The Epigenetics Revolution
How Modern Biology Is Rewriting Our Understanding of Genetics, Disease and Inheritance
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Narrado por:
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Donna Postel
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De:
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Nessa Carey
Acerca de esta escucha
Nessa Carey’s The Epigenetics Revolution looks at how modern biology is rewriting our understanding of genetics, disease and inheritance.
At the beginning of this century, enormous progress had been made in genetics. The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us we still don't even know all the questions. The Epigenetics Revolution traces the thrilling path that epigenetics has taken over the last 20 years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees control their colonies, why tortoiseshell cats are always female and why we age, develop disease and become addicted to drugs. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all.
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Narración:4.5 out of 5 stars 101
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Historia4.5 out of 5 stars 101
Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?
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3 out of 5 stars
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Fascinating Biology ; Distracting Narration
- De Tim en 03-01-15
De: Jamie A. Davies
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Evolving Ourselves
- How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth
- De: Juan Enriquez, Steve Gullans
- Narrado por: Rob Shapiro
- Duración: 10 h y 50 m
- Versión completa
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General4.5 out of 5 stars 205
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Narración:4.5 out of 5 stars 179
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Historia4.5 out of 5 stars 182
Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?
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5 out of 5 stars
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fascinating ideas and science
- De Joel en 07-04-15
De: Juan Enriquez, y otros
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- De: Rob DeSalle, Susan L. Perkins
- Narrado por: Stephen McLaughlin
- Duración: 7 h y 25 m
- Versión completa
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General4.5 out of 5 stars 36
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Narración:4.5 out of 5 stars 35
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Historia4.5 out of 5 stars 34
Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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5 out of 5 stars
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I learned so much from this book. I am happy.
- De Jonathan Miller en 09-08-18
De: Rob DeSalle, y otros
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- De: Daniel M. Davis
- Narrado por: Christopher Grove
- Duración: 7 h y 48 m
- Versión completa
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General4.5 out of 5 stars 53
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Narración:4.5 out of 5 stars 43
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Historia4.5 out of 5 stars 43
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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5 out of 5 stars
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If interested in medicine, got to read
- De Howard Sterling en 06-29-16
De: Daniel M. Davis
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The Gene
- An Intimate History
- De: Siddhartha Mukherjee
- Narrado por: Dennis Boutsikaris
- Duración: 19 h y 22 m
- Versión completa
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General4.5 out of 5 stars 5,913
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Narración:4.5 out of 5 stars 5,185
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Historia4.5 out of 5 stars 5,138
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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5 out of 5 stars
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It's a Wonderful Book
- De JKC en 06-02-16
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Human Errors
- A Panorama of Our Glitches, from Pointless Bones to Broken Genes
- De: Nathan H. Lents
- Narrado por: L.J. Ganser
- Duración: 7 h y 54 m
- Versión completa
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General4.5 out of 5 stars 2,277
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Narración:4.5 out of 5 stars 2,003
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Historia4.5 out of 5 stars 1,998
We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.
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4 out of 5 stars
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From Pointless Bones to Broken Genes to...Aliens?
- De Katy.LED en 12-04-18
De: Nathan H. Lents
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- De: Francis S. Collins
- Narrado por: Greg Itzin
- Duración: 10 h y 45 m
- Versión completa
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General4 out of 5 stars 148
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Narración:4.5 out of 5 stars 99
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Historia4 out of 5 stars 98
A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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5 out of 5 stars
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The future of medicine
- De Ronald E en 04-12-10
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- De: Jennifer A. Doudna, Samuel H. Sternberg
- Narrado por: Erin Bennett
- Duración: 9 h y 22 m
- Versión completa
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General4.5 out of 5 stars 1,367
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Narración:4.5 out of 5 stars 1,169
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Historia4.5 out of 5 stars 1,168
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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5 out of 5 stars
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In to the abyss we ascend, a scary future
- De Philomath en 06-17-17
De: Jennifer A. Doudna, y otros
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p53: The Gene That Cracked the Cancer Code
- De: Sue Armstrong
- Narrado por: Elizabeth Jasicki
- Duración: 9 h y 55 m
- Versión completa
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General4.5 out of 5 stars 125
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Narración:4 out of 5 stars 109
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Historia4.5 out of 5 stars 107
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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5 out of 5 stars
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Excellent story! Unfortunate narration at start
- De Adriana en 12-25-14
De: Sue Armstrong
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- De: Kat Arney
- Narrado por: Kat Arney
- Duración: 8 h y 39 m
- Versión completa
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General4.5 out of 5 stars 53
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Narración:4.5 out of 5 stars 47
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Historia4.5 out of 5 stars 46
The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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2 out of 5 stars
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A non-scientists misguided interpretation
- De AraSevera en 05-15-16
De: Kat Arney
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- De: Moises Velasquez-Manoff
- Narrado por: Chris Sorensen
- Duración: 17 h y 6 m
- Versión completa
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General4.5 out of 5 stars 55
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Narración:4.5 out of 5 stars 48
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Historia4.5 out of 5 stars 49
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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5 out of 5 stars
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The point of view from a Veterinarian immunologist
- De rtgymnast en 11-03-17
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- De: Leonardo Trasande MD MPP
- Narrado por: Leonardo Trasande MD MPP
- Duración: 6 h y 44 m
- Versión completa
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General4.5 out of 5 stars 45
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Narración:4.5 out of 5 stars 38
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Historia4.5 out of 5 stars 38
Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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5 out of 5 stars
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The Must Read Book of 2019 is here early on Audio!
- De Ryan S en 12-21-18
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The Vital Question
- Energy, Evolution, and the Origins of Complex Life
- De: Nick Lane
- Narrado por: Kevin Pariseau
- Duración: 11 h y 27 m
- Versión completa
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General4.5 out of 5 stars 1,183
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Narración:4.5 out of 5 stars 1,046
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Historia4.5 out of 5 stars 1,035
The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.
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4 out of 5 stars
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Ouch!
- De Mark en 06-24-16
De: Nick Lane
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Missing Microbes
- How the Overuse of Antibiotics Is Fueling Our Modern Plagues
- De: Martin J. Blaser
- Narrado por: Patrick Lawlor
- Duración: 8 h y 43 m
- Versión completa
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General4.5 out of 5 stars 385
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Narración:4.5 out of 5 stars 328
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Historia4.5 out of 5 stars 330
In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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5 out of 5 stars
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Very enlightening and information well supported
- De James en 05-03-15
De: Martin J. Blaser
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- De: George Johnson
- Narrado por: Arthur Morey
- Duración: 8 h y 19 m
- Versión completa
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General4.5 out of 5 stars 63
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Narración:4.5 out of 5 stars 54
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Historia4.5 out of 5 stars 54
When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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5 out of 5 stars
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A quick read - hard to put down
- De Digital Dilema en 09-06-13
De: George Johnson
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Creation
- How Science Is Reinventing Life Itself
- De: Adam Rutherford
- Narrado por: Walter Dixon
- Duración: 6 h y 53 m
- Versión completa
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General4 out of 5 stars 44
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Narración:4 out of 5 stars 43
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Historia4 out of 5 stars 43
What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.
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5 out of 5 stars
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The Goldilocks book on what is life
- De Gary en 07-11-13
De: Adam Rutherford
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The Accidental Mind
- How Brain Evolution Has Given Us Love, Memory, Dreams, and God
- De: David J. Linden
- Narrado por: Ray Porter
- Duración: 7 h y 56 m
- Versión completa
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General4 out of 5 stars 320
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Narración:4 out of 5 stars 210
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Historia4 out of 5 stars 209
You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.
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5 out of 5 stars
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Best general-public Brain Science book to date
- De Francisco en 02-14-11
De: David J. Linden