An Elegant Defense
The Extraordinary New Science of the Immune System: A Tale in Four Lives
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An Elegant Defense
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Narrated by:
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Fred Sanders
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By:
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Matt Richtel
About this listen
A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.
“An Elegant Defense by Matt Richtel is one of those rare nonfiction books that transcends the genre. On one level it is a fascinating and engrossing account of the latest, and quite astonishing, discoveries involving the human immune system and how it works. But it is also a story about people facing mortality, about the passion of scientists searching for truth, and a meditation on death and how all of us struggle with the ultimate mystery. Heartfelt and moving, full of compassion, love, and the human drama, this is the work of a writer of high ethical character who is grappling with big issues and deep humanistic problems. What an inspiring and wonderful read. I highly recommend this extraordinary book.” (Douglas Preston, number-one best-selling author of The Lost City of the Monkey God)
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Very enlightening and information well supported
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By: Martin J. Blaser
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Plagues, Pandemics and Viruses
- From the Plague of Athens to COVID-19
- By: Heather E. Quinlan
- Narrated by: Samara Naeymi
- Length: 14 hrs and 28 mins
- Unabridged
-
Overall4 out of 5 stars 57
-
Performance4.5 out of 5 stars 47
-
Story4.5 out of 5 stars 47
It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.
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4 out of 5 stars
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Somewhat elemental
- By Bertha Watkins on 10-23-21
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Plague of Corruption
- Restoring Faith in the Promise of Science
- By: Dr. Judy Mikovits, Kent Heckenlively, Robert F. Kennedy Jr.
- Narrated by: Mariel Hemingway
- Length: 10 hrs and 10 mins
- Unabridged
-
Overall5 out of 5 stars 809
-
Performance4.5 out of 5 stars 722
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Story5 out of 5 stars 720
Dr. Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys' club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried.
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5 out of 5 stars
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If only most of the public knew these facts
- By David Getoff, CCN on 06-18-20
By: Dr. Judy Mikovits, and others
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Ten Drugs
- How Plants, Powders, and Pills Have Shaped the History of Medicine
- By: Thomas Hager
- Narrated by: Angelo Di Loreto
- Length: 8 hrs and 39 mins
- Unabridged
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Overall4.5 out of 5 stars 4,891
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Performance4.5 out of 5 stars 4,233
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Story4.5 out of 5 stars 4,215
Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.
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4 out of 5 stars
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Engrossing to physicians & lay persons alike
- By C. White on 03-08-19
By: Thomas Hager
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State of the Heart
- Exploring the History, Science, and Future of Cardiac Disease
- By: Haider Warraich
- Narrated by: Neil Shah
- Length: 11 hrs and 8 mins
- Unabridged
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Overall4.5 out of 5 stars 49
-
Performance5 out of 5 stars 41
-
Story4.5 out of 5 stars 40
In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease
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3 out of 5 stars
-
Good information, bad organization
- By Conor Cox on 09-03-19
By: Haider Warraich
-
An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
- Unabridged
-
Overall4.5 out of 5 stars 55
-
Performance4.5 out of 5 stars 48
-
Story4.5 out of 5 stars 49
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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5 out of 5 stars
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
-
p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
-
Overall4.5 out of 5 stars 125
-
Performance4 out of 5 stars 109
-
Story4.5 out of 5 stars 107
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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5 out of 5 stars
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
-
The Emperor of All Maladies
- A Biography of Cancer
- By: Siddhartha Mukherjee
- Narrated by: Fred Sanders
- Length: 22 hrs and 18 mins
- Unabridged
-
Overall5 out of 5 stars 4,692
-
Performance5 out of 5 stars 4,111
-
Story5 out of 5 stars 4,089
The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".
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5 out of 5 stars
-
Incredible
- By S.R.E. on 03-02-16
-
Happy Accidents
- Serendipity in Major Medical Breakthroughs in the Twentieth Century
- By: Morton A. Meyers
- Narrated by: Richard Waterhouse
- Length: 12 hrs and 37 mins
- Unabridged
-
Overall4.5 out of 5 stars 50
-
Performance4 out of 5 stars 45
-
Story4.5 out of 5 stars 44
Happy Accidents is a fascinating, entertaining, and highly accessible look at the surprising role serendipity has played in some of the most important medical discoveries in the 20th century. What do penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra have in common? They were each discovered accidentally, stumbled upon in the search for something else. In discussing medical breakthroughs, Dr. Morton Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science. And it may just save our lives!
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1 out of 5 stars
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Don't waste your money!
- By Amazon Customer on 03-20-16
By: Morton A. Meyers
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COVID: The Politics of Fear and the Power of Science
- By: Marc Siegel MD
- Narrated by: Peter Van Norden
- Length: 9 hrs and 19 mins
- Unabridged
-
Overall4.5 out of 5 stars 34
-
Performance4.5 out of 5 stars 31
-
Story4.5 out of 5 stars 32
COVID-19 has stolen our security and our nation's peace of mind. There is a pandemic virus as well as a crippling epidemic of fear sweeping America. Why? The answer, according to nationally renowned health commentator Dr. Marc Siegel, is that we already lived in an artificially created culture of fear that was just waiting to be unleashed. In COVID: The Politics of Fear and the Power of Science, Siegel identifies three major catalysts of the culture of fear - government, the media, and our own psyche.
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5 out of 5 stars
-
Informative and well sourced
- By A. Powers on 10-12-21
By: Marc Siegel MD
-
Evolving Ourselves
- How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth
- By: Juan Enriquez, Steve Gullans
- Narrated by: Rob Shapiro
- Length: 10 hrs and 50 mins
- Unabridged
-
Overall4.5 out of 5 stars 204
-
Performance4.5 out of 5 stars 178
-
Story4.5 out of 5 stars 181
Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?
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5 out of 5 stars
-
fascinating ideas and science
- By Joel on 07-04-15
By: Juan Enriquez, and others
-
The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
-
Overall4.5 out of 5 stars 52
-
Performance4.5 out of 5 stars 42
-
Story4.5 out of 5 stars 42
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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5 out of 5 stars
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
-
Less Medicine, More Health
- 7 Assumptions That Drive Too Much Medical Care
- By: H. Gilbert Welch
- Narrated by: L. J. Ganser
- Length: 8 hrs and 18 mins
- Unabridged
-
Overall5 out of 5 stars 102
-
Performance5 out of 5 stars 91
-
Story4.5 out of 5 stars 91
The author of the highly acclaimed Overdiagnosed describes seven widespread assumptions that encourage excessive, often ineffective, and sometimes harmful medical care. You might think the biggest problem in medical care is that it costs too much. Or that health insurance is too expensive, too uneven, too complicated - and gives you too many forms to fill out. But the central problem is that too much medical care has too little value.
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4 out of 5 stars
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The truth will set you free
- By Rene B Milner on 04-01-16
By: H. Gilbert Welch
-
The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- By: George Johnson
- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
- Unabridged
-
Overall4.5 out of 5 stars 62
-
Performance4.5 out of 5 stars 53
-
Story4.5 out of 5 stars 53
When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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5 out of 5 stars
-
A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
-
A Shot to Save the World
- The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine
- By: Gregory Zuckerman
- Narrated by: Jack Armstrong
- Length: 12 hrs and 6 mins
- Unabridged
-
Overall4.5 out of 5 stars 174
-
Performance4.5 out of 5 stars 147
-
Story4.5 out of 5 stars 146
Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization.
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5 out of 5 stars
-
Wow! Do not miss this one.
- By Jacob on 11-18-21
-
The Family That Couldn't Sleep
- A Medical Mystery
- By: D.T. Max
- Narrated by: Grover Gardner
- Length: 8 hrs and 45 mins
- Unabridged
-
Overall4 out of 5 stars 488
-
Performance4.5 out of 5 stars 270
-
Story4.5 out of 5 stars 273
For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.
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5 out of 5 stars
-
A great scientific mystery
- By David on 11-04-06
By: D.T. Max
-
The Language of Life
- DNA and the Revolution in Personalized Medicine
- By: Francis S. Collins
- Narrated by: Greg Itzin
- Length: 10 hrs and 45 mins
- Unabridged
-
Overall4 out of 5 stars 148
-
Performance4.5 out of 5 stars 99
-
Story4 out of 5 stars 97
A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
-
5 out of 5 stars
-
The future of medicine
- By Ronald E on 04-12-10
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In a rarified world of scientific research, a revolution has been brewing. Its activists are not anarchists, but rather Nobel Laureates in physics and economics and pony-tailed graduates, mathematicians, and computer scientists from all over the world. They have formed an iconoclastic think-tank and their radical idea is to create a new science: complexity. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell--and what the origin of life some four billion years ago can tell us about the process of technological innovation today.
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- Narrated by: Shannon Bream
- Length: 7 hrs and 26 mins
- Unabridged
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Overall5 out of 5 stars 54
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Performance5 out of 5 stars 51
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Story5 out of 5 stars 51
The Bible reveals not just butterflies and broken hearts. In Scripture, we see God’s beautiful design for the partnership of marriage. We witness friendships that cross all boundaries. We watch as families navigate the many seasons of life. Our guiding example for them all is the deepest, most abiding, foundational love ever known: God’s unconditional love for His people. In The Love Stories of the Bible Speak, Shannon Bream draws lessons from the good, the bad, and the ugly of Biblical romances, friendships, and families.
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5 out of 5 stars
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Uplifting and motivational book
- By Joseph Sullivan on 03-31-23
By: Shannon Bream
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Tickled
- A Commonsense Guide to the Present Moment
- By: Duff McDonald
- Narrated by: Sean Pratt
- Length: 9 hrs and 8 mins
- Unabridged
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Overall4.5 out of 5 stars 6
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Performance4.5 out of 5 stars 5
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Story4 out of 5 stars 6
A New York Times best-selling journalist sets out to explore our addiction to the quantification of everything and ends up confronting his own addiction to certainty. In the quiet of quarantine, he decides to choose ease, rather than control - pursuing habits and hobbies that bring joy and “tickles” to each and every moment - and finds peace of mind, renewed creativity, and deepened relationships are the reward.
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3 out of 5 stars
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It was just okay
- By AMCNYC on 11-10-21
By: Duff McDonald
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How the Mind Works
- By: Steven Pinker
- Narrated by: Mel Foster
- Length: 26 hrs and 5 mins
- Unabridged
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Overall4 out of 5 stars 1,622
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Performance4 out of 5 stars 1,322
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Story4 out of 5 stars 1,301
In this delightful, acclaimed bestseller, one of the world’s leading cognitive scientists tackles the workings of the human mind. What makes us rational—and why are we so often irrational? How do we see in three dimensions? What makes us happy, afraid, angry, disgusted, or sexually aroused? Why do we fall in love? And how do we grapple with the imponderables of morality, religion, and consciousness?
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4 out of 5 stars
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Excellent, but a difficult listen.
- By David Roseberry on 12-11-11
By: Steven Pinker
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Iron, Fire and Ice
- The Real History That Inspired Game of Thrones
- By: Ed West
- Narrated by: Rory Barnett
- Length: 20 hrs and 15 mins
- Unabridged
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Overall4.5 out of 5 stars 535
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Performance4.5 out of 5 stars 468
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Story4.5 out of 5 stars 463
A young pretender raises an army to take the throne. Learning of his father’s death, the adolescent, dashing and charismatic and descended from the old kings of the North, vows to avenge him. He is supported in this war by his mother, who has spirited away her two younger sons to safety. Against them is the queen, passionate, proud, and strong-willed and with more of the masculine virtues of the time than most men. She too is battling for the inheritance of her young son, not yet fully grown but already a sadist who takes delight in watching executions.
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5 out of 5 stars
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Fun history for all -not just Game of Thrones fans
- By Annabells on 06-14-19
By: Ed West
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The Art of Fear
- Why Conquering Fear Won't Work and What to Do Instead
- By: Kristen Ulmer
- Narrated by: Jane Oppenheimer
- Length: 11 hrs and 54 mins
- Unabridged
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Overall4.5 out of 5 stars 54
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Performance5 out of 5 stars 48
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Story4.5 out of 5 stars 47
We all feel fear. Yet we are often taught to ignore it, overcome it, push past it. But to what benefit? This is the essential question that guides Kristen Ulmer's remarkable exploration of our most misunderstood emotion in The Art of Fear. Once recognized as the best extreme skier in the world (an honor she held for 12 years), Ulmer knows fear well. In this conversation-changing audiobook, she argues that fear is not here to cause us problems.
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1 out of 5 stars
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Lacks efficacy and contradicts herself...hard no!
- By Julie Collins on 10-08-22
By: Kristen Ulmer
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Conflicted
- How Productive Disagreements Lead to Better Outcomes
- By: Ian Leslie
- Narrated by: Matthew Lloyd Davies
- Length: 7 hrs and 52 mins
- Unabridged
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Overall4.5 out of 5 stars 78
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Performance4.5 out of 5 stars 64
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Story4.5 out of 5 stars 63
In an increasingly polarized world, our only chance for coming together and moving forward is to learn from those who have mastered the art and science of disagreement. In this much-needed book, Ian Leslie explores what happens to us when we argue, why disagreement makes us stressed, and why we get angry. By drawing together the lessons he learns from different experts, he proposes a series of clear principles that we can all use to make our most difficult dialogues more productive—and our increasingly acrimonious world a better place.
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5 out of 5 stars
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One of the best books of the year
- By chris boutte on 03-19-21
By: Ian Leslie
What listeners say about An Elegant Defense
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Lauren
- 07-23-21
book of the year!
a story of life intermingled with the latest knowledge of the immune system: a book for those with no prior knowledge of medicine
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1 person found this helpful
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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- Kindle Customer
- 07-24-20
fascinating
a fascinating story
a great narration
an accurate science
a must for anyone who wants to learn about immunotherapy
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1 person found this helpful
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Quique G
- 08-10-20
Book of the year
The best science and health book I have ever read, with story, emotional sometimes, funny other times, very interesting. A must read for everybody
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Karan
- 09-10-21
Laymen’s way to immunology
Inspiring and quite an informational book on immunology. Simplified for someone who doesn’t have a background in biology
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1 person found this helpful
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Overall4 out of 5 stars
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Performance3 out of 5 stars
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Story5 out of 5 stars
- C. Brieant
- 05-07-19
Good science but too much biography
Very good discussion of the immune system. Could have done without the personal accounts. M
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Overall4 out of 5 stars
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Performance5 out of 5 stars
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Story3 out of 5 stars
- Erin Brewer
- 08-28-19
worth reading
interesting but could have done without the politicalization of the immune response. good reading and interesting information.
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3 people found this helpful
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Dutchgirl
- 03-19-19
Excellent
Loved this book. I think everyone should read it! He did an amazing job of explaining a complicated subject.
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1 person found this helpful
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Tater Tot
- 09-22-19
we all need to know this information
made me pay more attention to what I was eating and how to handle my everyday actions
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Ellen
- 03-30-19
Engrossing and well told
This is one of the most well written books I’ve heard. The narration was patient and well done. The book is not just an explanation of science - but an added perspective that, I think, made the book more relatable and important. HIGHLY RECOMMENDED
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Overall5 out of 5 stars
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Performance5 out of 5 stars
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Story5 out of 5 stars
- Rene Lans
- 06-21-21
Brilliant
It’s been a while that I simply could not put a book down. Refreshing and sobbing
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2 people found this helpful