Episodes

  • Postpartum Depression: Importance of Early and Effective Treatment

    Postpartum Depression: Importance of Early and Effective Treatment
    Nov 21 2024
    Drs. Clayton and Payne review the burden of PPD, highlighting the importance of early and effective treatment. They explore the impact of PPD on not only postpartum patients, but also on infants, families, and society as a whole.
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    11 mins
  • Screening and Diagnosis of Postpartum Depression

    Screening and Diagnosis of Postpartum Depression
    Nov 20 2024
    Drs. Clayton and Payne review strategies for the identification and diagnosis of PPD. They discuss screening, diagnostic criteria, and differential diagnosis, among other topics.
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    11 mins
  • What is the risk of rhabdomyolysis in patients taking both SGLT2 inhibitors and statins?

    What is the risk of rhabdomyolysis in patients taking both SGLT2 inhibitors and statins?
    Nov 19 2024
    In this podcast, a study from Ontario revealed that SGLT2 inhibitors, when combined with statins, were associated with a 25% lower risk of rhabdomyolysis compared to DPP4 inhibitors. A phase I trial at Washington University demonstrated promising outcomes for a neoantigen DNA vaccine aimed at preventing recurrence in triple-negative breast cancer (TNBC). Finally, intensive systolic blood pressure control in Chinese patients with type 2 diabetes and elevated cardiovascular risk significantly reduced major cardiovascular events compared to standard care.
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    5 mins
  • Postpartum Depression: The Treatment Landscape

    Postpartum Depression: The Treatment Landscape
    Nov 18 2024
    Drs. Payne and Clayton review in detail the management of patients with postpartum depression; discussing specific agents and classes of drugs, as well as nonpharmacological interventions and holistic and complementary approaches.
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    7 mins
  • Shifting the Paradigm: Biologics in the Management of Food Allergy

    Shifting the Paradigm: Biologics in the Management of Food Allergy
    Nov 15 2024
    Drs. Siri and Jacobs discuss the biological treatment of patients with food allergies, reviewing currently available options, combination with immunotherapy, and other emerging therapies.
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    9 mins
  • Case-Based Approach to a Patient With Food Allergy

    Case-Based Approach to a Patient With Food Allergy
    Nov 14 2024
    Drs. Siri and Jacobs discuss a typical case of a 4-year-old patient with peanut allergy, reviewing diagnostic and management strategies, as well as considerations such as age, IgE levels, oral food challenge, and current therapies.
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    12 mins
  • A Personalized Approach to Treating Patients With ANCA‑Associated Vasculitis

    A Personalized Approach to Treating Patients With ANCA‑Associated Vasculitis
    Nov 13 2024
    Michael Putman, MD, MSci and Zachary Wallace, MD, MSc discuss a personalized approach to managing the treatment of patients with ANCA-associated vasculitis, including the role of ANCA type and titers and their impact on flare risk and treatment decisions.
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    11 mins
  • Can starting a medication abortion before confirming an intrauterine pregnancy offer a safe, effective alternative to waiting?

    Can starting a medication abortion before confirming an intrauterine pregnancy offer a safe, effective alternative to waiting?
    Nov 12 2024
    NEJM reports on the safety of very early medication abortion, showing that initiating abortion medication before ultrasound confirmation is as effective and safe as the standard approach, reducing barriers in restricted settings. Another study highlighted the long-term survival impact of combining dabrafenib and trametinib for resected stage III melanoma patients with *BRAF* V600 mutations, noting a potential benefit for specific genetic profiles despite statistical limitations. Lastly, a Science study revealed that reduced sugar intake during the first thousand days of life significantly lowers the risk of diabetes and hypertension, emphasizing early intervention as a lifelong health measure.
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    4 mins