Cracking the Aging Code
The New Science of Growing Old - and What It Means for Staying Young
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Narrated by:
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Stephen McLaughlin
About this listen
A revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it.
In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that "just happens", nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever threatened by cyclic swings that can lead to extinction. When a population grows too fast, it can put itself at risk of a wholesale wipeout.
Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection. This dynamic new understanding of aging is provocative, entertaining, and pioneering and will challenge the way we understand aging, death, and just what makes us human.
©2016 Josh Mitteldorf and Dorion Sagan (P)2016 Macmillan AudioListeners also enjoyed...
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Great Scientific Writing/ Wrong Narrator
- By Richard on 11-24-15
By: John Parrington
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- By: George Johnson
- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
- Unabridged
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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How to Build a Dinosaur
- Extinction Doesn't Have to Be Forever
- By: Jack Horner, James Gorman
- Narrated by: Patrick Lawlor
- Length: 6 hrs and 36 mins
- Unabridged
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In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.
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Good book but misplaced title
- By Robert on 06-19-15
By: Jack Horner, and others
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- By: Rob DeSalle, Susan L. Perkins
- Narrated by: Stephen McLaughlin
- Length: 7 hrs and 25 mins
- Unabridged
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Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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I learned so much from this book. I am happy.
- By Jonathan Miller on 09-08-18
By: Rob DeSalle, and others
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At the Edge of Uncertainty
- 11 Discoveries Taking Science by Surprise
- By: Michael Brooks
- Narrated by: Sean Runnette
- Length: 9 hrs and 12 mins
- Unabridged
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The atom, the big bang, DNA, natural selection - all are ideas that have revolutionized science; and all were dismissed out of hand when they first appeared. The surprises haven't stopped in recent years, and in At the Edge of Uncertainty, best-selling author Michael Brooks investigates the new wave of radical insights that are shaping the future of scientific discovery.
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All smoke, no fire
- By Kenton on 07-25-15
By: Michael Brooks
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The Story of the Human Body
- Evolution, Health, and Disease
- By: Daniel Lieberman
- Narrated by: Sean Runnette
- Length: 14 hrs and 54 mins
- Unabridged
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In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.
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Could Have Been Good, but...
- By Trebla on 04-08-18
By: Daniel Lieberman
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
- Unabridged
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
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Arrival of the Fittest
- Solving Evolution's Greatest Puzzle
- By: Andreas Wagner
- Narrated by: Sean Pratt
- Length: 8 hrs and 29 mins
- Unabridged
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In Arrival of the Fittest, renowned evolutionary biologist Andreas Wagner draws on over 15 years of research to present the missing piece in Darwin's theory. Using experimental and computational technologies that were heretofore unimagined, he has found that adaptations are not just driven by chance, but by a set of laws that allow nature to discover new molecules and mechanisms in a fraction of the time that random variation would take.
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Robustness makes for an interesting life and book
- By Gary on 11-29-14
By: Andreas Wagner
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Missing Microbes
- How the Overuse of Antibiotics Is Fueling Our Modern Plagues
- By: Martin J. Blaser
- Narrated by: Patrick Lawlor
- Length: 8 hrs and 43 mins
- Unabridged
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In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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Very enlightening and information well supported
- By James on 05-03-15
By: Martin J. Blaser
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
What listeners say about Cracking the Aging Code
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- mojo4life
- 02-06-21
A credible hypothesis of aging
First off, the narrator was great. As a co-author he never mispronounced a scientific word which was refreshing. My biggest concern reading (listening to) this book was that it was outdated now (in 2021) because the science is moving so fast. Welp, I was SO wrong. This read like a breakthrough text to me. To other commenters decrying political views in the book, I can only say that it was contained to a paragraph or two, and used as an analogy. It's honestly quite strange that anyone would mention that in the review, as it was 0.001% of the text.
Before this book I read Sinclair's Lifespan. While Sinclair's book presents some very profound experiments, this text is on a different level. It pulls together evolutionary biology and modern bioscience. There is a very large chunk of the book where the author is arguing group selection theory that can be skipped over if you are not a hardcore neo-darwinist type (i.e. prestigious old school evolutionary biologist.) The last 1/3 of the book is gold when it comes to helping you understand aging and what you can do about it. My favorite take away tip is the concept of mutually redundant benefit, where you end up adding the same 3 years to your life over and over again (this is bad, or a waste of money at best.) He outlines the different pathways which work separately which you can activate. However, the author also heavily focuses on what is missing in current science and where we need to go. Some of this has been addressed over the last 10 years but sadly some science is lagging. According to the author, "winding back the aging clock 4 years would save more lives than a perfect cure for cancer."
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- Daniel L Stickler II
- 12-06-16
Outstanding
This is an eye opening paradigm shift in how we view aging. Well referenced and thought provoking
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1 person found this helpful
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Overall
- David R. Kent
- 10-11-17
A mix of good and bad
The first few and last few chapters of this book are terrible. The author goes on and on with his amateurish thoughts on philosophy, economics, and other subjects. The middle chapters were a very interesting coverage of the evolution of aging as well as research on aging. The book is worth it for the middle chapters. The begining almost made me quit the book early, and the end made me question the credibility of the middle chapters.
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4 people found this helpful
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- Meryl
- 12-20-21
Fascinating!
I bought this book when I read a review that mentioned David Sinclair’s Lifespan, which is one of my top 2 favorite books. Cracking the Aging Code is full of fascinating hypotheses, theories, science and evolutionary biology. Did not want to miss a single sentence and in fact rewound many times to make sure I hadn’t missed a thing. Could have listened to 10 more hours of it.
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- John D. Furber
- 06-18-21
Good attempt to cover a big subject
This is an impressively comprehensive coverage of the science, history, and philosophy of why we age, and the efforts of scientists to understand and develop effective therapies. Written in 2015, some of the statements are becoming outdated. But much is valuable and relevant. This book would be especially interesting to those who are already students or researchers in the field, because they can appreciate how it fits in with other viewpoints on how aging occurs. Unfortunately, the audiobook reader mispronounces many technical terms and the names of many key scientists and historical figures.
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- Frank
- 08-21-16
Liberal agenda
What would have made Cracking the Aging Code better?
Stick with science and not go off on tangents on how socialism is better than capitalism.
What was most disappointing about Josh Mitteldorf and Dorion Sagan ’s story?
Too biased.
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9 people found this helpful
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- sammy81
- 08-01-22
No new information just arguing
Awful just awful, and not what advertised to be. It’s just one man’s opining why he’s right about evolution and everyone else is wrong. Not science, just opinions, and no anti-aging insights as advertised. If I have to hear the word “neo-Darwinian one more time I’ll lose my mind. Awful book
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- Doug Fischer
- 03-05-17
Not what I expected.
This entire book is simply trying to prove (to the public, or the science community, I couldn't tell where it was aimed) that group selection is the main culprit behind why we are programmed to age. They do this by attacking the viewpoint of every single other theory accepted by science up to this point. Is somebody detesting the 'Disposable Soma Theory' from 92 different approaches something that may hold you interest? Would you mind hearing the term 'Neo-Darwinian theory' 492 times? If so this book is for you. But that's not what I was looking for. And the cherry on top was the fact that the narrator to the audio book sounds like Spicoli from Fast Times at Ridgemont High. A southern California surfer may not have been the best choice to narrate this book.
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7 people found this helpful