The world of anesthesia is evolving, and pain management is at the forefront of this transformation. In this episode, we dive into the revolutionary non-opioid analgesic, Suzetrigine, a selective NaV1.8 inhibitor making waves in perioperative and acute pain management. With increasing pressure to reduce opioid dependence while maintaining effective pain control, anesthesia providers must stay ahead of cutting-edge developments. Join us as we break down the pharmacology, safety profile, clinical trial data, and real-world implications of this game-changing drug.

Here’s some of what we discuss in this episode:

• We’ll talk about dosing in extreme detail because, as anesthesia providers, we know that precision matters.
• The drug interactions is a critical consideration and we’ll run through adjustments that need to be made.
• We get to the into the physiology and pharmacology implications of Suzetrigine, focusing on what this means for nurse anesthetists.
• The pharmacological properties of Suzetrigine and how it functions at a molecular level to modulate pain perception.
• The side effects and contraindications.
• Scientific trials and comparisons to other analgesics for nurse anesthetists.

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