
Lifespan
Why We Age - and Why We Don't Have To
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Narrado por:
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David A. Sinclair PhD
Acerca de esta escucha
Audio bonus! Includes exclusive conversations with the authors!
From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.
For decades, experts have believed that we are at the mercy of our genes and that natural damage to our genes - the kind that inevitably happens as we get older - makes us become sick and grow old.
But what if everything you think you know about aging is wrong? What if aging is a disease - and that disease is treatable?
In Lifespan, one of the world’s foremost experts on aging and genetics reveals a groundbreaking new theory that will forever change the way we think about why we age and what we can do about it. Aging isn’t immutable; we can have far more control over it than we realize. This eye-opening and provocative work takes us to the front lines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs - many from Dr. David Sinclair’s own lab - that demonstrate how we can slow down, or even reverse, the genetic clock. The key is activating newly discovered vitality genes - the decedents of an ancient survival circuit that is both the cause of aging and the key to reversing it. Dr. Sinclair shares the emerging technologies and simple lifestyle changes - such as intermittent fasting, cold exposure, and exercising with the right intensity - that have been shown to help lead to longer lives.
Lifespan provides a road map for taking charge of our own health destiny and a bold new vision for the future when humankind is able to live to be 100 years young.
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2019 David Sinclair (P)2019 Simon & Schuster AudioLos oyentes también disfrutaron...
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Very enlightening and information well supported
- De James en 05-03-15
De: Martin J. Blaser
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- De: George Johnson
- Narrado por: Arthur Morey
- Duración: 8 h y 19 m
- Versión completa
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Historia
When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- De Digital Dilema en 09-06-13
De: George Johnson
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Ravenous
- Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection
- De: Sam Apple
- Narrado por: Mark Bramhall
- Duración: 12 h y 58 m
- Versión completa
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The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.
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Highly recommended, a must read.
- De Joerg en 06-10-21
De: Sam Apple
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Denialism
- How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives
- De: Michael Specter
- Narrado por: Richard Poe
- Duración: 8 h y 33 m
- Versión completa
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Historia
New Yorker staff writer Michael Specter has twice won the Global Health Council’s Excellence in Media Award, as well as the Science Journalism Award from the American Association for the Advancement of Science. In Denialism, he fervently argues that people are turning away from new technologies and engaging in a kind of magical thinking that is hindering scientific progress.
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A compelling read
- De S en 05-17-11
De: Michael Specter
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- De: Francis S. Collins
- Narrado por: Greg Itzin
- Duración: 10 h y 45 m
- Versión completa
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Historia
A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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The future of medicine
- De Ronald E en 04-12-10
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- De: Moises Velasquez-Manoff
- Narrado por: Chris Sorensen
- Duración: 17 h y 6 m
- Versión completa
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Historia
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- De rtgymnast en 11-03-17
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Pandora's Seed
- The Unforeseen Cost of Civilization
- De: Spencer Wells
- Narrado por: Spencer Wells
- Duración: 6 h y 40 m
- Versión completa
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Historia
This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.
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Short and unfocused, but often quite interesting.
- De Alan en 06-23-10
De: Spencer Wells
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Plague of Corruption
- Restoring Faith in the Promise of Science
- De: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrado por: Mariel Hemingway
- Duración: 10 h y 10 m
- Versión completa
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Historia
Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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If only most of the public knew these facts
- De David Getoff, CCN en 06-18-20
De: Dr. Judy Mikovits, y otros
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- De: Thomas Hager
- Narrado por: Angelo Di Loreto
- Duración: 8 h y 39 m
- Versión completa
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Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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Engrossing to physicians & lay persons alike
- De C. White en 03-08-19
De: Thomas Hager
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The Truth About Cancer
- De: Ty M. Bollinger
- Narrado por: Ty M. Bollinger
- Duración: 9 h y 11 m
- Versión completa
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General
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Narración:
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Historia
One out of three women alive today, and one out of two men, will face a cancer diagnosis, according to the World Health Organization. Ty Bollinger takes this personally: in the course of a decade, he says, "I lost my entire family to cancer. I don't believe I had to lose them." The Truth about Cancer has been written for one simple reason: to share the knowledge we need to protect ourselves, treat ourselves, and in some cases save our lives or the lives of those we love.
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save a life with this valuable information.
- De edwin matias en 12-30-16
De: Ty M. Bollinger
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The Story of the Human Body
- Evolution, Health, and Disease
- De: Daniel E. Lieberman
- Narrado por: Sean Runnette
- Duración: 14 h y 54 m
- Versión completa
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General
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Narración:
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Historia
In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.
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Could Have Been Good, but...
- De Trebla en 04-08-18
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p53: The Gene That Cracked the Cancer Code
- De: Sue Armstrong
- Narrado por: Elizabeth Jasicki
- Duración: 9 h y 55 m
- Versión completa
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General
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Narración:
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Historia
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- De Adriana en 12-25-14
De: Sue Armstrong
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- De: Daniel M. Davis
- Narrado por: Christopher Grove
- Duración: 7 h y 48 m
- Versión completa
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General
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Narración:
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Historia
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- De Howard Sterling en 06-29-16
De: Daniel M. Davis
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- De: Leonardo Trasande MD MPP
- Narrado por: Leonardo Trasande MD MPP
- Duración: 6 h y 44 m
- Versión completa
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General
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Narración:
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Historia
Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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The Must Read Book of 2019 is here early on Audio!
- De Ryan S en 12-21-18
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Editing Humanity
- The CRISPR Revolution and the New Era of Genome Editing
- De: Kevin Davies
- Narrado por: Kevin Davies
- Duración: 16 h y 17 m
- Versión completa
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General
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Narración:
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Historia
Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.
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Excellent content, solid execution
- De Samuel Finlayson en 01-25-21
De: Kevin Davies
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Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body - how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted."
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Must Read for the Sheer Fun of It
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The Molecule of More
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In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and more.
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Did you know conservatives have more orgasms?
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An Internet in Your Head
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Whether we realize it or not, we think of our brains as computers. In neuroscience, the metaphor of the brain as a computer has defined the field for much of the modern era. But as neuroscientists increasingly reevaluate their assumptions about how brains work, we need a new metaphor to help us ask better questions. The computational neuroscientist Daniel Graham offers an innovative paradigm for understanding the brain. He argues that the brain is not like a single computer—it is a communication system, like the internet.
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The Science and Technology of Growing Young
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The prospect of living to 200 years old isn’t science fiction anymore. A leader in the emerging field of longevity offers his perspective on what cutting-edge breakthroughs are on the horizon, as well as the practical steps we can take now to live healthily to 100 and beyond.
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Beyond My Wildest Expectations
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Outlive
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When Dr. Michael Greger, founder of NutritionFacts.org, dove into the top peer-reviewed anti-aging medical research, he realized that diet could regulate every one of the most promising strategies for combating the effects of aging. We don’t need Big Pharma to keep us feeling young—we already have the tools. In How Not to Age, the internationally renowned physician and nutritionist breaks down the science of aging and chronic illness and explains how to help avoid the diseases most commonly encountered in our journeys through life.
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Where is the "accompanying pdf"
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Age Later
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How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel 50 through your 80s and 90s? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases.
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Hang on, help is coming!
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Why We Sleep
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Sleep is one of the most important but least understood aspects of our life, wellness, and longevity. Until very recently, science had no answer to the question of why we sleep, or what good it served, or why we suffer such devastating health consequences when we don't sleep. Compared to the other basic drives in life - eating, drinking, and reproducing - the purpose of sleep remained elusive.
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I recommend this to EVERYONE
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A Crack in Creation
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
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The Telomere Effect
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Have you wondered why some 60-year-olds look and feel like 40-year-olds and why some 40-year-olds look and feel like 60-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection.
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I expected so much more
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How Not to Die
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The vast majority of premature deaths can be prevented through simple changes in diet and lifestyle. In How Not to Die, Dr. Michael Greger, the internationally-renowned nutrition expert, physician, and founder of NutritionFacts.org, examines the fifteen top causes of premature death in America-heart disease, various cancers, diabetes, Parkinson's, high blood pressure, and more-and explains how nutritional and lifestyle interventions can sometimes trump prescription pills and other pharmaceutical and surgical approaches, freeing us to live healthier lives.
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A stunningly important book
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Breath
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There is nothing more essential to our health and well-being than breathing. Yet, as a species, humans have lost the ability to breathe correctly, with grave consequences. Journalist James Nestor travels the world to figure out what went wrong and how to fix it. The answers aren’t found in pulmonology labs, as we might expect, but in the muddy digs of ancient burial sites, secret Soviet facilities, New Jersey choir schools, and the smoggy streets of São Paulo. Nestor tracks down men and women exploring the hidden science behind ancient breathing practices.
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Does NOT coincide with Book text
- De FamAzz en 07-13-20
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Ageless
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- De: Andrew Steele
- Narrado por: Andrew Steele
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Aging - not cancer, not heart disease - is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: There are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are.
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General overview of aging and aging research
- De RealWoman8 en 03-31-21
De: Andrew Steele
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Boundless: Upgrade Your Brain, Optimize Your Body & Defy Aging
- De: Ben Greenfield
- Narrado por: James Newcomb
- Duración: 41 h y 19 m
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What if the ability to look, feel, and perform at peak capacity wasn’t the stuff of lore but instead was within easy reach? In Boundless, the New York Times best-selling author of Beyond Training and health and fitness leader Ben Greenfield offers a first-of-its-kind blueprint for total human optimization. Boundless guides you every step of the way to becoming an expert in what makes your brain tick, your body work, and your spirit happy.
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voice is dull
- De Darla Eaves en 02-27-20
De: Ben Greenfield
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Forever Strong
- A New, Science-Based Strategy for Aging Well
- De: Dr. Gabrielle Lyon
- Narrado por: Dr. Gabrielle Lyon
- Duración: 9 h y 45 m
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After years of watching patients cycle through her practice, Dr. Gabrielle Lyon noticed a pattern. While her patients struggled with a wide range of conditions, they all suffered from the same core problem: they had too little muscle rather than too much fat.
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Motivational
- De K. J. Weidenbach en 10-19-23
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The Diet Myth
- Why the Secret to Health and Weight Loss Is Already in Your Gut
- De: Tim Spector
- Narrado por: Gildart Jackson
- Duración: 12 h y 45 m
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Narración:
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What should we eat? It's a simple and fundamental question that still bewilders us despite a seemingly infinite amount of available information on which foods are best for our bodies. Scientists, dieticians, and even governments regularly publish research on the dangers of too much fat and sugar as well as on the benefits of exercise, and yet the global obesity crisis is only worsening. Most diet plans prove to be only short-term solutions, and few strategies work for everyone.
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Do not waste your credit
- De Judy en 01-22-16
De: Tim Spector
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The Truest Thing About You
- Identity, Desire, and Why It All Matters
- De: David Lomas, D. R. Jacobsen
- Narrado por: Kirby Heyborne
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General
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There are true things about us and there are truer things. David Lomas invites readers to move beyond what may simply be true to the truest thing, discovering a real identity in Christ. We are all bundles of competing desires and half-true labels. We arry them around like scars; we carry them around like badges. They tell us we are no more than a job description, relationship status, or appearance. But the most important and truest identity of every Christian is that they are loved, accepted, and created in the image of God.
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Absolute gold! Stick with it!
- De Anonymous User en 01-07-23
De: David Lomas, y otros
Lo que los oyentes dicen sobre Lifespan
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- Jules
- 09-11-19
PDF?
I don't see where we get the PDF the author keeps referring to. Please advise me.
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esto le resultó útil a 71 personas
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- Mike
- 09-19-19
Great listen, but a little preachy.
this is a great book that delivers a tremendous amount of information about the state of Aging research and life extension. it is read by the author with excerpts between the main chapters that include discussions between him and the Ghost Writer he hired to help him.
my only hang up with the book is that the author uses it to promote is political and social viewpoints. I don't blame him entirely but I do not necessarily agree with his politics so I found it to detract from the experience.
all that being said, I would highly recommend this book to anybody interested in living a longer healthier life.
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esto le resultó útil a 49 personas
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- Jake
- 10-11-20
A very insightful book, bizarre, unrelated ending.
The first 75% book is exactly what you're thinking it is - a book about aging and the current evidence about the aging and anti-aging process. The last 25% is, as others have mentioned, a completely bizarre, unrelated addition that should have been left out of this book. While the initial conclusions at the end are reasonable (what would this mean for healthcare if people are living to 200+ years old), the rest of it completely unrelated (we shouldn't prolong life just yet because republicans just need to die off so that people can vote democrat, which is the true, morally correct option). You would think a scientist would be able to separate himself from this, but no. The end takes away from what would otherwise be a great summary of the current literature.
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esto le resultó útil a 2 personas
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- Amazon Customer
- 08-05-20
Fascinating
it really makes you wonder about a world where people live hundreds of years in good health
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- Weezleheadjr
- 09-26-19
this book is an absolute MUST READ
this book is an absolute MUST READ. download it now ! I am extremely sad that it is over
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- B
- 05-02-20
Great Book
Informative with actionable data, personal stories and ethical constructs. Bought the hard copy as well to use as a quick reference down the line. The short conversations between chapters are also a nice touch. Excellent book to listen to on the treadmill. Thank you for writing and narrating! Keep up the great work!
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- Holbywan
- 09-22-19
Dr. Sinclair would make a GREAT dinner guest.
There is no question that this Aussie Dr. is a complete badass. I first heard him speak during a podcast with Dr. Attia and I knew that I had to learn more from him. And, it just so happens that he released his book. SO, I bought it, DEVOURED it and honestly, I want more. This book breaks it all down. Down to the very basic bio-chemical processes and biological processes that control, speed up or slow down AGING. An incredible read and re-read, as I'm going to have to review a few of the early chapters. Thank you Dr. Sinclair for spending your life figuring out how to life a HEALTHY life.
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- JoAn K.
- 04-25-20
Wonderfully inspiring study!
What a wonderfully inspiring study! Thank you to David Sinclair and Matthew LaPlante for opening marvelous possibilities for us. Hearing knowledgeable experts present us with life’s very real possibilities is beyond thrilling. Thank you for revealing that the future CAN be brilliant and each one of us is responsible for taking charge to create that brilliant future. These authors inspire me to get to work to create that desirable experience that hopefully will be our tomorrows.
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- Carina Paraiso
- 06-27-20
Beautiful
What a rollercoaster! So many mixed emotions while reading this book. I never felt so conflicted between wanting to live longer and not even wanting to get to my 80's. Professor Sinclair describes personal experiences in such a way that we can relate to it and describes several scientific experiments in a simple, understandable way. Although, there are quite a few technical names that for someone with no Biology background might be confusing it's a fantastic journey into longevity research and on how society approaches aging. Eye-opening and encouraging reading! There's already so much we can do that is proven to give us a few extra HEALTHY years. I absolutely recommend this book.
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- Tonya Brown
- 06-20-20
Great book!
Enjoyed listening to this book! Very informative. It definitely provided food for thought. Information like this is valuable during this time. Will listen to it again.
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