How do small biotech companies make strategic decisions with limited resources? This episode dives deep into the art of prioritization and outsourcing to achieve success.

Join us as we speak with Mark Melville, Vice President of CMC, Biologics at Cullinan Therapeutics, a seasoned biotech scientist with years of experience in both large and small biotech companies. Mark shares his invaluable insights on navigating the complexities of bioprocess development and outsourcing.

In this episode, we explore:

1. Discover the secrets to prioritizing projects for maximum impact
2. Leverage outsourcing for flexibility and expertise
3. Learn to build strong relationships with external vendors to ensure top-notch quality and regulatory compliance.

Connect with Mark Melville:

LinkedIn: https://www.linkedin.com/in/mark-melville-a9a43b2

Next Steps:

Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com

Are you navigating the complex world of bioprocess CMC development and manufacturing in a small biotech company?

Our latest episode is a must-listen! Join us as we sit down with Mark Melville, Vice President of CMC, Biologics at Cullinan Therapeutics, who shares invaluable insights on overcoming the unique challenges faced by small biotech firms.

In this episode, we explore:

1. The critical communication strategies needed for successful outsourcing to CDMOs.
2. How small biotechs can leverage their agility to make fast, impactful decisions.
3. The surprising benefits of wearing multiple hats and fostering cross-functional expertise.

Tune in to discover how mastering these areas can help your small biotech thrive and stay ahead in a competitive market.

Don't miss this opportunity to gain practical advice and turn your challenges into advantages!

Connect with Mark Melville:

LinkedIn: https://www.linkedin.com/in/mark-melville-a9a43b2

Next Steps:

Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com

In this insightful episode, we explore the cutting-edge field of glycoengineering and its transformative impact on biopharmaceutical drug design. Join us as we chat with Róisín O’Flaherty, Assistant Professor in the Department of Chemistry at Maynooth University, to uncover the nuances of chemoenzymatic glycogen engineering and its potential to revolutionize therapeutics.

Key Takeaways:

1. Understanding Glycoengineering: Discover the three main approaches—genetic, metabolomic, and chemoenzymatic—for modifying glycosylation and enhancing drug properties.
2. Real-World Applications: Learn how industry giants are leveraging glycoengineering to innovate cancer treatments and other therapies.
3. Future of Glycoanalytics: Explore how AI and machine learning are poised to further advance the precision and efficiency of glycoengineering.

Don't miss this deep dive into how glycoanalytics is paving the way for more effective and personalized biopharmaceutical drugs. Tune in to understand the future of drug design and the exciting possibilities it holds.

Connect with Róisín O’Flaherty:

LinkedIn: https://www.linkedin.com/in/roisin-o-flaherty-a67a2b8a

Twitter: https://x.com/irishglycogirl

Next Steps:

Book a free assessment to help you get started with glycoanalytics and glycoengineering at https://bruehlmann-consulting.com

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at hello@bruehlmann-consulting.com

Uncover the hidden science behind creating safer, more effective biological drugs! Dive into glycoanalytics and glycoengineering, the secret weapons revolutionizing biopharma.

Join us as we talk with Róisín O’Flaherty, Assistant Professor in the Department of Chemistry at Maynooth University, who breaks down the complexities of glycosylation and its pivotal role in drug development.

Key Takeaways:

1. Critical Quality Attributes: Understand how glycans influence the function and structure of biopharmaceutical products, enhancing their efficacy and safety.
2. Analytical Techniques: Learn about the three major approaches—native glycoprotein analysis, glycopeptide analysis, and released glycan analysis—each providing unique insights into glycosylation.
3. Future Trends: Discover how automation, AI, and advanced mass spectrometry are revolutionizing glycoanalytics, making it more accessible and precise.

Tune in to explore how glycoanalytics is driving the next generation of safer, more effective biopharmaceuticals!

Connect with Róisín O’Flaherty:

LinkedIn: https://www.linkedin.com/in/roisin-o-flaherty-a67a2b8a

Twitter: https://x.com/irishglycogirl

Next Steps:

Book a free assessment to help you get started with glycoanalytics and glycoengineering at https://bruehlmann-consulting.com

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at hello@bruehlmann-consulting.com

Join us as we explore the pivotal role of process mapping in biotech knowledge management. Our guest, Irwin Hirsh, a seasoned biotech consultant concentrating on enhancing business efficiency and effectiveness, shares invaluable insights into leveraging technology to streamline operations.

Key Insights:

1. Identifying Critical Process Knowledge: Learn strategies to identify and manage vital process knowledge essential for optimal performance.
2. Transitioning from Implicit to Explicit Knowledge: Discover why converting hidden, tribal wisdom into structured, accessible information is crucial for scalability and continuity.
3. Harnessing Digital Tools: Explore effective approaches to digital transformation, ensuring seamless integration and collaboration across teams and time zones.

Join us as Irwin uncovers actionable steps to enhance efficiency and innovation in biotech through strategic process mapping.

Connect with Irwin Hirsh:

LinkedIn: https://www.linkedin.com/in/ishirsh

Q-Specialists AB: https://www.qspecialists.com

Next Steps:

Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com

Want to turn your biotech chaos into streamlined success? Learn from expert Irwin Hirsh, a seasoned biotech consultant concentrating on enhancing business efficiency and effectiveness, on how process mapping can transform your knowledge management and elevate your business performance.

Key Takeaways:

1. Eliminate Scope Creep: Learn how to maintain focus in projects despite shifts and changes, improving productivity and reducing frustration.
2. Bridge Experience Gaps: Understand how process mapping creates a common language, enabling seamless knowledge transfer between seasoned experts and newcomers.
3. Enhance Systematic Approach: Discover the power of standardization and continuous improvement to boost overall business performance.

Tune in to uncover practical strategies that can transform your knowledge management practices and drive your biotech endeavors to new heights.

Connect with Irwin Hirsh:

LinkedIn: https://www.linkedin.com/in/ishirsh

Q-Specialists AB: https://www.qspecialists.com

Next Steps:

Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com

Get ready to dive into the fascinating world of cryopreservation!

In this episode, we welcome Mark Davison, an experienced entrepreneur and CEO of Grant Instruments, leaders in laboratory equipment, to explore the intricate science of freezing and thawing cells.

Mark brings his wealth of experience to demystify this crucial process, revealing how cutting-edge technology ensures precision and reliability in preserving biological samples.

Key Takeaways:

1. Mastering Precision: Learn how data acquisition and controlled rate freezing are essential to maintaining the integrity of your samples.
2. Technological Advancements: Discover the latest innovations transforming laboratory practices, from analog to digital conversions to remote monitoring.
3. Entrepreneurial Insights: Gain valuable advice on leveraging support systems and cultivating a collaborative culture to succeed in scientific entrepreneurship.

Tune in for an insightful conversation that blends technical expertise with practical advice, perfect for scientists and entrepreneurs alike!

Connect with Mark Davison:

LinkedIn: https://www.linkedin.com/in/markdavison100

The Big Experiment podcast: https://thebigexperiment.buzzsprout.com

Grant Instruments: https://www.grantinstruments.com

Next Steps:

Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com

Picture a world where we can freeze cells and bring them back to life perfectly intact.

In this episode, we're joined by Mark Davison, a leading expert in cryopreservation and CEO of Grant Instruments to uncover the intricate science of freezing and thawing cells. From basic principles to advanced techniques, we delve into how cryopreservation is revolutionizing biotechnology and cell therapies.

Key Takeaways:

1. Cell Survival Secrets: Discover why water is both a friend and foe in preserving cell viability, and how precise control over freezing rates can prevent cell damage.
2. Advanced Techniques: Learn about cutting-edge technologies that ensure safe and effective cryopreservation, minimizing risks associated with traditional methods like liquid nitrogen.
3. Automation in Cryopreservation: Understand the future of lab workflows with automation, reducing human error and increasing reproducibility in cell-based experiments.

Tune in to explore how cryopreservation is shaping the future of biotech!

Connect with Mark Davison:

LinkedIn: https://www.linkedin.com/in/markdavison100

The Big Experiment podcast: https://thebigexperiment.buzzsprout.com

Grant Instruments: https://www.grantinstruments.com

Next Steps:

Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment

Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com