Episodes

  • Introduction to Dealing with Non-proportional Hazards

    Introduction to Dealing with Non-proportional Hazards
    Nov 25 2024
    43 mins
  • How Real Leaders Help Their People Grow Professionally and As a Person

    How Real Leaders Help Their People Grow Professionally and As a Person
    Nov 18 2024
    Introduction to Episode: "How Real Leaders Help Their People Grow Professionally and Personally" What does it take to be a great leader? How do you build trust, inspire growth, and create real value for your team and organization? In this episode of The Effective Statistician, I sit down with Aziza Yormirzaeva and Klaus Breuer to answer these questions. Aziza shares how Klaus, her former manager, guided her to discover her passion for statistics and grow both as a professional and as a person. Klaus explains how he empowers his team, fosters trust, and creates a workplace culture that prioritizes learning and collaboration. Their story is filled with practical lessons, inspiring moments, and insights that will challenge how you think about leadership and personal growth. Let’s jump right into this fascinating conversation!
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    47 mins
  • Clinical Development of Gene Therapies

    Clinical Development of Gene Therapies
    Nov 11 2024
    What makes gene therapy so different from traditional drug development? How do we address safety when each patient only receives a single dose? And why are statisticians so essential in this process? In this episode of The Effective Statistician, I sit down with Oscar Segurado, an MD, PhD, an expert in gene and cell therapies, to answer these questions and more. Oscar draws on decades of experience in academia, med tech, and biopharma—including his work on the blockbuster drug Humira—to guide us through the complexities of clinical development in gene therapy. We discuss everything from early clinical trials to commercialization, uncovering the unique challenges of treating rare diseases like hemophilia A and spinal muscular atrophy. Whether you’re a statistician, data scientist, or just curious about the future of medicine, this episode offers valuable insights into the clinical development of gene therapies and the vital role statisticians play in advancing these groundbreaking treatments.
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    29 mins
  • Statistical Topics in Gene Therapy

    Statistical Topics in Gene Therapy
    Nov 4 2024
    What if we could target genetic diseases at their root, offering lifelong cures instead of temporary solutions? And what role do statisticians play in making this breakthrough possible? In this episode of The Effective Statistician, I dive into the fascinating world of gene therapy—an area packed with both promise and complexity. I'm thrilled to finally cover this revolutionary field with two expert guests, Avery McIntosh from Pfizer and Alex Sverdlov from Novartis. Together, we break down the science behind gene therapies, explore the ethical and logistical challenges, and reveal how statisticians drive these life-changing treatments forward. So, how close are we to curing diseases through gene therapy? Let’s jump in and find out.
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    43 mins
  • Clinical Development Plans

    Clinical Development Plans
    Oct 28 2024
    What does it take to create an effective clinical development plan? How do our early decisions shape the path of a compound through clinical phases? And how can statisticians actively balance the demands of science, speed, and cost in drug development? In this special 400th episode of The Effective Statistician, I dive into these questions with Carrie Li, a biostatistics expert whose career spans both big pharma and startups. Carrie shares how she builds clinical development plans from scratch, collaborates with cross-functional teams, and uses statistical expertise to create strategies that drive both scientific and commercial success. Join us as we explore the impact statisticians have on the clinical development journey.
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    36 mins
  • The Most Important Things You Need to Know About AI And ML

    The Most Important Things You Need to Know About AI And ML
    Oct 21 2024
    Have you wondered how large language models (LLMs) like ChatGPT are transforming the way we work? How can AI tools boost efficiency in statistics and pharmaceutical research? In this episode of The Effective Statistician, I talk with Pietro Mascheroni from Boehringer Ingelheim to answer these questions. Pietro, a physicist, shares how LLMs are being used in real-world applications, from simplifying document retrieval to enhancing data exploration and refining code. We dive into why it’s crucial to maintain human oversight, how AI can improve team communication, and the challenges in validating these models. If you're eager to learn how AI can revolutionize your work or help you stay ahead in this fast-paced field, tune in to this insightful episode!
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    45 mins
  • Can Statisticians Contribute to Moving Out of The Statistics Function?

    Can Statisticians Contribute to Moving Out of The Statistics Function?
    Oct 14 2024
    Are you a statistician looking to expand your career beyond the statistics department? Do you want to know how your data expertise and strategic thinking can open new doors? In this episode of The Effective Statistician podcast, I sit down with Swarna Khare, who made that leap and found success in strategic roles across the industry. We explore her journey, discussing how statisticians can leverage their skills to create a bigger impact outside of technical roles. If you're ready to take your career to the next level, this episode is packed with actionable insights to help you step beyond the statistics function and into new opportunities.
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    41 mins
  • How Notion Can Help You With Productivity

    How Notion Can Help You With Productivity
    Oct 7 2024
    Are you trying to boost your productivity and organize your tasks more efficiently? In this episode of The Effective Statistician, I talk with Taina Pereenniemi about how Notion can help you take control of your workflows. Taina shares how she transformed her own productivity by using Notion to manage tasks, projects, and collaboration all in one place. We dive into how you can start using Notion right away to simplify your work and personal life. Plus, get a preview of Taina’s upcoming workshop at the Effective Statistician conference, where she'll guide participants through setting up their own Notion systems.
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    33 mins