• Current Treatment Approaches for Patients with Cold Agglutinin Disease

  • Aug 30 2021
  • Length: 8 mins
  • Podcast

Current Treatment Approaches for Patients with Cold Agglutinin Disease

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  • Summary

    • Treatment goals should be to improve anemia by increasing Hb levels, avoid transfusion, improve circulatory symptoms caused by cold temperatures and reduce inflammatory symptoms
    • There are a number of non-pharma treatment options, including thermal protection and cold avoidance and transfusions (avoid cold transfusions)
    • Corticosteroids should not be used to treat CAD
    • There are several first-line and second-line pharmaceutical treatment strategies, including Rituximab monotherapy, Rituximab-Bendamustine and Rituximab-Fludarabine combination therapies and Bortezomib monotherapy
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