-standing assumptions about gender identity and biological sex, such as work that indicates the brain is a “mosaic” of traits rather than a “male” and “female” brain. Growing knowledge of the genetic complexities of sexual determination is changing the way the medical community treats intersex individuals, and in this audiobook, The New Science of Sex and Gender, we not only examine the latest studies in biology, medicine, and psychology but also, more importantly, their bearing on healthcare, identity, and access.

This paradigm-shifting book paints a spirited portrait of a restless people that challenges our established ways of looking at Europe's past. The story is more complex than at first believed, with new evidence suggesting that the European gene pool was stirred vigorously multiple times. Genetic clues are also enhancing our understanding of European mobility in epochs with written records, including the arrival of the Anglo-Saxons, the spread of the Slavs, and the adventures of the Vikings.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no-one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In Lifespan, Dr David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that.

From New York Times best-selling author Sam Kean come more incredible stories of science, history, language, and music, as told by our own DNA. There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

Growing up in California, J. Craig Venter didn't appear to have much of a future. An unremarkable student, he nearly flunked out of high school. After being drafted into the army, he enlisted in the Navy and went to Vietnam, where the life-and-death struggles he encountered as a medic piqued his interest in science and medicine. After pursuing his advanced degrees, Venter quickly established himself as a brilliant and outspoken scientist.

Con el descubrimiento del ADN –el elemento básico de la vida– Crick y Watson influyeron en el desarrollo de la humanidad no solo en el ámbito científico, con la clonación y la investigación médica, sino también en nuestra vida diaria con la manipulación genética de los alimentos o la medicina forense. El descubrimiento del ADN también ha provocado serios dilemas éticos.

Partiendo de un momento extraordinariamente difícil de la vida del autor, este audiolibro empieza con una pregunta fascinante: ¿llevamos la felicidad escrita en nuestros genes? Tomando esta pregunta como hilo conductor a lo largo de 14 capítulos, López-Otín nos presenta los momentos estelares de la historia de la vida sobre la Tierra, nos explica cómo llegamos hasta aquí y por qué una serie de adversidades nos trajo la enfermedad como amenaza universal contra la felicidad.

Psychiatric Pharmacogenetics is a book written by a physician and scientist - both renowned in the field of psychiatric pharmacogenetics - and written specifically for the busy practitioner. It gives a synopsis of the history of how the science of pharmacogenetics evolved, and gives a basic but detailed overview of the science which is rooted in the Cytochrome P450 system.

The DNA Restart, by world-renowned neurogeneticist and New York Times best-selling author Dr. Sharon Moalem, walks you through revolutionary steps to a diet and lifestyle perfect for your individual genetic makeup. The DNA Restart plan utilizes decades of in-depth scientific research into genetics, epigenetics, nutrition, and longevity to explain the pivotal role genes play in the journey to ideal weight and health status.

In Faster, Higher, Stronger, veteran journalist Mark McClusky brings listeners behind the scenes with a new generation of athletes, coaches, and scientists whose accomplishments are changing our understanding of human physical achievement and completely redefining the limits of the human body.

In Food, Genes, and Culture, renowned ethnobotanist Gary Nabhan shows why the perfect diet for one person could be disastrous for another. If your ancestors were herders in Northern Europe, milk might well provide you with important nutrients, whereas if you’re Native American, you have a higher likelihood of lactose intolerance. If your roots lie in the Greek islands, the acclaimed Mediterranean diet might save your heart; if not, all that olive oil could just give you stomach cramps.