West Wellness and Longevity Links

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Today, we delve into the intricacies of a novel peptide known as Retatrutide, a compound currently undergoing stage three clinical trials overseen by the FDA and developed by Eli Lilly. This peptide distinguishes itself by functioning as a triple agonist, selectively targeting three critical receptors: GLP1, GIP, and glucagon. The unique mechanism of action of Retatrutide not only aims to regulate blood sugar levels but also to suppress appetite and enhance energy expenditure, thereby presenting a promising therapeutic avenue for managing weight loss and diabetes. Preliminary findings indicate that participants in clinical trials have experienced substantial weight reduction, averaging 24.2% over 48 weeks at the highest dosage. As we explore the multifaceted benefits and potential applications of Retatrutide, we also reflect on the broader implications for individuals struggling with insulin resistance and weight management.

Takeaways:

• The peptide known as Retatrutide, scientifically referred to as LY3437943, is currently undergoing stage three clinical trials under the auspices of the FDA and is developed by Eli Lilly.
• Retatrutide functions as a triple agonist, effectively targeting three distinct receptors, namely GLP1, GIP, and glucagon, which together facilitate the management of blood sugar levels and appetite suppression.
• Clinical studies reveal that individuals administered the highest dosage of Retatrutide achieved an impressive average weight loss of approximately 24.2% over a span of 48 weeks, making it a promising option for obesity management.
• The unique mechanism of Retatrutide distinguishes it from existing treatments, as it simultaneously addresses metabolic and hormonal pathways, presenting a multifaceted approach to weight management and glycemic control.
• The anticipated completion of clinical trials for Retatrutide is projected around February 2026, although market availability may extend to 2027, indicating a significant wait for potential users.
• It is imperative that individuals considering the use of Retatrutide engage with a licensed healthcare practitioner to ensure proper guidance and monitoring throughout the treatment process.

Links referenced in this episode:

• westwellnessatx

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

Methylation emerges as a pivotal biochemical process that profoundly influences various physiological functions, including detoxification, mood regulation, and energy production. In our discussion, we elucidate the significance of methylation, particularly in light of the fact that a substantial portion of the population—estimated at around 40%—possesses genetic variants that may adversely affect this essential process. Drawing from personal experiences and clinical observations, I highlight how disruptions in methylation can manifest as fatigue, mood swings, and chronic inflammation. Furthermore, we explore the intricate relationship between methylation and hormonal balance, particularly concerning estrogen and testosterone metabolism, underscoring the potential implications for overall health. Through this episode, we aim to provide listeners with a comprehensive understanding of methylation, its critical roles, and actionable strategies for optimization to enhance well-being.

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

Non- Toxic Cookware:https://www.greenpan.us/WESTWELLNESSATX

Non-Toxic Cleaners/detergents: https://shareasale.com/r.cfm?b=1736653&u=4252226&m=108208&urllink=&afftrack=

Non-Toxic Face/ body products: https: https://amzn.to/3ExhwZf

Non-Toxic Food Storage: https://amzn.to/4hFtezx

EWG: https://www.ewg.org/

The crux of today's discourse centers on the pervasive issue of hormone dysregulation, a phenomenon that is alarmingly affecting the health of young men and women, particularly within the United States. This episode elucidates the significant role of endocrine disruptors—ubiquitous chemicals present in various everyday products, including plastics, food packaging, and personal care items—that interfere with natural hormone functions. These disruptors contribute to the alarming trends of declining testosterone levels, fertility issues, and conditions such as polycystic ovary syndrome (PCOS) and insulin resistance. We delve into the scientific underpinnings of these endocrine disruptors, examining their origins and the mechanisms by which they precipitate metabolic dysfunction and chronic diseases. Ultimately, we advocate for informed lifestyle choices and dietary modifications to mitigate exposure to these harmful substances and promote hormonal health.

Studies and Research Referenced:

Ultra-Processed Foods Intake and Sex Hormone Levels Among Adolescents: This study found that UPF consumption is associated with increased exposure to endocrine disruptors (EDCs), such as phthalates and bisphenols, which are known to interfere with the body's hormonal balance.

pmc.ncbi.nlm.nih.gov

Ultra-Processed and Fast Food Consumption, Exposure to Phthalates During Pregnancy: This study found that consuming ultra-processed foods may increase exposure to phthalates, a group of endocrine disruptors prevalent in food contact materials.

pmc.ncbi.nlm.nih.gov

Study Finds Widespread Exposure to Hormone-Disrupting Chemical During Pregnancy: Research from Rutgers University indicates that diets higher in ultra-processed foods are associated with increased concentrations of zearalenone (ZEN), a mycoestrogen that mimics estrogen in the body.

rutgers.edu

The Connection Between Ultra-Processed Foods and Endocrine Disruptors: This article examines how UPFs often contain additives and contaminants that act as endocrine disruptors. It discusses the potential mechanisms by which these substances contribute to obesity and metabolic disorders through hormonal imbalances.

stop.publichealth.gwu.edu

Hormone-Disrupting Chemicals Found in Popular US Fast Foods: A study detected phthalates, a class of EDCs, in popular fast-food items. For instance, Wendy's crispy chicken nuggets,...

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Get your own GHK-Cu Peptide here:https://www.vitaliskincare.com/?ref=undrarql
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

Peptides are a fascinating topic that can significantly impact health, longevity, and wellness. They are short chains of amino acids that act as signaling molecules in the body, playing crucial roles in processes like healing, immune regulation, and hormone production. This episode dives deep into the various applications of peptides, including their potential for anti-aging, weight loss, injury recovery, and cognitive enhancement. The discussion also emphasizes the importance of using peptides under professional care to avoid risks associated with self-diagnosis and treatment. With insights backed by personal experiences and research, listeners will gain a comprehensive understanding of how peptides can be integrated into a health regimen for improved vitality and well-being.

Welcome back! Today, we're diving into an exciting new compound called SLU PP332, or "Slupp," which has the potential to mimic the benefits of exercise at a cellular level, even when you're not physically active. Tara shares her personal journey with Slupp emphasizing its role as a possible enhancement to exercise rather than a replacement. She discusses the groundbreaking research on Sloop, highlighting its effects on energy production, fat metabolism, and overall metabolic health. With insights from her own experience and feedback from friends and clients, she provides a comprehensive overview of how this compound could be a game-changer in optimizing health and fitness. Tune in to learn more about Slupp and its implications for those looking to maximize their wellness journey.

Takeaways:

• The synthetic compound Slupp mimics exercise benefits at the cellular level without actual physical activity.
• Slupp acts as an agonist for estrogen-related receptors, enhancing energy production and fat metabolism.
• Research on Slupp shows significant fat loss and improved metabolic health in mice, although human studies are pending.
• Using Slupp can enhance workout results and serve as a safety net when unable to exercise.
• While Slupp is promising, it is essential to consult with healthcare practitioners before use.
• The compound shows potential in improving endurance and cognitive clarity during physical activities.

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

SLU-PP-332 Research Links:

Exercise-Mimicking Drug Sheds Weight, Boosts Muscle Activity in Mice: This article from the University of Florida News discusses how SLU-PP-332 led to significant weight loss and enhanced endurance in obese mice.

University of Florida News

A Synthetic ERR Agonist Alleviates Metabolic Syndrome: Published in the Journal of Pharmacology and Experimental Therapeutics, this study explores how SLU-PP-332 improves metabolic parameters in mouse models of obesity and metabolic syndrome.

Newswise

A Synthetic ERRα Agonist Induces an Acute Aerobic Exercise Response and Enhances Exercise Capacity: This preprint study details how SLU-PP-332 activates an aerobic exercise genetic program in skeletal muscle, enhancing exercise endurance in mice.

BioRxiv

Setting realistic New Year's resolutions is crucial for achieving long-term success, as studies show that only 8% of people actually meet their goals. This episode dives into the common pitfalls that lead to failure, such as setting unrealistic expectations, adopting an all-or-nothing mindset, and neglecting emotional support. Tara emphasizes the importance of flexibility in goal-setting, advocating for incremental changes and self-compassion rather than perfectionism. The discussion also highlights the significance of understanding one's "why" and aligning goals with personal identity to foster lasting motivation. With practical tips and personal anecdotes, this episode offers valuable insights to help listeners navigate their health journeys in a more sustainable way.

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

Welcome back, everyone! This episode delves into the key takeaways from 2024, emphasizing that it’s never too late to start making positive changes in your life. Tara shares personal experiences and insights gained over the past year, highlighting the importance of understanding that wellness is not a one-size-fits-all journey. From overcoming the fear of failure to recognizing the power of small, incremental changes, listeners are encouraged to embrace their unique paths to health and happiness. The discussion also touches upon the significance of attitude and intentionality as crucial factors in achieving long-term success. Join Tara and explore these lessons that will help inspire you to take steps toward your own wellness journey in the coming year!

Takeaways:

• It's never too late to start making positive changes in your life.
• Wellness is a unique journey for each individual, not a one-size-fits-all approach.
• Small, incremental changes over time lead to sustainable health and lifestyle improvements.
• Ditch the mindset that effective routines must be grueling and unpleasant to yield results.
• Your mindset and attitude are crucial for success in health and fitness journeys.
• Embrace the idea that personal experiences shape unique paths to wellness and nutrition.

Podcast episode links

Apsen Household products: https://shareasale.com/r.cfm?b=1736653&u=4252226&m=108208&urllink=&afftrack=

EWG (Environmental Working Group):https://www.ewg.org/

West Wellness and Longevity Links

• Are you ready to make change but don't know where to start. Book a free 30 min consultation here.https://www.westwellnessatx.com/get-started
• Have questions? Feel free to reach out to me at: tarawest@westwellnessatx.com
• Follow me on instagram @westwellnessatx

This podcast episode focuses on the importance of reducing household toxins, highlighting the challenges many face when trying to create a healthier living environment. The host shares personal experiences and insights on various common toxic substances found in everyday products, including cleaning supplies, cookware, and personal care items. Emphasizing the cumulative health risks associated with exposure to these toxins, the discussion covers harmful chemicals like phthalates, VOCs, and BPA, detailing their negative effects on hormonal balance, reproductive health, and overall wellness. Listeners are encouraged to take gradual steps towards detoxifying their homes, such as opting for phthalate-free cleaning products and avoiding non-stick cookware containing PFAS. The episode provides practical tips and resources to help individuals make informed choices, ultimately aiming to inspire a healthier lifestyle for themselves and their families.

Takeaways:

• Cleaning products often contain toxic chemicals like ammonia, bleach, and phthalates, which disrupt hormones.
• VOCs, or volatile organic compounds, can lead to respiratory issues and chronic diseases over time.
• Non-stick cookware often contains harmful PFAS chemicals that can lead to serious health risks.
• Personal care products frequently have parabens and sulfates that can disrupt hormonal balance and skin health.
• BPA is a pervasive chemical in plastics that mimics estrogen, affecting reproductive health and metabolism.
• Taking small steps to limit exposure to household toxins can significantly improve overall health over time.