Episodes

  • Authentic Biochemistry Podcast. Alzheimer’s Disease coda. Dr Daniel J Guerra.04sept24

    Authentic Biochemistry Podcast. Alzheimer’s Disease coda. Dr Daniel J Guerra.04sept24
    Sep 5 2024

    Correction:

    In my lecture I incorrectly used the W single letter designation as representing tyrosine. I miss-spoke.

    W=tryptophan while Y=tyrosine.

    The WW domain discussion is important for specific protein:protein interactions wherein the tryptophan (W) residues (found in the beta1 and beta 3 folds) are separated by 20 -22 amino acids that contain certain tyrosine (Y) residues in the beta2 region which may become phosphorylated thus generating phosophotyrosine binding (PTB)domains that are recognized by other proteins.

    I apologize for the error.




    References

    Exp Biol Med (Maywood). 2015 Mar; 240(3):375–382

    Cellular Physiology and Biochemistry (2017) 41 (3): 1189–1198.

    PNAS 2022 Sep6;119(36):e2204069119

    Alzheimer's Research & Therapy.2024.volume 16, Article number: 144 Joel, B. 1977. Vienna [Strangers;lp]

    https://open.spotify.com/track/4U45aEWtQhrm8A5mxPaFZ7?si=240c0d811f164b7c

    Beethoven, LV. 1816. Seventh Symphony A major. Op92.

    https://open.spotify.com/album/2kDHEJxutXleLTNCctvgSB?si=qefvirqXSviiOqPmvWME7w


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    1 hr and 20 mins
  • Authentic Biochemistry Podcast Moment. Dr Daniel J Guerra. 03Sept24

    Authentic Biochemistry Podcast Moment. Dr Daniel J Guerra. 03Sept24
    Sep 4 2024

    References

    Guerra, DJ. 2024 Moment in time.

    Willy and Joe Chambers. 1966. "Time Has Come Today"

    https://youtu.be/hIqwzQ7g-Cc?si=H17GGSKbeEyNXuE6

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    6 mins
  • Authentic Biochemistry Podcast. Pharmacotherapeutic drug mechanisms and their molecular targets in AD. DJGPhD.02September24.

    Authentic Biochemistry Podcast. Pharmacotherapeutic drug mechanisms and their molecular targets in AD. DJGPhD.02September24.
    Sep 3 2024

    References

    ASN Neuro. 2024 16:1, 2371160

    Alzheimer's Research & Therapy.2024. volume 16, Article number: 144.

    Neurosci Res. 2008 Mar;86(4):744-54.

    Mozart, WA. 1775. Violin Concerti 3-5

    https://open.spotify.com/album/0QFZNXt8rfAeqZbDGiixxc?si=n3BJ4g3VSaWIlwl3iSmZPA

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    53 mins
  • Authentic Biochemistry Podcast. The Insulin Involvement in Kinase Cascade Expansion of Tau and A- β Pathology 01September 2024 Dr. Daniel J. Guerra

    Authentic Biochemistry Podcast. The Insulin Involvement in Kinase Cascade Expansion of Tau and A- β Pathology 01September 2024 Dr. Daniel J. Guerra
    Sep 2 2024

    References

    Mini-Reviews in Medicinal Chemistry. 2022, Vol. 22, .#22.

    Brain Research 2024.April 15. Vol.1829.article 148793

    Miller. S. 1968."Quicksilver Girl"

    https://open.spotify.com/track/1gXEKJBTx2sLhY3AWkG6tu?si=43c6fcd157e64f9d

    Bach, JS. 1735. The Italian Concerto & Partitas

    https://open.spotify.com/album/6Sbk3UQiGoIagydUA4URdi?si=rweGy9M1QBK3Y4ETha9rDw

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    53 mins
  • Authentic Biochemistry Podcast Sphingolipids and Kinase Modulatory Influences on AD Proteinopathies 30 August 2024 Dr. Daniel J. Guerra

    Authentic Biochemistry Podcast Sphingolipids and Kinase Modulatory Influences on AD Proteinopathies 30 August 2024 Dr. Daniel J. Guerra
    Aug 31 2024

    •ReferencesMini-Reviews in Medicinal Chemistry. 2022, Vol. 22, .#22.Brain Research 2024.April 15. Vol. 1829.article 148793Ann Clin Transl Neurol. 2020 Feb; 7(2): 160–168.Biber. 1676. Mystery Sonatas. Romenesca.https://open.spotify.com/album/525eA1aCikerrBhLbe29Ms?si=r1BohC3uTv2V_NbmeXAJng

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    1 hr and 1 min
  • Authentic Biochemistry Podcast Alzheimer's Disease Pathobiochemical Inception Involves Mitochondrial Dysfunction. Dr. Daniel J. Guerra.27.8.24.

    Authentic Biochemistry Podcast Alzheimer's Disease Pathobiochemical Inception Involves Mitochondrial Dysfunction. Dr. Daniel J. Guerra.27.8.24.
    Aug 27 2024

    References

    Brain Research 2024.April 15. Vol. 1829.article 148793


    John Kay, Jerry Edmonton , Nick St. Nicholas, Larry Byrom, 1969. Steppenwolf. Monster title cut.

    https://open.spotify.com/track/0UwWLG6L2vm1r1fd1QDHqy?si=6a73e4a6eacd4328

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    48 mins
  • Authentic Biochemistry Podcast. Primer; Nucleotide Biochemistry I DJGPhD.25.8.24

    Authentic Biochemistry Podcast. Primer; Nucleotide Biochemistry I DJGPhD.25.8.24
    Aug 26 2024

    References

    Guerra, DJ. 2024 Nucleotide Graduate lectures

    Hunter-Garcia 1970. "Attics of my Life" Grateful Dead [American Beauty, lp.]

    https://open.spotify.com/track/6WeLHc9eLjVJqOKhd97vaK?si=d93bcc38ba7d4bac

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    29 mins
  • Authentic Biochemistry PodcastIntermediary metabolism, epigenetics, and the endomembranous network surveil, ascertain, and deliver upon cellular event ontology Including AD pathology.DJGPhD.24.8.24

    Authentic Biochemistry PodcastIntermediary metabolism, epigenetics, and the endomembranous network surveil, ascertain, and deliver upon cellular event ontology Including AD pathology.DJGPhD.24.8.24
    Aug 25 2024

    References

    Free Radic Biol Med. 2021 Jul; 170: 59–69. Biomolecules.2021 Feb; 11(2): 195.

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    1 hr