• Proactive - Interviews for investors

  • By: Proactive
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Proactive - Interviews for investors

By: Proactive
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  • Summary

  • Welcome to the Proactive podcast channel – the destination for breaking news on growth companies and up to the minute market coverage. Here we plug you into what’s new and exciting in the world of business.
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Business & Careers Economics Personal Finance Politics & Government
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Episodes
  • Exciting updates from Apollo Minerals' projects

    Exciting updates from Apollo Minerals' projects
    Nov 21 2024
    Apollo Minerals Ltd (ASX:APO) managing director Neil Inwood talks with Proactive’s Tylah Tully about the company’s latest activities, including its exciting exploration projects in Gabon. During the interview, Inwood detailed the maiden drill program results from the Slaney Gold Project, highlighting visible gold findings and the significance of being the first modern exploration of the region in seven decades. "This is only 20 metres along trend of trenching we’ve done previously," he said, emphasising the historical high-grade gold mine's potential. Inwood also shared plans for 2024, including a partnership with a reputable drilling company and the identification of new targets based on mapping and soil geochemistry. He further discussed progress at the Crusoe Zinc-Lead Project and announced an entitlement offer to engage existing shareholders in the company’s growth. With unfinished business from the current drill program and promising new targets, Apollo Minerals is set for an exciting year ahead. #ProactiveInvestors #ApolloMinerals #ASX #GoldExploration #GabonMining #SlaneyGold #ZincLeadProjects #InvestorsUpdate #MiningNews
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    5 mins
  • Connected Minerals makes uranium breakthrough in Namibia

    Connected Minerals makes uranium breakthrough in Namibia
    Nov 21 2024
    Connected Minerals makes uranium breakthrough in Namibia
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    4 mins
  • Race Oncology advances RNA epigenetics with FTO drug discovery at Monash

    Race Oncology advances RNA epigenetics with FTO drug discovery at Monash
    Nov 21 2024
    Race Oncology Ltd (ASX:RAC, OTC:RAONF) CEO Daniel Tillett joins Proactive’s Tylah Tully to discuss the FTO drug discovery program the company has concluded at Monash University’s Fragment Platform (MFP). The program successfully identified 39 molecular candidates (‘hits’) that bind specifically to the m6A RNA demethylase protein, FTO. These findings were validated using NMR spectroscopy and surface plasmon resonance. The program leverages NMR fragment screening to discover drug-like molecules that can regulate protein activity outside the enzyme's active site, offering an alternative to traditional high-throughput screening. The identified FTO-binding chemical scaffolds create opportunities for the development of patentable, first-in-class drugs targeting the m6A RNA epigenetic pathway. RNA epigenetics dysregulation, involving proteins like FTO, is linked to various cancers and metabolic diseases. However, selective inhibition of FTO is challenging due to structural similarities with related proteins in the ALKBH family. Race’s use of Monash’s curated chemical fragment library enabled the identification of unique FTO-binding structures. Race plans a ‘hit-to-lead’ campaign to refine these fragments into lead drug candidates, focusing on improving potency, selectivity, toxicity profiles, and metabolic properties. The company is currently evaluating whether to proceed with this resource-intensive phase. #ProactiveInvestors #RaceOncology, #ASX, #RNAEpigenetics, #DrugDiscovery, #CancerTherapies, #FTOProtein, #OncologyResearch, #Biotechnology, #NMRScreening, #Epigenetics, #RNARegulation, #PharmaceuticalInnovation, #CancerDrugs, #MetabolicDiseases, #MonashUniversity, #MedicinalChemistry, #CancerResearch, #TargetedTherapies, #PatentableDrugs, #BiotechInvestment
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    4 mins

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