You’ve likely heard the headlines gushing about the weight loss effects of the GLP-1 agonist class of drugs, agents that go by names like Wegovy, Mounjaro, Rebelsus and others. Doctors are declaring these drugs as breakthroughs or even magical, witnessing the rapid and dramatic weight loss they can achieve.

People appear willing to accept the side-effects of nausea, vomiting, even bowel obstruction, a catastrophic complication, or thyroid cancer, or pancreatitis that can irreversibly damage your pancreas and make you a type 1 diabetic. They also accept the costs that vary widely, depending on who dispenses it, but not uncommonly hundreds of dollars, even over a thousand dollars a month. And doctors jump at the chance to prescribe these drugs, as they often have arrangements with the dispensing pharmacy for kickbacks in one form or another. Prescribe the drug, make a lot of money, for many doctors an irresistible temptation.

People lose weight and even can become non-type 2 diabetic and modestly reduce risk for heart disease—so what’s not to like?

Plenty. That is the topic of discussion today on the Defiant Health podcast, a place where you hear ideas you cannot hear anywhere else because we dig deeper, are not swayed by big payoffs, and thumb our nose at conventional wisdom. The GLP-1 agonist drugs are not miraculous, but invite health disaster or hold you hostage for the rest of your life, shelling out money to enrich the pharmaceutical industry and doctors.

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Books:

Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight

Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed