What makes a good life? For decades, psychologists have debated whether true fulfillment comes from happiness—a life of comfort and joy—or meaning—a life of purpose and impact. But what if there's a third way?

University of Chicago psychology professor Shigehiro Oishi has spent his career studying happiness, meaning, and what truly brings people deep satisfaction. His new research suggests that some of the most fulfilled people don’t prioritize either—they live psychologically rich lives, full of novelty, challenges, and transformative experiences.

In this episode, Oishi explains why psychological richness might be the missing piece in our search for fulfillment.

Imagine a future in which Band-Aids talk to your cells, pacemakers are powered by light and your gut microbiome gets a tune-up—all thanks to tiny bioelectric devices. Sounds like sci-fi, right? Think again.

Prof. Bozhi Tian of the University of Chicago is on the frontier of bioelectronics, building living machines that can heal, enhance and maybe even transform what it means to be human. In this episode, he explains his research lab’s work and explores the thrilling, strange and sometimes unsettling world in which biology meets technology.

Five years after COVID became a global pandemic, could another health crisis be on our horizon? According to scientists who study diseases, the possibility of a fungal pandemic—the subject of science fiction TV shows like “The Last of Us,” could be more of a reality, thanks to climate change and our warming planet. As fungi are adapting to warmer climates, they are becoming increasingly stronger and more resistant against the drugs we have to fight them.

Arturo Casadevall is one of the scientists who is warning against fungi's powerful potential. He's a professor of microbiology and immunology at the Johns Hopkins’ Bloomberg School of Public Health and the author of the new book, What If Fungi Win? He explains why fungi are becoming a growing public health threat, and what tools we have to protect ourselves from a future fungal outbreak.