The Great American Drug Deal
A New Prescription for Innovative and Affordable Medicines
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The Great American Drug Deal
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Narrated by:
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Sean Pratt
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By:
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Peter Kolchinsky
About this listen
Developing life-changing drugs is risky and expensive, but that’s not what makes them unaffordable.
Drug pricing is a staple of every news cycle and political debate. And while we’ve struggled for decades to agree on solutions that serve all patients without jeopardizing the invention of new medicines, many Americans suffer because they can’t afford the drugs they need. Do we really have to choose between affordability and innovation?
In The Great American Drug Deal, scientist and industry expert Peter Kolchinsky answers this question with a decisive "no". The pharmaceutical industry’s commitment to creating new lifesaving drugs destined to become inexpensive generics can be balanced by the healthcare system’s commitment to making those drugs affordable for all patients - a biotech social contract.
Through deep research and compelling stories of breakthroughs and breakdowns, Kolchinsky presents solutions for striking a balance that are bold yet realistic and tackle today’s most pressing questions, including:
- Why doesn’t insurance make drugs affordable?
- How can we prevent price-jacking of older drugs?
- Why are drugs more expensive in America than elsewhere?
- How can we guarantee that all medicines eventually go generic so they are only temporarily expensive?
- What systemic failures led to the opioid crisis, and how can we prevent the next one?
The Great American Drug Deal offers clear-eyed scrutiny of all players in the industry and examines vital ideas for closing loopholes, encouraging investment, dealing with bad actors, and educating consumers. It’s time we resolve to support patients and fuel discoveries that ease suffering now and for generations to come.
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-
Story4.5 out of 5 stars 115
A bold new remedy for the sprawling and wasteful health care industry. In this provocative book, Jonathan Bush, cofounder and CEO of athenahealth, calls for a revolution in health care to give customers more choices, freedom, power, and information, and at far lower prices.
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2 out of 5 stars
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No critical thinking
- By Steve from MD on 07-31-14
By: Jonathan Bush, and others
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The Price We Pay
- What Broke American Health Care - and How to Fix It
- By: Marty Makary MD
- Narrated by: Marty Makary MD
- Length: 9 hrs and 29 mins
- Unabridged
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Overall5 out of 5 stars 937
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Performance5 out of 5 stars 816
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Story5 out of 5 stars 810
One in five Americans now has medical debt in collections and rising health care costs today threaten every small business in America. Dr Makary, one of the nation's leading health care experts, travels across America and details why health care has become a bubble. Drawing from on-the-ground stories, his research and his own experience, The Price We Pay paints a vivid picture of price-gouging, middlemen and a series of elusive money games in need of a serious shake-up.
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5 out of 5 stars
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Very important book!
- By Wayne on 05-17-21
By: Marty Makary MD
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Phishing for Phools
- The Economics of Manipulation and Deception
- By: George A. Akerlof, Robert J. Shiller
- Narrated by: Bronson Pinchot
- Length: 7 hrs and 11 mins
- Unabridged
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Overall4 out of 5 stars 349
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Performance4 out of 5 stars 300
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Story4 out of 5 stars 299
Ever since Adam Smith, the central teaching of economics has been that free markets provide us with material well-being, as if by an invisible hand. In Phishing for Phools, Nobel Prize-winning economists George Akerlof and Robert Shiller deliver a fundamental challenge to this insight, arguing that markets harm as well as help us. As long as there is profit to be made, sellers will systematically exploit our psychological weaknesses and our ignorance through manipulation and deception.
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4 out of 5 stars
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Useful for a certain audience, but ...
- By Philo on 02-29-16
By: George A. Akerlof, and others
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The Social Transformation of American Medicine
- The Rise of a Sovereign Profession and the Making of a Vast Industry
- By: Paul Starr
- Narrated by: Sean Runnette
- Length: 24 hrs and 5 mins
- Unabridged
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Overall4.5 out of 5 stars 114
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Performance4.5 out of 5 stars 93
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Story4.5 out of 5 stars 94
Considered the definitive history of the American healthcare system, The Social Transformation of American Medicine examines how the roles of doctors, hospitals, health plans, and government programs have evolved over the last two and a half centuries. Updated with a new preface and an epilogue analyzing developments since the early 1980s, this new edition is a must-listen for anyone concerned about the future of our fraught healthcare system.
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5 out of 5 stars
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Fascinating Survey of Healthcare in Amerixa
- By Rob on 06-24-19
By: Paul Starr
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The Great Escape
- Health, Wealth, and the Origins of Inequality
- By: Angus Deaton
- Narrated by: Matthew Brenher
- Length: 12 hrs and 13 mins
- Unabridged
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Overall4.5 out of 5 stars 251
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Performance4.5 out of 5 stars 206
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Story4.5 out of 5 stars 206
The world is a better place than it used to be. People are healthier, wealthier, and live longer. Yet the escapes from destitution by so many has left gaping inequalities between people and nations. In The Great Escape, Angus Deaton - one of the foremost experts on economic development and on poverty - tells the remarkable story of how, beginning 250 years ago, some parts of the world experienced sustained progress, opening up gaps and setting the stage for today's disproportionately unequal world.
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1 out of 5 stars
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not worth listening
- By Kyung on 04-26-20
By: Angus Deaton
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The Great Reversal
- How America Gave Up on Free Markets
- By: Thomas Philippon
- Narrated by: Walter Dixon
- Length: 10 hrs and 1 min
- Unabridged
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Overall4.5 out of 5 stars 139
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Performance4.5 out of 5 stars 107
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Story4.5 out of 5 stars 107
Why are cellphone plans so much more expensive in the United States than in Europe? It seems a simple question. But the search for an answer took Thomas Philippon on an unexpected journey through some of the most complex and hotly debated issues in modern economics. Ultimately, he reached a surprising conclusion: American markets, once a model for the world, are giving up on healthy competition.
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4 out of 5 stars
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Eye-opening, but better as a book - a must-READ
- By Ash on 11-29-19
By: Thomas Philippon
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Deaths of Despair and the Future of Capitalism
- By: Anne Case, Angus Deaton
- Narrated by: Kate Harper
- Length: 11 hrs and 38 mins
- Unabridged
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Overall4.5 out of 5 stars 185
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Performance4.5 out of 5 stars 148
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Story4.5 out of 5 stars 148
Life expectancy in the United States has recently fallen for three years in a row - a reversal not seen since 1918 or in any other wealthy nation in modern times. In the past two decades, deaths of despair from suicide, drug overdose, and alcoholism have risen dramatically, and now claim hundreds of thousands of American lives each year - and they're still rising. Case and Deaton, known for first sounding the alarm about deaths of despair, explain the overwhelming surge in these deaths and shed light on the social and economic forces that are making life harder for the working class.
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2 out of 5 stars
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So many words, so little insight
- By Trebla on 03-22-20
By: Anne Case, and others
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The Prosperity Paradox
- How Innovation Can Lift Nations out of Poverty
- By: Clayton M. Christensen, Efosa Ojomo, Karen Dillon
- Narrated by: Mike Chamberlain
- Length: 9 hrs and 37 mins
- Unabridged
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Overall4.5 out of 5 stars 382
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Performance4.5 out of 5 stars 308
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Story4.5 out of 5 stars 304
Clayton M. Christensen, the author of such business classics as The Innovator’s Dilemma and the New York Times best-seller How Will You Measure Your Life, and coauthors Efosa Ojomo and Karen Dillon reveal why so many investments in economic development fail to generate sustainable prosperity and offers a groundbreaking solution for true and lasting change.
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2 out of 5 stars
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Simplistic, lack of insights
- By D. Cameron on 05-24-21
By: Clayton M. Christensen, and others
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The HPV Vaccine on Trial
- Seeking Justice for a Generation Betrayed
- By: Mary Holland, Kim Mack Rosenberg, Eileen Iorio
- Narrated by: Caroline Slaughter
- Length: 13 hrs and 41 mins
- Unabridged
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Overall5 out of 5 stars 58
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Performance5 out of 5 stars 50
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Story5 out of 5 stars 51
Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer - as we are assured the human papillomavirus (HPV) vaccine will - seemed like a game-changer. Since 2006, over 80 countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide. The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle.
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5 out of 5 stars
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Outstanding Investigative Book!
- By Barbara Loeppke on 10-02-19
By: Mary Holland, and others
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Super Crunchers
- Why Thinking-by-Numbers Is the New Way to Be Smart
- By: Ian Ayres
- Narrated by: Michael Kramer
- Length: 7 hrs and 34 mins
- Unabridged
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Overall4 out of 5 stars 849
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Performance4.5 out of 5 stars 273
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Story4 out of 5 stars 275
Today, number crunching affects your life in ways you might never imagine. In this lively and groundbreaking new audiobook, economist Ian Ayres shows how today's best and brightest organizations are analyzing massive databases at lightening speed to provide greater insights into human behavior. They are the Super Crunchers.
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5 out of 5 stars
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Great book on
- By Jon on 01-31-08
By: Ian Ayres
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Economics for the Common Good
- By: Jean Tirole, Steven Rendell - translator
- Narrated by: Jonathan Davis
- Length: 18 hrs and 54 mins
- Unabridged
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Overall4.5 out of 5 stars 56
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Performance4.5 out of 5 stars 44
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Story4.5 out of 5 stars 42
When Jean Tirole won the 2014 Nobel Prize in Economics, he suddenly found himself being stopped in the street by complete strangers and asked to comment on issues of the day, no matter how distant from his own areas of research. His transformation from academic economist to public intellectual prompted him to reflect further on the role economists and their discipline play in society. The result is Economics for the Common Good, a passionate manifesto for a world in which economics, far from being a "dismal science," is a positive force for the common good.
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4 out of 5 stars
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A Great Overview of the Challenges of Modern Econ
- By Zach Sullivan on 08-06-18
By: Jean Tirole, and others
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Power and Prediction
- The Disruptive Economics of Artificial Intelligence
- By: Ajay Agrawal, Joshua Gans, Avi Goldfarb
- Narrated by: Tom Beyer
- Length: 10 hrs and 7 mins
- Unabridged
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Overall4.5 out of 5 stars 100
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Performance4.5 out of 5 stars 88
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Story4 out of 5 stars 88
In their bestselling first book, Prediction Machines, eminent economists Ajay Agrawal, Joshua Gans, and Avi Goldfarb explained the simple yet game-changing economics of AI. Now, in Power and Prediction, they go deeper, examining the most basic unit of analysis: the decision. The authors explain that the two key decision-making ingredients are prediction and judgment, and we perform both together in our minds, often without realizing it.
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5 out of 5 stars
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Inspire system thinking with informative examples
- By Lucy A. Pithecus on 11-16-22
By: Ajay Agrawal, and others
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The White Man's Burden
- Why the West's Efforts to Aid the Rest Have Done So Much Ill and So Little Good
- By: William Easterly
- Narrated by: Mike Chamberlain
- Length: 14 hrs and 35 mins
- Unabridged
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Overall4.5 out of 5 stars 78
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Performance4.5 out of 5 stars 68
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Story4.5 out of 5 stars 68
In his previous book, The Elusive Quest for Growth, William Easterly criticized the utter ineffectiveness of Western organizations to mitigate global poverty, and he was promptly fired by his then-employer, the World Bank. The White Man's Burden is his widely anticipated counterpunch - a brilliant and blistering indictment of the West's economic policies for the world's poor.
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4 out of 5 stars
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A Bit Repetitive
- By Amazon Customer on 04-27-19
By: William Easterly
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Saving Normal
- An Insider’s Revolt Against out-of-Control Psychiatric Diagnosis, DSM-5, Big Pharma, and the Medicalization of Ordinary Life
- By: Allen Frances MD
- Narrated by: Paul Boehmer
- Length: 11 hrs and 53 mins
- Unabridged
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Overall4.5 out of 5 stars 134
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Performance4.5 out of 5 stars 111
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Story4.5 out of 5 stars 111
In Saving Normal, Allen Frances, one of the world's most influential psychiatrists, warns that mislabeling everyday problems as mental illness has shocking implications for individuals and society: Stigmatizing a healthy person as mentally ill leads to unnecessary, harmful medications, the narrowing of horizons, misallocation of medical resources, and draining of the budgets of families and the nation.
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5 out of 5 stars
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Right on the money
- By Mentecuerpo on 03-29-19
By: Allen Frances MD
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The Undercover Economist
- By: Tim Harford
- Narrated by: Robert Ian Mackenzie
- Length: 10 hrs and 6 mins
- Unabridged
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Overall4 out of 5 stars 542
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Performance4 out of 5 stars 326
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Story4 out of 5 stars 324
Author of the extremely popular "Dear Economist" column in Financial Times, Tim Harford reveals the economics behind everyday phenomena in this highly entertaining and informative book. Can a book about economics be fun to read? It can when Harford takes the reins, using his trademark wit to explain why it costs an arm and a leg to buy a cappuccino and why it's nearly impossible to purchase a decent used car.
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4 out of 5 stars
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Everyone needs to know this.
- By Paul Norwood on 04-24-06
By: Tim Harford
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Unaccountable
- What Hospitals Won't Tell You and How Transparency Can Revolutionize Health Care
- By: Marty Makary
- Narrated by: Robertson Dean
- Length: 7 hrs and 16 mins
- Unabridged
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Overall4.5 out of 5 stars 253
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Performance4.5 out of 5 stars 222
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Story4.5 out of 5 stars 224
Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's best-selling The Checklist Manifesto. As a busy surgeon who has worked in many of the best hospitals in the nation, he can testify to the amazing power of modern medicine to cure. But he's also been a witness to a medical culture that routinely leaves surgical sponges inside patients, amputates the wrong limbs, and overdoses children because of sloppy handwriting. Over the last 10 years, neither error rates nor costs have come down, despite scientific progress.
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5 out of 5 stars
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Everyone should read this book.
- By Julie on 06-11-16
By: Marty Makary