Brain Fables
The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them
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Brain Fables
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Narrated by:
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Roman Howell
About this listen
An estimated 80 million people live with a neurodegenerative disease, with this number expected to double by 2050. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. The time to rethink degenerative brain disorders has come.
With no biological boundaries between neurodegenerative diseases, illnesses such as Parkinson's and Alzheimer's result from a large spectrum of biological abnormalities, hampering effective treatment. Acclaimed neurologist Dr. Alberto Espay and Parkinson's advocate Benjamin Stecher present compelling evidence that these diseases should be targeted according to genetic and molecular signatures rather than clinical diagnoses. There is no Parkinson's or Alzheimer's, simply people with Parkinson's or Alzheimer's. An incredibly important story never before told, Brain Fables is a wakeup call to the scientific community and society, explaining why we have no effective disease-modifying treatments, and how we can get back on track.
©2020 Alberto Espay and Benjamin Stecher (P)2022 TantorListeners also enjoyed...
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- Length: 7 hrs and 48 mins
- Unabridged
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Overall4.5 out of 5 stars 52
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Performance4.5 out of 5 stars 42
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Story4.5 out of 5 stars 42
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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5 out of 5 stars
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Overall4.5 out of 5 stars 1,360
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Performance4.5 out of 5 stars 1,162
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Story4.5 out of 5 stars 1,161
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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5 out of 5 stars
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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Overall4.5 out of 5 stars 125
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Performance4 out of 5 stars 109
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Story4.5 out of 5 stars 107
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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5 out of 5 stars
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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Happy Accidents
- Serendipity in Major Medical Breakthroughs in the Twentieth Century
- By: Morton A. Meyers
- Narrated by: Richard Waterhouse
- Length: 12 hrs and 37 mins
- Unabridged
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Overall4.5 out of 5 stars 50
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Performance4 out of 5 stars 45
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Story4.5 out of 5 stars 44
Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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1 out of 5 stars
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Don't waste your money!
- By Amazon Customer on 03-20-16
By: Morton A. Meyers
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The Book of Why
- The New Science of Cause and Effect
- By: Judea Pearl, Dana Mackenzie
- Narrated by: Mel Foster
- Length: 15 hrs and 14 mins
- Unabridged
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Overall4.5 out of 5 stars 833
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Performance4.5 out of 5 stars 690
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Story4.5 out of 5 stars 688
"Correlation does not imply causation". This mantra has been invoked by scientists for decades and has led to a virtual prohibition on causal talk. But today, that taboo is dead. The causal revolution, sparked by Judea Pearl and his colleagues, has cut through a century of confusion and placed causality - the study of cause and effect - on a firm scientific basis.
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5 out of 5 stars
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Great book! Not a great audiobook.
- By rrwright on 05-30-18
By: Judea Pearl, and others
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Know This
- Today's Most Interesting and Important Scientific Ideas, Discoveries, and Developments
- By: John Brockman
- Narrated by: Gabra Zackman, Dan John Miller
- Length: 14 hrs and 39 mins
- Unabridged
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Overall4 out of 5 stars 232
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Performance4 out of 5 stars 204
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Story4 out of 5 stars 201
Scientific developments radically alter our understanding of the world. Whether it's technology, climate change, health research, or the latest revelations of neuroscience, physics, or psychology, science has, as Edge editor John Brockman says, "become a big story, if not the big story". In that spirit this new addition to Edge.org's fascinating series asks a powerful and provocative question: What do you consider the most interesting and important recent scientific news?
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1 out of 5 stars
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Pete and Repeat and Re-repeat
- By Daniel L on 02-25-18
By: John Brockman
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Drugged: The Science and Culture Behind Psychotropic Drugs
- By: Richard J. Miller
- Narrated by: Roger Clark
- Length: 15 hrs and 42 mins
- Unabridged
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Overall4 out of 5 stars 359
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Performance4 out of 5 stars 317
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Story4 out of 5 stars 316
In Drugged, Miller takes listeners on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture. Drugged brims with surprises, revealing the fact that antidepressant drugs evolved from rocket fuel, highlighting the role of hallucinogens in the history of religion, and asking whether Prozac can help depressed cats. Entertaining and authoritative, Drugged is a truly fascinating book.
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4 out of 5 stars
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Interesting reading but heavy on the biochemistry
- By Scott on 06-28-14
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The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
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Overall4.5 out of 5 stars 5,893
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Performance4.5 out of 5 stars 5,171
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Story4.5 out of 5 stars 5,124
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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5 out of 5 stars
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It's a Wonderful Book
- By JKC on 06-02-16
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- By: Leonardo Trasande MD MPP
- Narrated by: Leonardo Trasande MD MPP
- Length: 6 hrs and 44 mins
- Unabridged
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Overall4.5 out of 5 stars 45
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Performance4.5 out of 5 stars 38
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Story4.5 out of 5 stars 38
Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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5 out of 5 stars
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The Must Read Book of 2019 is here early on Audio!
- By Ryan S on 12-21-18
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101 Theory Drive
- A Neuroscientist's Quest for Memory
- By: Terry McDermott
- Narrated by: Stephen Hoye
- Length: 8 hrs and 55 mins
- Unabridged
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Overall4 out of 5 stars 167
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Performance4 out of 5 stars 63
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Story4 out of 5 stars 65
It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.
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5 out of 5 stars
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Pretty Dang Funny
- By Will on 05-14-10
By: Terry McDermott
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The Ravenous Brain
- How the New Science of Consciousness Explains Our Insatiable Search for Meaning
- By: Daniel Bor
- Narrated by: Walter Dixon
- Length: 11 hrs and 15 mins
- Unabridged
-
Overall4 out of 5 stars 78
-
Performance4 out of 5 stars 74
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Story4 out of 5 stars 72
Consciousness is our gateway to experience: it enables us to recognize Van Gogh’s starry skies, be enraptured by Beethoven’s Fifth, and stand in awe of a snowcapped mountain. Yet consciousness is subjective, personal, and famously difficult to examine: philosophers have for centuries declared this mental entity so mysterious as to be impenetrable to science. In The Ravenous Brain, neuroscientist Daniel Bor departs sharply from this historical view, and proposes a new model for how consciousness works.
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4 out of 5 stars
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Effectively demystifies consciousness
- By Gary on 11-18-12
By: Daniel Bor
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The Spiritual Brain
- A Neuroscientist's Case for the Existence of the Soul
- By: Mario Beauregard, Denyse O'Leary
- Narrated by: Patrick Lawlor
- Length: 12 hrs and 50 mins
- Unabridged
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Overall3.5 out of 5 stars 162
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Performance4 out of 5 stars 89
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Story4 out of 5 stars 88
Does religious experience come from God, or is it just the random firing of neurons in the brain? Drawing on brain research on Carmelite nuns that has attracted major media attention and provocative new research in near-death experiences, The Spiritual Brain proves that genuine, life-changing spiritual events can be documented. The authors make a convincing case for what many in science are loathe to consider: that it is God who creates our spiritual experiences, not the brain.
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3 out of 5 stars
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interesting topic, but frustrating listen
- By Barry T on 08-27-08
By: Mario Beauregard, and others
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The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
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Overall5 out of 5 stars 4,689
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Performance5 out of 5 stars 4,110
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Story5 out of 5 stars 4,088
The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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5 out of 5 stars
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Incredible
- By S.R.E. on 03-02-16
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Doing Harm
- By: Maya Dusenbery
- Narrated by: Dara Rosenberg
- Length: 13 hrs and 33 mins
- Unabridged
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Overall4.5 out of 5 stars 159
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Performance4.5 out of 5 stars 138
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Story4.5 out of 5 stars 138
Editor of the award-winning site Feministing.com, Maya Dusenbery brings together scientific and sociological research, interviews with experts within and outside the medical establishment, and personal stories from women across the country to provide the first comprehensive, accessible look at how sexism in medicine harms women today.
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5 out of 5 stars
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One of the most important books ever written
- By Dresden on 03-18-18
By: Maya Dusenbery
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13 Things That Don't Make Sense
- The Most Baffling Scientific Mysteries of Our Time
- By: Michael Brooks
- Narrated by: James Adams
- Length: 8 hrs and 58 mins
- Unabridged
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Overall4 out of 5 stars 2,565
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Performance4 out of 5 stars 1,560
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Story4 out of 5 stars 1,564
Science starts to get interesting when things don't make sense. Science's best-kept secret is that there are experimental results and reliable data that the most brilliant scientists can neither explain nor dismiss. If history is any precedent, we should look to today's inexplicable results to forecast the future of science. Michael Brooks heads to the scientific frontier to meet 13 modern-day anomalies and discover tomorrow's breakthroughs.
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4 out of 5 stars
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10 interesting chapters-read epiloge first
- By Stephen on 06-10-09
By: Michael Brooks
What listeners say about Brain Fables
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall4 out of 5 stars
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Performance1 out of 5 stars
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Story4 out of 5 stars
- old_man_shakey
- 09-22-22
Great content. Insufferable narration.
I tried, I really did. But I'll be sitting down to finish this one, hard copy in hand. The narration was pretty much nails on the chalkboard for me. Very distracting over-the-top enunciation on Every. Single. Word.
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