The Breakthrough
Immunotherapy and the Race to Cure Cancer
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The Breakthrough
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Narrated by:
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Will Collyer
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Charles Graeber
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By:
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Charles Graeber
About this listen
New York Times best-selling author Charles Graeber tells the astonishing story of the group of scientists working on a code that can enable the human immune system to fight - and perhaps even cure - cancer.
For decades, scientists have puzzled over one of medicine’s greatest mysteries: why doesn’t our immune system fight cancer the way it does other diseases? The answer is a series of tricks that cancer has developed to turn off normal immune responses - tricks that scientists have only recently discovered and now are learning to defeat. We are in the midst of a revolution in our understanding of cancer and how to beat it.
Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing and Nobel Prize-winning scientific discoveries that unleash our natural ability to recognise and defeat cancer, as told through the experiences of the patients, physicians, and immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, and the definitive account of a historic moment in medical science.
©2018 Charles Graeber (P)2019 Hachette AudioListeners also enjoyed...
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- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Overall4.5 out of 5 stars 4,890
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Performance4.5 out of 5 stars 4,233
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Story4.5 out of 5 stars 4,215
Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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4 out of 5 stars
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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The Demon Under The Microscope
- By: Thomas Hager
- Narrated by: Stephen Hoye
- Length: 12 hrs and 14 mins
- Unabridged
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Overall4.5 out of 5 stars 3,488
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Performance4.5 out of 5 stars 2,543
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Story4.5 out of 5 stars 2,541
The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.
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5 out of 5 stars
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Great Book!!!!!
- By Amazon Customer on 05-21-08
By: Thomas Hager
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Overall4.5 out of 5 stars 52
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Performance4.5 out of 5 stars 42
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Story4.5 out of 5 stars 42
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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5 out of 5 stars
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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Rigor Mortis
- How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions
- By: Richard Harris
- Narrated by: Joe Delafield
- Length: 5 hrs and 56 mins
- Unabridged
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Overall4.5 out of 5 stars 117
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Performance4.5 out of 5 stars 100
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Story4.5 out of 5 stars 99
American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system - before it's too late.
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5 out of 5 stars
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Eye opening introduction to biomedical R&D
- By Amazon Customer on 09-18-18
By: Richard Harris
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Influenza
- The Hundred-Year Hunt to Cure the 1918 Spanish Flu Pandemic
- By: Dr. Jeremy Brown
- Narrated by: Holter Graham
- Length: 6 hrs and 28 mins
- Unabridged
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Overall4.5 out of 5 stars 361
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Performance4.5 out of 5 stars 309
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Story4.5 out of 5 stars 307
On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?
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5 out of 5 stars
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Important read
- By Kathryn C. on 12-21-18
By: Dr. Jeremy Brown
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Tomorrowland
- Our Journey From Science Fiction to Science Fact
- By: Steven Kotler
- Narrated by: Tom Parks
- Length: 8 hrs and 58 mins
- Unabridged
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Overall4 out of 5 stars 429
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Performance4.5 out of 5 stars 363
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Story4 out of 5 stars 363
New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.
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3 out of 5 stars
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Covers a lot of different topics in many industries
- By ErnieA on 06-27-15
By: Steven Kotler
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
- Unabridged
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Overall5 out of 5 stars 808
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Performance4.5 out of 5 stars 721
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Story5 out of 5 stars 719
Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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5 out of 5 stars
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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Happy Accidents
- Serendipity in Major Medical Breakthroughs in the Twentieth Century
- By: Morton A. Meyers
- Narrated by: Richard Waterhouse
- Length: 12 hrs and 37 mins
- Unabridged
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Overall4.5 out of 5 stars 50
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Performance4 out of 5 stars 45
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Story4.5 out of 5 stars 44
Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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1 out of 5 stars
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Don't waste your money!
- By Amazon Customer on 03-20-16
By: Morton A. Meyers
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The Heart Healers
- The Misfits, Mavericks, and Rebels Who Created the Greatest Medical Breakthrough of Our Lives
- By: James Forrester MD
- Narrated by: Jonathan Yen
- Length: 15 hrs and 45 mins
- Unabridged
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Overall4.5 out of 5 stars 91
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Performance4.5 out of 5 stars 82
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Story4.5 out of 5 stars 82
At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.
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5 out of 5 stars
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Great review of the landmark achievements in Cardiology.
- By Trauma NP on 12-14-15
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The Family That Couldn't Sleep
- A Medical Mystery
- By: D.T. Max
- Narrated by: Grover Gardner
- Length: 8 hrs and 45 mins
- Unabridged
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Overall4 out of 5 stars 488
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Performance4.5 out of 5 stars 270
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Story4.5 out of 5 stars 273
For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.
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5 out of 5 stars
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A great scientific mystery
- By David on 11-04-06
By: D.T. Max
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Less Medicine, More Health
- 7 Assumptions That Drive Too Much Medical Care
- By: H. Gilbert Welch
- Narrated by: L. J. Ganser
- Length: 8 hrs and 18 mins
- Unabridged
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Overall5 out of 5 stars 102
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Performance5 out of 5 stars 91
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Story4.5 out of 5 stars 91
The author of the highly acclaimed Overdiagnosed describes seven widespread assumptions that encourage excessive, often ineffective, and sometimes harmful medical care. You might think the biggest problem in medical care is that it costs too much. Or that health insurance is too expensive, too uneven, too complicated - and gives you too many forms to fill out. But the central problem is that too much medical care has too little value.
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4 out of 5 stars
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The truth will set you free
- By Rene B Milner on 04-01-16
By: H. Gilbert Welch
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The Secret History of the War on Cancer
- By: Devra Davis Ph.D.
- Narrated by: Pam Ward
- Length: 19 hrs and 11 mins
- Unabridged
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Overall4.5 out of 5 stars 36
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Performance4.5 out of 5 stars 23
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Story4.5 out of 5 stars 24
The War on Cancer was run by leaders of industries that made cancer-causing products and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies, a legacy that persists to this day.
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2 out of 5 stars
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Silly Book
- By Adam Smith on 12-24-14
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Flu
- The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus that Caused It
- By: Gina Kolata
- Narrated by: Gina Kolata
- Length: 6 hrs and 14 mins
- Abridged
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Overall4 out of 5 stars 488
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Performance3.5 out of 5 stars 230
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Story4.5 out of 5 stars 227
Feeling feverish, tired, or achy? Listening to Gina Kolata's engrossing account of the 1918 Influenza epidemic is sure to give you the chills. A gripping work of science writing, Flu addresses the prospects for a great epidemic recurring, and considers what can be done to prevent it.
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1 out of 5 stars
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overexcited
- By Marilyn on 07-23-03
By: Gina Kolata
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How Doctors Think
- By: Jerome Groopman M.D.
- Narrated by: Michael Prichard
- Length: 10 hrs and 27 mins
- Unabridged
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Overall4 out of 5 stars 749
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Performance4 out of 5 stars 393
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Story4.5 out of 5 stars 394
On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.
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3 out of 5 stars
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Disappointing
- By Audiophile on 05-13-07
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Polio
- An American Story
- By: David M. Oshinsky
- Narrated by: Jonathan Hogan
- Length: 14 hrs and 37 mins
- Unabridged
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Overall4.5 out of 5 stars 594
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Performance4.5 out of 5 stars 424
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Story4.5 out of 5 stars 423
This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.
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5 out of 5 stars
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Wonderful
- By Patricia B Tripoli on 07-22-08