
The Genesis Machine
Our Quest to Rewrite Life in the Age of Synthetic Biology
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Narrado por:
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Amy Webb
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Andrew Hessel
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Tim Campbell
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Landon Woodson
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Amanda Dolan
Acerca de esta escucha
What if the miracle that created mRNA vaccines is less a once-in-lifetime event and more the harbinger of the emerging age of synthetic biology? This fusion of biology and computers has a singular goal: to gain access to cells in order to write new—and possibly better—biological code.
Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves. Soon, we will program living, biological structures as though they were tiny computers.
But who should decide how to engineer living organisms? Whether engineered organisms should be planted, farmed, and released into the wild? Should there be limits to human enhancements? Amy Webb and Andrew Hessel’s riveting examination of synthetic biology and the bioeconomy provide the background for thinking through the upcoming risks and moral dilemmas posed by redesigning life, as well as the vast opportunities waiting for us on the horizon.
©2022 Amy Webb and Andrew Hessel (P)2022 PublicAffairsLos oyentes también disfrutaron...
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Short and unfocused, but often quite interesting.
- De Alan en 06-23-10
De: Spencer Wells
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Whiplash
- How to Survive Our Faster Future
- De: Joi Ito, Jeff Howe
- Narrado por: James Foster
- Duración: 7 h y 48 m
- Versión completa
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Today, not only is everything digital getting faster, cheaper, and smaller at an exponential rate, we also have the Internet. When these two revolutions - one in technology and the other in communications - joined, an explosive force was unleashed that changed the very nature of innovation. And with any change, we have seen many strategic blunders and extraordinary learning curves along the way.
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Just general advice on how to survive
- De A. Yoshida en 09-01-17
De: Joi Ito, y otros
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Resilience
- Why Things Bounce Back
- De: Andrew Zolli, Ann Marie Healy
- Narrado por: Sean Runnette
- Duración: 11 h y 8 m
- Versión completa
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Historia
Katrina. Haiti. BP. Fukushima. The Great Recession. Those are just a few of the catastrophic disruptions the world has endured in recent years. As we try to respond to such crises, key questions arise: What causes one system to break under great stress and another to rebound? How much change can a complex system absorb while still retaining its purpose and function? What characteristics make it adaptive to change? Provocative and eye-opening, Resilience sheds light on the nature of change.
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Totally Misleading Title
- De Doug en 07-18-12
De: Andrew Zolli, y otros
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Creation
- How Science Is Reinventing Life Itself
- De: Adam Rutherford
- Narrado por: Walter Dixon
- Duración: 6 h y 53 m
- Versión completa
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What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.
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The Goldilocks book on what is life
- De Gary en 07-11-13
De: Adam Rutherford
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Rigor Mortis
- How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions
- De: Richard Harris
- Narrado por: Joe Delafield
- Duración: 5 h y 56 m
- Versión completa
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American taxpayers spend $30 billion annually funding biomedical research, but over half of these studies can't be replicated due to poor experimental design, improper methods, and sloppy statistics. Bad science doesn't just hold back medical progress, it can sign the equivalent of a death sentence for terminal patients. In Rigor Mortis, Richard Harris explores these urgent issues with vivid anecdotes, personal stories, and interviews with the top biomedical researchers. We need to fix our dysfunctional biomedical system - before it's too late.
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Eye opening introduction to biomedical R&D
- De Amazon Customer en 09-18-18
De: Richard Harris
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Know This
- Today's Most Interesting and Important Scientific Ideas, Discoveries, and Developments
- De: John Brockman
- Narrado por: Gabra Zackman, Dan John Miller
- Duración: 14 h y 39 m
- Versión completa
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Historia
Scientific developments radically alter our understanding of the world. Whether it's technology, climate change, health research, or the latest revelations of neuroscience, physics, or psychology, science has, as Edge editor John Brockman says, "become a big story, if not the big story". In that spirit this new addition to Edge.org's fascinating series asks a powerful and provocative question: What do you consider the most interesting and important recent scientific news?
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Pete and Repeat and Re-repeat
- De Daniel L en 02-25-18
De: John Brockman
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Influenza
- The Hundred-Year Hunt to Cure the 1918 Spanish Flu Pandemic
- De: Dr. Jeremy Brown
- Narrado por: Holter Graham
- Duración: 6 h y 28 m
- Versión completa
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Historia
On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?
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Important read
- De Kathryn C. en 12-21-18
De: Dr. Jeremy Brown
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Poison Spring
- The Secret History of Pollution and the EPA
- De: E. G. Vallianatos, McKay Jenkins
- Narrado por: Michael McConnahie
- Duración: 9 h y 47 m
- Versión completa
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Historia
Imagine walking into a restaurant and finding chlorinated hydrocarbon pesticides, or neonicotinoid insecticides listed in the description of your entree. They may not be printed in the menu, but many are in your food.These are a few of the literally millions of pounds of approved synthetic substances dumped into the environment every day, not just in the US but around the world.
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A Frightening Wake Up Call!
- De Exec. Chef 'Special K' en 07-02-14
De: E. G. Vallianatos, y otros
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p53: The Gene That Cracked the Cancer Code
- De: Sue Armstrong
- Narrado por: Elizabeth Jasicki
- Duración: 9 h y 55 m
- Versión completa
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- De Adriana en 12-25-14
De: Sue Armstrong
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The Secret History of the War on Cancer
- De: Devra Davis Ph.D.
- Narrado por: Pam Ward
- Duración: 19 h y 11 m
- Versión completa
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The War on Cancer was run by leaders of industries that made cancer-causing products and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies, a legacy that persists to this day.
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Silly Book
- De Adam Smith en 12-24-14
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Jump-Starting America
- How Breakthrough Science Can Revive Economic Growth and the American Dream
- De: Jonathan Gruber, Simon Johnson
- Narrado por: Robert Fass
- Duración: 9 h y 57 m
- Versión completa
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Historia
The untold story of how America once created the most successful economy the world has ever seen and how we can do it again.
De: Jonathan Gruber, y otros
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Data-ism
- The Revolution Transforming Decision Making, Consumer Behavior, and Almost Everything Else
- De: Steve Lohr
- Narrado por: Steve Lohr
- Duración: 6 h y 33 m
- Versión completa
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Coal, iron ore, and oil were the key productive assets that fueled the Industrial Revolution. Today data is the vital raw material of the information economy. The explosive abundance of this digital asset, more than doubling every two years, is creating a new world of opportunity and challenge. Data-ism is about this next phase, in which vast, Internet-scale data sets are used for discovery and prediction in virtually every field. It is a journey across this emerging world with people, illuminating narrative examples, and insights.
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More business case than serious analysis
- De Godfried Gubbels en 06-03-15
De: Steve Lohr
Las personas que vieron esto también vieron...
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The Big Nine
- How the Tech Titans and Their Thinking Machines Could Warp Humanity
- De: Amy Webb
- Narrado por: Amanda Dolan
- Duración: 9 h y 35 m
- Versión completa
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General
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Narración:
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Historia
In this book, Amy Webb reveals the pervasive, invisible ways in which the foundations of AI - the people working on the system, their motivations, the technology itself - is broken. Within our lifetimes, AI will, by design, begin to behave unpredictably, thinking and acting in ways which defy human logic. The big nine corporations may be inadvertently building and enabling vast arrays of intelligent systems that don't share our motivations, desires, or hopes for the future of humanity.
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Interesting but Frustrating
- De Kathy en 03-26-19
De: Amy Webb
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The Signals Are Talking
- De: Amy Webb
- Narrado por: Tiffany Morgan
- Duración: 10 h y 28 m
- Versión completa
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General
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Narración:
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Historia
How do you tell a real trend from the merely trendy? How, for example, will a technology—like artificial intelligence, machine learning, self-driving cars, biohacking, bots, and the Internet of Things—affect us, our businesses, and workplaces? How will it eventually change the way we live, work, play, and think—and how should we prepare for it now? In The Signals Are Talking, noted futurist Amy Webb shows us how to analyze the "true signals" and land on the right side of disruption.
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Good book, awful narrator
- De Chelsea en 08-09-18
De: Amy Webb
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Data, A Love Story
- How I Gamed Online Dating to Meet My Match
- De: Amy Webb
- Narrado por: Amy Webb, Brian Woolf
- Duración: 8 h y 39 m
- Versión completa
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General
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Narración:
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Historia
After yet another online dating disaster, Amy Webb was about to cancel her JDate membership when an epiphany struck: It wasn’t that her standards were too high, as women are often told, but that she wasn’t evaluating the right data in suitors’ profiles. That night Webb, an award-winning journalist and digital-strategy expert, made a detailed, exhaustive list of what she did and didn’t want in a mate.
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Fun story, but not a how-to
- De Lisa en 02-20-13
De: Amy Webb
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Regenesis
- How Synthetic Biology Will Reinvent Nature and Ourselves
- De: George M. Church, Ed Regis
- Narrado por: Peter Lerman
- Duración: 10 h y 47 m
- Versión completa
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General
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Narración:
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Historia
In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.
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Brilliant! But please update!
- De Nick en 01-28-21
De: George M. Church, y otros
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- De: Jennifer A. Doudna, Samuel H. Sternberg
- Narrado por: Erin Bennett
- Duración: 9 h y 22 m
- Versión completa
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General
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Narración:
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Historia
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- De Philomath en 06-17-17
De: Jennifer A. Doudna, y otros
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Hacking Darwin
- Genetic Engineering and the Future of Humanity
- De: Jamie Metzl
- Narrado por: Eric Martin
- Duración: 10 h y 58 m
- Versión completa
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General
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Narración:
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Historia
From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.
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Technology Overview - Good; Policy Discussion - No
- De sct en 05-18-19
De: Jamie Metzl
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The Big Nine
- How the Tech Titans and Their Thinking Machines Could Warp Humanity
- De: Amy Webb
- Narrado por: Amanda Dolan
- Duración: 9 h y 35 m
- Versión completa
-
General
-
Narración:
-
Historia
In this book, Amy Webb reveals the pervasive, invisible ways in which the foundations of AI - the people working on the system, their motivations, the technology itself - is broken. Within our lifetimes, AI will, by design, begin to behave unpredictably, thinking and acting in ways which defy human logic. The big nine corporations may be inadvertently building and enabling vast arrays of intelligent systems that don't share our motivations, desires, or hopes for the future of humanity.
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Interesting but Frustrating
- De Kathy en 03-26-19
De: Amy Webb
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The Signals Are Talking
- De: Amy Webb
- Narrado por: Tiffany Morgan
- Duración: 10 h y 28 m
- Versión completa
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General
-
Narración:
-
Historia
How do you tell a real trend from the merely trendy? How, for example, will a technology—like artificial intelligence, machine learning, self-driving cars, biohacking, bots, and the Internet of Things—affect us, our businesses, and workplaces? How will it eventually change the way we live, work, play, and think—and how should we prepare for it now? In The Signals Are Talking, noted futurist Amy Webb shows us how to analyze the "true signals" and land on the right side of disruption.
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Good book, awful narrator
- De Chelsea en 08-09-18
De: Amy Webb
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Data, A Love Story
- How I Gamed Online Dating to Meet My Match
- De: Amy Webb
- Narrado por: Amy Webb, Brian Woolf
- Duración: 8 h y 39 m
- Versión completa
-
General
-
Narración:
-
Historia
After yet another online dating disaster, Amy Webb was about to cancel her JDate membership when an epiphany struck: It wasn’t that her standards were too high, as women are often told, but that she wasn’t evaluating the right data in suitors’ profiles. That night Webb, an award-winning journalist and digital-strategy expert, made a detailed, exhaustive list of what she did and didn’t want in a mate.
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Fun story, but not a how-to
- De Lisa en 02-20-13
De: Amy Webb
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Regenesis
- How Synthetic Biology Will Reinvent Nature and Ourselves
- De: George M. Church, Ed Regis
- Narrado por: Peter Lerman
- Duración: 10 h y 47 m
- Versión completa
-
General
-
Narración:
-
Historia
In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.
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Brilliant! But please update!
- De Nick en 01-28-21
De: George M. Church, y otros
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- De: Jennifer A. Doudna, Samuel H. Sternberg
- Narrado por: Erin Bennett
- Duración: 9 h y 22 m
- Versión completa
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General
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Narración:
-
Historia
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
-
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In to the abyss we ascend, a scary future
- De Philomath en 06-17-17
De: Jennifer A. Doudna, y otros
-
Hacking Darwin
- Genetic Engineering and the Future of Humanity
- De: Jamie Metzl
- Narrado por: Eric Martin
- Duración: 10 h y 58 m
- Versión completa
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General
-
Narración:
-
Historia
From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.
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Technology Overview - Good; Policy Discussion - No
- De sct en 05-18-19
De: Jamie Metzl
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The Code Breaker
- Jennifer Doudna, Gene Editing, and the Future of the Human Race
- De: Walter Isaacson
- Narrado por: Kathe Mazur, Walter Isaacson
- Duración: 16 h y 4 m
- Versión completa
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General
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Historia
The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
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Except for the author, this book is good!
- De Johan en 03-14-21
De: Walter Isaacson
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Superconvergence
- How the Genetics, Biotech, and AI Revolutions Will Transform our Lives, Work, and World
- De: Jamie Metzl
- Narrado por: James Anderson Foster, Jamie Metzl
- Duración: 15 h y 44 m
- Versión completa
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General
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Historia
Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.
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Great Book Somewhat Spoiled by Self-Promotion
- De Jack E. Koepke en 06-22-24
De: Jamie Metzl
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The Future Is Faster Than You Think
- How Converging Technologies Are Disrupting Business, Industries, and Our Lives
- De: Peter H. Diamandis, Steven Kotler
- Narrado por: Peter H. Diamandis
- Duración: 9 h y 53 m
- Versión completa
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Historia
In their book Abundance, best-selling authors and futurists Peter Diamandis and Steven Kotler tackled grand global challenges, such as poverty, hunger, and energy. Then, in Bold, they chronicled the use of exponential technologies that allowed the emergence of powerful new entrepreneurs. Now the best-selling authors are back with The Future Is Faster Than You Think, a blueprint for how our world will change in response to the next 10 years of rapid technological disruption.
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Totally Mixed on This One
- De D. Sooley en 02-03-20
De: Peter H. Diamandis, y otros
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The Song of the Cell
- An Exploration of Medicine and the New Human
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 16 h y 3 m
- Versión completa
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Historia
From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.
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Beyond Words Wonderful
- De Lynn en 11-27-22
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The Singularity Is Near
- When Humans Transcend Biology
- De: Ray Kurzweil
- Narrado por: George Wilson
- Duración: 24 h y 38 m
- Versión completa
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Narración:
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Historia
For over three decades, Ray Kurzweil has been one of the most respected and provocative advocates of the role of technology in our future. In his classic The Age of Spiritual Machines, he argued that computers would soon rival the full range of human intelligence at its best. Now he examines the next step in this inexorable evolutionary process: The union of human and machine, in which the knowledge and skills embedded in our brains will be combined with the vastly greater capacity, speed, and knowledge-sharing ability of our creations.
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RUINED audio.
- De Fred en 06-25-21
De: Ray Kurzweil
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Co-Intelligence
- Living and Working with AI
- De: Ethan Mollick
- Narrado por: Ethan Mollick
- Duración: 4 h y 39 m
- Versión completa
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General
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Historia
Something new entered our world in November 2022—the first general purpose AI that could pass for a human and do the kinds of creative, innovative work that only humans could do previously. Wharton professor Ethan Mollick immediately understood what ChatGPT meant: after millions of years on our own, humans had developed a kind of co-intelligence that could augment, or even replace, human thinking. Through his writing, speaking, and teaching, Mollick has become one of the most prominent and provocative explainers of AI.
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great intro book marred by poor narration
- De Amazon Customer en 04-14-24
De: Ethan Mollick
Lo que los oyentes dicen sobre The Genesis Machine
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- Jennifer Thomas
- 01-10-25
Fascinating
this is fascinating and inspiring review of bio engineering with substantial commentary as to possible future outcomes. The book is highly educational and didactic, and it is designed to be highly accessible (not too technical) the authors' sense of excitement and inspiration and passion for the topic is rather contagious and it will inspire you to think about a possible better future with the use of synthetic biology. Whether you are against or for genetic engineering this book is chalk full of examples stories and ideas that will fascinate. I would particularly recommend it for someone who is against GMO's because I think that they accessible scientific information might inform their views.
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- John D. Furber
- 04-16-22
Mostly accurate, worthwhile, informative
A comprehensive exploration of this important field. The authors got most of the facts right. The readers were good, easy to listen to. Only mispronounced a few technical terms. But if you have to choose only one, I recommend "The Code Breaker" by Walter Isaacson, about CRISPR and Jennifer Doudna.
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- Brian Garrett
- 05-17-22
The future is going to be crazy
Definitely lots of very interesting vectors the biological future is going to be taking. I'm hoping that some of the items they are working on are going to have a direct benefit to my longevity, but I'm afraid it's going to happen slightly slower than I want it to. Of course the darker side of this is the "dark science" that could be used in a negative way on humanity. Definitely a good read IMHO.
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- Rockin' Horse
- 03-11-22
A Warning
This book contains science surveyed without an agenda. It can be scary to hear facts
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- Andy
- 07-02-22
Thought provoking but politically biased
Very thought provoking and worth reading. The text lacks some level of detail to support its claims but does offer some broad brush speculations. Readers should be aware of obvious left wing political bias throughout the text, painting a less than balanced picture of events as well as obviously biased views of potential futures.
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- J
- 02-21-22
Great book on the possibilities of the future of Human biology
Preordered this a few months back because I’ve enjoy the previous works of Amy Webb. I’m in the tech industry but haven’t had any exposure to biological sciences since college about 10 years ago. The scenarios laid out may seem outlandish but if you see the real world examples cited throughout the book then they begin to seem plausible and realistic. The narrator did a great job and definitely recommend anyone to take a listen to it if they’re willing to have an open mind.
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- Rupert
- 04-17-22
Frightening
Evolution continues while some contemplates if it's true. There are the applications of so many methods within our universe yet we continue to think of God as a magician.
Thank you Amy and Andrew. And let's hail the TWIT audience, heard about this there.
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- Austin
- 05-24-22
Really good synthesis of the field with an informed perspective; bad solutions
The first 90% of the book was really great! Really informative history including even recent advancements in synthetic biology. The last 10% with their solutions leave a lot to be desired. They softly peddle the “COVID was a made in a Chinese lab” conspiracy to argue against gain-of-function research. That left a really bad taste in my mouth. Their other “solutions” were a bit oversimplistic.
However, the first 90% of the book, especially the scenarios toward the end, make it worth it.
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- Taylor Ono
- 03-21-22
An optimistic look at a terrifying future
The parts that actually focus on synthetic biology are very interesting but at many points the authors lose focus and wander off on tangents. Will definitely spend some time seeing if there is a better book on the subject
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- Anonymous
- 06-19-23
The book we need, but not the book we deserve
The intro and conclusion are the best parts because the main idea is stated. This book addresses a lot of important future issues. Unfortunately, it spends many hours meandering around the big ideas. This is both a must-read primer for all global citizens who will live to see the genesis machine take over, and also a bit of a disappointment.
6/10, Would Recommend
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