Nate Tice is joined by Charles McDonald as they look ahead to Week 10 of the NFL season by deep diving on the biggest matchup of the weekend and giving one thing to watch in every single game.

Nate and Charles start with the Detroit Lions taking on the Houston Texans on Sunday night, as it's hard to see how Houston can stop the Lions from dominating both sides of the ball, but Nate points out that having Joe Mixon on the field makes a big difference. Both predict a Lions win, but there is a scenario where C.J. Stroud can play enough hero ball to keep it close.

Next, Nate and Charles give one thing to watch for every Week 10 matchup as they get into the one interesting matchup in the Munich game, a big rookie quarterback battle, the Pope sending encouraging words to the New Orleans Saints, how Bo Nix can beat the Spagnuolo defense, Jayden Daniels vs. Mike Tomlin, how Aaron Rodgers will attack the Arizona defense and much more.

Nate finishes up with a mailbag question on the Los Angeles Chargers run game as he takes a closer look at the offense in its first year under Jim Harbaugh.

(4:35) Detroit Lions @ Houston Texans

(20:25) New York Giants @ Carolina Panthers

(26:10) New England Patriots @ Chicago Bears

(31:10) Atlanta Falcons @ New Orleans Saints

(34:55) Buffalo Bills @ Indianapolis Colts

(38:15) San Francisco 49ers @ Tampa Bay Buccaneers

(42:25) Denver Broncos @ Kansas City Chiefs

(47:30) Tennessee Titans @ Los Angeles Chargers

(51:20) Minnesota Vikings @ Jacksonville Jaguars

(53:15) Philadelphia Eagles @ Dallas Cowboys

(57:25) New York Jets @ Arizona Cardinals

(1:01:30) Pittsburgh Steelers @ Washington Commanders

(1:06:40) Miami Dolphins @ Los Angeles Rams

(1:12:20) What's wrong with the Chargers run game?

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Nate Tice is joined by Matt Harmon to give their instant reactions and analysis for every major trade after a wild NFL trade deadline before diving into their favorite (and least favorite) things they saw in Week 9 of NFL action.

The duo start off with the eight biggest trades from trade deadline day, as they give thumbs up or down on every transaction, including Marshon Lattimore to the Washington Commanders, Mike Williams to the Pittsburgh Steelers, Za'Darius Smith to the Detroit Lions, Jonathan Mingo to the Dallas Cowboys and more.

Later, Nate and Matt dive into their six favorite (and two least favorite) things they saw in Week 9. Matt highlights Liam Coen and the Tampa Bay Buccaneers, the New York Jets passing game and the Los Angeles Chargers defense, while Nate highlights the Detroit Lions, Bijan Robinson and the new faces showing up big on the Los Angeles Rams and Philadelphia Eagles defenses. Matt is upset about the Jermaine Burton saga, while Nate is flabbergasted at the Shane Waldron Chicago Bears offense.

(2:10) Trade deadline instant analysis: thumbs up or down

(32:45) Liam Coen is crushing it

(41:30) Lions are juggernauts

(49:05) Jets passing game came alive

(53:30) Bijan Robinson

(58:15) Chargers defense is scary

(1:05:15) New faces on Rams & Eagles defenses show up big

(1:12:10) Least favorite things from Week 9

Subscribe to Football 301 on your favorite podcast app:

🎧 Apple Podcasts: https://apple.co/46gILkF

🎧 Spotify: https://spoti.fi/3A4mYAD

📢Yahoo Sports podcast network: https://apple.co/3zEuT