• CAR T-cells, Interview with Dr Caroline Bateman
    Mar 14 2022
    CAR T-cell therapy is an exciting new treatment for acute leukaemia. In this episode, Dr Geoff interviews his colleague Dr Caroline Bateman about CAR T-cells and introducing the treatment option to her unit. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    46 mins
  • "S" is for "Special" : Stage MS Neuroblastoma (also called Stage IVS, 4S)
    May 20 2021
    There is a special subtype of neuroblastoma seen in very young children, with spread of disease throughout the body, but which needs a very different approach to treatment compared to older children with metastatic disease. This episode explains the features of this stage MS neuroblastoma, the early problems, and the treatment used. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    24 mins
  • Where did my child's immune system go?
    Mar 26 2021
    Childhood cancer treatment leads to severe impairment of the ability to fight infections. This episode explains what immune suppression means, what causes it, and the problems that result. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    45 mins
  • Update re the future of rock and roll.... CAR T-cells
    Mar 10 2021
    A few years ago I described CAR T-cells, but they weren't available for routine use. I now update things, with the very important news about CAR T-cell therapy now becoming available. There is also an interview with Dr Caroline Bateman re this subject in another episode. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    40 mins
  • Blood Cultures
    Mar 8 2021
    We take a lot of blood samples looking for infection in the bloodstream. This episode explains what blood cultures are all about. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    22 mins
  • PRISM, Molecular Profiling, and Informed Consent
    Feb 24 2021
    A number of countries have research studies where childhood cancers are analysed in great detail, testing all the DNA in something called 'molecular profiling'. The national Australian study of this is called PRISM, and it is a very exciting project. This episode explains a molecular profiling project and covers issues of obtaining informed consent from parents and patients as well. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    56 mins
  • The MEK inhibitors: trametinib and selumetinib
    Feb 19 2021
    The MEK inhibitors are a newer class of drug, and include trametinib, selumetinib and others. They have an important role in paediatric oncology, particularly in glioma treatment and in neurofibromatosis. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    41 mins
  • The needle in the haystack: Minimal Residual Disease
    Jan 14 2021
    Sophisticated techniques can detect one cancer cell amongst a million normal cells. This episode describes these methods and how they are used in treatment. Link to Patreon

    Hosted on Acast. See acast.com/privacy for more information.

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    42 mins