
The Catalyst
RNA and the Quest to Unlock Life's Deepest Secrets
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Narrado por:
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Joshua Saxon
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De:
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Thomas R. Cech
Acerca de esta escucha
For over half a century, DNA has dominated science and the popular imagination as the "secret of life." But over the last several decades, a quiet revolution has taken place. In a series of breathtaking discoveries, the biochemist Thomas R. Cech and a diverse cast of brilliant scientists have revealed that RNA-long overlooked as the passive servant of DNA-sits at the center of biology's greatest mysteries: How did life begin? What makes us human? Why do we get sick and grow old? In The Catalyst, Cech finally brings together years of research to demonstrate that RNA is the true key to understanding life on Earth, from its very origins to our future in the twenty-first century.
A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health. We learn how RNA may have jump-started life itself, and how, at the same time, it can cut our individual lives short through viral diseases and cancer. We see how RNA is implicated in the aging process and explore the darker depths of the supposed fountain of youth, telomerase. And we catch a thrilling glimpse into how RNA-powered therapies may enable us to improve and even extend life beyond nature's current limits.
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- De Srikanth Ramanujam en 11-15-18
De: Marty Cagan
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My Big TOE: Discovery
- Book Two of a Trilogy Unifying Philosophy, Physics, and Metaphysics
- De: Thomas Campbell
- Narrado por: Thomas Campbell
- Duración: 15 h y 25 m
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Section 3 develops the interface and interaction between we the people and our digital consciousness reality. It derives and explains the characteristics, origins, dynamics, and function of ego, love, and free will. It derives our larger purpose. Finally, Section 3 develops the psi uncertainty principle as it explains and interrelates psi phenomena, free will, love, consciousness evolution, reality, human purpose, entropy and physics.
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A guidebook to a bigger reality & realization
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Letters from an Astrophysicist
- De: Neil deGrasse Tyson
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- Duración: 5 h y 35 m
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Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.
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Dear Neil...
- De Tina G. en 10-14-19
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Welcome to the Universe
- An Astrophysical Tour
- De: Michael A. Strauss, J. Richard Gott, Neil deGrasse Tyson
- Narrado por: Michael Butler Murray
- Duración: 17 h y 53 m
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Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.
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All About What We Know About the Universe - ALL
- De J.B. en 02-17-17
De: Michael A. Strauss, y otros
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The Structure of Scientific Revolutions
- De: Thomas S. Kuhn
- Narrado por: Dennis Holland
- Duración: 10 h y 14 m
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A good book may have the power to change the way we see the world, but a great book actually becomes part of our daily consciousness, pervading our thinking to the point that we take it for granted, and we forget how provocative and challenging its ideas once were - and still are. The Structure of Scientific Revolutions is that kind of book.
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The problem is not with the book
- De Marcus en 08-09-09
De: Thomas S. Kuhn
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The Theory of Everything: The Quest to Explain All Reality
- De: Don Lincoln, The Great Courses
- Narrado por: Don Lincoln
- Duración: 12 h y 21 m
- Grabación Original
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At the end of his career, Albert Einstein was pursuing a dream far more ambitious than the theory of relativity. He was trying to find an equation that explained all physical reality - a theory of everything. Experimental physicist and award-winning educator Dr. Don Lincoln takes you on this exciting journey in The Theory of Everything: The Quest to Explain All Reality. Suitable for the intellectually curious at all levels and assuming no background beyond basic high-school math, these 24 half-hour lectures cover recent developments at the forefront of particle physics and cosmology.
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Audible’s Best Science Offering, A Gem
- De MikeB en 12-08-18
De: Don Lincoln, y otros
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Impossible Monsters reveals the central role of dinosaurs and their discovery in toppling traditional religious authority, and in changing perceptions about the Bible, history, and mankind's place in the world.
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Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.
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biochemistry+autobiography+science politics
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How Tyrants Fall
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Meeting with a revolutionary (codename 'Satan') who risked Stasi capture to undermine an oppressive regime, an American-Gambian activist who plotted to liberate his homeland on breaks during his construction job and the unapologetic former leader of a Burundian rebel group which carried out a massacre, internationally renowned security expert and political scientist Dr Marcel Dirsus draws on extensive field research and personal interviews with coup leaders, rebels and soldiers to examine the workings and malfunctions of tyrants.
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How We Age
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All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.
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Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.
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Impossible Monsters reveals the central role of dinosaurs and their discovery in toppling traditional religious authority, and in changing perceptions about the Bible, history, and mankind's place in the world.
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Repetitive and not that interesting
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Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.
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biochemistry+autobiography+science politics
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How Tyrants Fall
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Meeting with a revolutionary (codename 'Satan') who risked Stasi capture to undermine an oppressive regime, an American-Gambian activist who plotted to liberate his homeland on breaks during his construction job and the unapologetic former leader of a Burundian rebel group which carried out a massacre, internationally renowned security expert and political scientist Dr Marcel Dirsus draws on extensive field research and personal interviews with coup leaders, rebels and soldiers to examine the workings and malfunctions of tyrants.
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Is there such a thing as a timeless classic? More than a decade ago, Rochelle Gurstein set out to explore and establish a solid foundation for the classic in the history of taste. To her surprise, that history instead revealed repeated episodes of soaring and falling reputations, rediscoveries of long-forgotten artists, and radical shifts in the canon, all of which went so completely against common knowledge that it was hard to believe it was true.
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Why has war been such a consistent presence throughout the human past? A leading historian explains, drawing on rich examples and keen insight. Richard Overy is not the first scholar to take up the title question. In 1931, at the request of the League of Nations, Albert Einstein asked Sigmund Freud to collaborate on a short work examining whether there was "a way of delivering mankind from the menace of war." Published the next year as a pamphlet entitled Why War?, it conveyed Freud's conclusion that the "death drive" made any deliverance impossible.
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War is Peace
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Life Ascending
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Where does DNA come from? What is consciousness? How did the eye evolve? Drawing on a treasure trove of new scientific knowledge, Nick Lane expertly reconstructs evolution's history by describing its 10 greatest inventions - from sex and warmth to death - resulting in a stunning account of nature's ingenuity.
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Great and informative but with prior knowledge
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In August 1945, a handful of people raised a homemade cotton flag and announced the birth of a new nation. With the fourth largest population in the world, inhabiting islands that span an eighth of the globe, Indonesia became the first country to rid itself of colonial rule after WWII.
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Spycraft
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In this engaging, accessible account, Nadine Akkerman and Pete Langman explore the methods spies actually used in the period, including disguises, invisible inks, and even poisons. Drawing on a vast array of archival sources, they show how understanding the tricks and tools of espionage allows us to reimagine well-known stories such as the Babington and Gunpowder plots.
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Needs accompanying PDF
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How Economics Explains the World
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This small book indeed tells a big story. It is the story of capitalism–of how our market system developed. It is the story of the discipline of economics, and some of the key figures who formed it. And it is the story of how economic forces have shaped world history. Why didn’t Africa colonize Europe instead of the other way around? What happened when countries erected trade and immigration barriers in the 1930s? Why did the Allies win World War II? You’ll find answers to these questions and more in How Economics Explains the World.
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Rehashed ideas better explained in other books
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Raiders, Rulers, and Traders
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No animal is so entangled in human history as the horse. The thread starts in prehistory, with a slight, shy animal, hunted for food. Domesticating the horse allowed early humans to settle the vast Eurasian steppe; later, their horses enabled new forms of warfare, encouraged long-distance trade routes, and ended up acquiring deep cultural and religious significance.
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Amazing breath of scope
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Gray Matters
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We’ve all heard the phrase “it’s not brain surgery.” But what exactly is brain surgery? It’s a profession that is barely a hundred years old and profoundly connects two human beings, but few know how it works, or its history. In this warm, rigorous, and deeply insightful book, Dr. Theodore H. Schwartz explores what it’s like to hold the scalpel, wield the drill, extract a tumor, fix a bullet hole, and remove a blood clot—when every second can mean life or death.
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The Invention of Good and Evil
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What makes us moral beings? How do we decide what is good and what is evil? And has it always been that way? Hanno Sauer's sweeping new history of humanity, covering five million years of our universal moral values, comes at a crucial moment of crisis for those values, and helps to explain how they arose—and why we need them. Modern societies are in crisis: a shared universal morality seems to be a thing of the past. Hanno Sauer explains why this appearance is deceptive: in fact, there are universal values that all people share.
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Was good until author got political
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The Catalyst
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Everyone has something they want to change. Marketers want to change their customers' minds and leaders want to change organizations. Start-ups want to change industries and nonprofits want to change the world. But change is hard. Often, we persuade and pressure and push, but nothing moves. Could there be a better way? This book takes a different approach. Successful change agents know it's not about pushing harder, or providing more information, it's about being a catalyst.
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Was this book written to change my mind from a republican to a democrat?
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Venice
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Historia
No city stirs the imagination more than Venice. From the richly ornamented palaces emerging from the waters of the Grand Canal to the dazzling sites of Piazza San Marco, visitors and residents alike sense they are entering, as fourteenth-century poet Petrarch remarked, “another world.” During the Middle Ages and Renaissance, Venice was celebrated as a model republic in an age of monarchs. In the seventeenth and eighteenth centuries, it became famous for its freewheeling lifestyle characterized by courtesans, casinos, and Carnival.
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As a resident great general summary of the history of the city
- De marco en 01-13-25
De: Dennis Romano
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Infantilised
- How Our Culture Killed Adulthood
- De: Keith J. Hayward
- Narrado por: John Sackville
- Duración: 12 h y 58 m
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Noticing society's creeping descent into infantilisation is one thing, however understanding the roots and causes of the phenomenon is not quite so easy. But in this topical and vitally important new work, cultural theorist and academic, Dr Keith Hayward, exposes the deep social, psychological and political dangers of a world characterised by denuded adult autonomy.
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A well reasoned and soundly documented thesis
- De Lee O. Stokowski en 09-21-24
De: Keith J. Hayward
Lo que los oyentes dicen sobre The Catalyst
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- Trebla
- 08-23-24
Among the best at telling the story of science
As a biology major I was aware of much that Cech covers, but with the addition of much I did not know existed about RNA. Perhaps the best part is his descriptions of the visits, talks, papers, friends that actually drive basic science- it is a team sport.
The down mark is for the speaker who just murdered too many well-known bio words- very distracting.
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- Auinash Kalsotra
- 09-16-24
Captivating
Highly accessible to non experts. A wonderful weekend read. Will recommend to high school students and teachers
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Historia
- Amazon Customer
- 08-14-24
Disappointing
Given the author’s qualifications, I was expecting something way less superficial. It’s also full of dozens of unneeded and unilluminating analogies that largely serve only as a distraction. Also annoying was the increasingly common in audiobooks disclaimer that the narration refers to illustrations/charts that are found only in the paper/e-book versions of this book, instead of actually providing a PDF of those to refer to.
The narration also was disappointing. Among other things, the narrator could’ve spent a few minutes learning how to pronounce the words he was supposed to read. Or someone who actually understood the subject matter should’ve proof-listened to the narration and insisted on corrections. And it’s not just technical/biological terms that he mispronounces. He even mispronounces La Jolla (California), as “la-HOLE-a.” A truly slipshod effort.
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- Anonymous User
- 08-22-24
Disappointing reader!!
The reading is more robotic and most of the information is needless— wish it was more direct and accurate.
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- Mom
- 07-31-24
a discredit to women scientists everywhere
I was so excited to read this book. I pre-ordered the hard copy and the audible version. Midway through chapter one I immediately stopped. I requested a refund for both books and WILL NOT read or recommend it to anyone. Thomas Cech has done a great dishonor to women scientists everywhere. He proudly discussed DNA, Watson and Crick, Kings College with NO mention of Rosalind Franklin, further proving that old, white male scientists go out of their way to discredit women in science.
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