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THIS EPISODE:

• Summary of key points from previous episodes on Genomics
• Personalised care: Pharmacogenomics
• How to discuss genomics with your patients
• The importance and impact of genetic testing

Special thanks to our guest speakers:

Dr Pooja Dasani. Lead genomic counsellor, North Thames GMSA and Principal genetic counsellor, North East Thames regional genetics service (Great Ormond Street Hospital)

Dr Anwar Khan. GP with a Special Interest in Genomics.

SPONSOR: The Genomics mini-series was sponsored by, and co-produced with the North Thames Genomics Medicine Service. Special thanks to Shazia Mahamdallie for leading and overseeing the genomics project and team and to Anwar Khan for his incredible insights, awareness and contributions.

Useful links:

• Refer back to episode 3 on FH and CF to learn more -
• NHSE GeNOTES for Primary Care: Two-tier NHS information resource centred around clinical scenarios and encyclopaedia of further learning resources – click HERE
• NHSE Genomics National Test Directory – click HERE
• NTGMS Cystic Fibrosis (CF) Carrier Testing in Primary Care: Bitesize resources and Toolkit – Click HERE

OUR PAGE ON LINKEDIN: www.linkedin.com/company/primarycareuk

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CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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In this episode of the NHS News show, hosts Emma Borders and Simon discuss pressing issues in primary care and recent NHS developments, focusing on Health Secretary Wes Streeting's commitment to reform amidst funding disparities. They highlight the alarming trend of GP practices returning contracts due to unsustainable costs, which leaves many patients without care.
The conversation also addresses the challenges of integrating technology in patient care due to staff digital literacy gaps, and GPs' concerns regarding workload management amid potential industrial action. The episode ends on a positive note with high patient satisfaction rates from the GP survey, encouraging healthcare workers to focus on successful interactions while maintaining supportive communication within the community.

Emma is a senior nurse and Si is a Paramedic and Advanced Clinical Practitioner. Representing Primary Care UK, they discuss what these news headlines mean for us working in the front line.

If you want to add to these discussions, you can do so through out LinkedIn Community group: Primary Care Community: Share Your Attitude! | Groups | LinkedIn

Presented by Emma Borders and Simon Robinson.

OUR PAGE ON LINKEDIN: www.linkedin.com/company/primarycareuk

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JOIN THE PRIMARY CARE COMMUNITY! bit.ly/4dHGtP4

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CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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IN THIS FIFTH EPISODE of Primary Care UK's six-part series on genomics, hosts Claire and Munir are joined by Anwar Khan and Sophia Varadkar to discuss the significance of rare diseases in the realm of primary care. The episode emphasizes the prevalence and impact of rare diseases, elaborating on how genomics can provide crucial insights for early diagnosis, treatment, and family counselling.

The discussion covers the importance of genetic testing, the role of primary care professionals in identifying and managing rare conditions, and the broader implications of equitable access to genetic services.

Special thanks to our guest speakers:

Dr Sophia Varadkar. Co-Medical Director North Thames Genomic Medicine Service, Deputy Medical Director and Consultant Paediatric Neurologist, Great Ormond St Hospital for Children NHS Foundation Trust, London

Dr Anwar Khan. GP with a Special Interest in Genomics.

SPONSOR: The Genomics mini-series was sponsored by, and co-produced with the North Thames Genomics Medicine Service

Useful links:

• National Genomics Education Programme – Knowledge Hub – What is rare disease? Click HERE
• National Genomics Education Programme – Primary Care - Presentation: Patient with a family history of sudden cardiac death. Click HERE
• National Genomics Education Programme – Knowledge Hub – The Generation Study. Click HERE
• NHS Race and Health Observatory - Ethnic inequities in genomics and precision medicine review report. Click HERE

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CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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THIS EPISODE is about Cultural Awareness. Irina Varlan speaks to two clinicians who have an interest in this area, as they cover important issues such as:

1. How to approach culure conversations, and what language to use when discussing.
2. Important principles to bear in mind.
3. By way of example, there will be a focus on Muslim patients fasting in Ramadhan.
4. And a vareity of other points worth knowing about different cultures and approaches we can use

Special thanks to our guest speakers:

• Dr Margaret Abbott, Health inequality lead for Nottingham City & GP;
• Farheen Jessa- was a Psych pharmacist at Notts HC trust with an interest in the stigma attached to mental health in the Asian community.

Useful links:

• Elearning for health Cultural awareness training modules: https://portal.e-lfh.org.uk/Component/Details/438885
• Government Migrant Health website: Migrant health guide - GOV.UK (www.gov.uk)
• Diabetes Uk Diabetes and Ramadan | Fasting | Diabetes UK
• BMJ infographic about things to consider in Ramadan (not just diabetes) Ramadan fasting with existing conditions | The BMJ
• British Islamic Medical Association advice on various topics: Advice | British Islamic Medical Association (britishima.org)

OUR PAGE ON LINKEDIN: www.linkedin.com/company/primarycareuk

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CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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THIS EPISODE: Do you agree there is more that needs doing to detect cancer early, and to treat optimally?

This is episode 4 of the 6-part Genomics mini-series, and looks at:

• Cancer and the role of Primary Care in early diagnosis/detection
• Using Breast cancer & Lung cancer genomics as examples
• Highlighting what you, the primary care clinician can do
• How genomics helps, not only for diagnosis, but in several other ways.

If you work in primary care and patients consult you, and you want cancer diagnosis and survival to improve, you should listen to this episode.

SPECIAL THANKS to our guest speakers:

Dr Angela George, North Thames Genomic Medicine Service Co-Medical Director, and Consultant Medical Oncologist and Consultant in Oncogenetics at the Royal Marsden Hospital.

Dania Shoeb, GP Partner with a special interest in Genomics.

SPONSOR: The Genomics mini-series was sponsored by, and co-produced with the North Thames Genomics Medicine Service

USEFUL LINKS:

• North Thames Genomic Medicine Service – CLICK HERE
• The Royal Marsden NHS Foundation Trust Patient information library - Implications of alterations in BRCA1 and BRCA2 – CLICK HERE
• The NHS Jewish BRCA Testing Programme - Link correct at the time of publication – CLICK HERE
• The NHS Genomics Education Programme - Family History – CLICK HERE

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CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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IN THIS EPISODE, doctors Catherine Byrne and Rahul Mohan discuss the critical aspects of managing chronic kidney disease (CKD) in primary care. They explain: the definition, prevalence, and risk factors of CKD, highlighting its association with other conditions such as hypertension, diabetes, and cardiovascular diseases.

Led by podcast host Irina Varlan, the conversation covers the role of primary care in early detection, optimal management, and timely referral to secondary care. They also discuss the importance of lifestyle modifications and the advancements in CKD treatments, including the adoption of new medications like SGLT2 inhibitors and finerenone. The discussion emphasizes the need for accurate coding and record-keeping in primary care to ensure effective monitoring and improved patient outcomes. Finally, the episode provides insights into various resources available for patients to help them understand and manage their condition better.

SPECIAL THANKS TO GUEST SPEAKERS:
Catherine Byrne, kidney consultant in Nottingham City Hospital. CKD Midlands Renal Network Lead
Rahul Mohan, GP in Rushcliffe and GPwER in Diabetes and CVRM Medicine, Nottingham and Nottinghamshire ICB. Board member, national Executive Committee of Primary Care Diabetes Society and SAHF.

OUR PAGE ON LINKEDIN: www.linkedin.com/company/primarycareuk

USEFUL RESOURCES:
CKS link-https://cks.nice.org.uk/topics/chronic-kidney-disease/

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CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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Imagine you had a time-bomb inside your body ticking away... now imagine that your GP surgery had the ability to detect it and defuse it, but didn't. How would that make you feel?

Familial hypercholesterolaemia is common and dangerous without treatment, yet most cases remain undiagnosed. The condition highlights the key role that primary care plays in terms of genomics.

IN THIS EPISODE Claire and Munir speak with those who have a clear insight into FH as a genomics condition, what you working in primary care can and should do, and that it's really not that difficult.

There is also brief coverage of Cystic Fibrosis, which in fact is one of three conditions where primary care has direct access to genetics.

Special thanks to our guest speakers:

Dominic Studdart, specialist Genomics nurse
Anwar Khan, GP with special interest in Genomics.

SPONSOR: The Genomics series is sponsored by the North Thames Genomics Medicine Service.

Useful links: Genomics episode links (primarycareuk.org)

OUR PAGE ON LINKEDIN: www.linkedin.com/company/primarycareuk

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JOIN THE PRIMARY CARE COMMUNITY! bit.ly/4dHGtP4

RATE US & comment on Apple podcasts/ Spotify (our humble request).

CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.

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What you, as a primary care clinician should know about:
- Vaping
- The General Practice contract deal
- GPs getting abused.

Emma is a senior nurse and Si is a Paramedic and Advanced Clinical Practitioner. Representing Primary Care UK, they discuss what these news headlines mean for us working in the front line.

If you want to add to these discussions, you can do so through out LinkedIn Community group: Primary Care Community: Share Your Attitude! | Groups | LinkedIn

Presented by Emma Borders and Simon Robinson.

OUR PAGE ON LINKEDIN: www.linkedin.com/company/primarycareuk

transition sound, 3 messages, end music, disclaimer.

JOIN THE PRIMARY CARE COMMUNITY! bit.ly/4dHGtP4

RATE US & comment on Apple podcasts/ Spotify (our humble request).

CONTRIBUTE: To sponsor or contribute, do visit our website: www.primarycareuk.org

DISCLAIMER: This podcast is aimed at specified categories of clinical staff working in the UK, and the content provided is both time and location specific. The aim is to ensure information is accurate, up-to-date and comprehensive, but this is not guaranteed. Hosts, other contributors, and the organisations they represent do not accept liability for any actions, consequences or effects that result, directly or indirectly from the information provided.

Specifically, this podcast is NOT intended for use by the general public or patients and must not be used as a substitute for seeking appropriate medical or any other advice. Views expressed are the opinion of the speakers, is general advice only and should not be used as a substitute for seeking advice from a specialist. Healthcare professionals accessing information must use their own professional judgement, and accept full responsibility when interpreting the information and deciding how best to apply it, whether for the treatment of patients, or for other purposes.

(C)Therapeutic Reflections Limited.