Innovate and React

De: Kevin Hares
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  • Resumen

  • Talking about innovations in chemistry
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Ciencia Química
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Episodios
  • Is doing a PhD in worth it? From Brown Sludge to Breakthroughs

    Is doing a PhD in worth it? From Brown Sludge to Breakthroughs
    Apr 15 2025
    Are you thinking about pursuing a PhD in chemistry and have wondered if its with the struggle? In this episode of 'Innovate and React', we discuss the personal and professional journey of pursuing a PhD and share our motivations for studying chemistry. We discuss the challenges and surprises encountered during our PhD journey, and the important skills we developed through teaching and research. Every journey is different and depends on many different things. We give a glimpse into our experience with doing a PhD in chemistry and how it can be worth it.
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    38 m
  • Challenging HSAB: Reactive Molecules and Nucleophiles

    Challenging HSAB: Reactive Molecules and Nucleophiles
    Apr 1 2025
    In this episode of Innovate and React, I am talking with Justus Reitz, a chemist from TU Dortmund University, about the limitations of the HSAB (Hard and Soft Acids and Bases) concept in predicting reaction outcomes. We explore an alternative approach using the nucleophilicity scale developed by the Mayr group, which offers a more accurate prediction method. Justus shares insights from his PhD research on stabilizing highly reactive molecules, particularly the synthesis and stabilization of diazoalkenes. We discuss how the Mayr nucleophilicity scale can facilitate understanding and controlling chemical reactions, bridging the gap between theoretical concepts and practical applications. For more check out innovateandreact.com
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    44 m
  • Beyond Gold: Exploring Acid-Promoted Cyclization in Organic Chemistry

    Beyond Gold: Exploring Acid-Promoted Cyclization in Organic Chemistry
    Mar 18 2025
    How can we make pharmaceutical synthesis greener and more efficient? In this episode of Innovate and React, we dive into the world of organic chemistry with Dr. Nikolas Jankowski to explore an alternative to gold catalysis. While gold catalysts are known for their high selectivity and efficiency, their cost, environmental impact, and challenges in industrial applications call for new solutions. Nick shares his research on acid-promoted cyclization using hexafluoroisopropanol (HFIP) as a unique solvent, mimicking some of the effects of metal catalysts. We discuss the breakthroughs that led to a more efficient synthesis of oxazoles, molecules with promising pharmaceutical applications. Tune in as we uncover the intersection of fundamental research, reaction optimization, and the future of sustainable chemistry.
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    48 m
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