Mapping Humanity
How Modern Genetics Is Changing Criminal Justice, Personalized Medicine, and Our Identities
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Mapping Humanity
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Narrated by:
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Peter Lerman
About this listen
Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA - but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain - and what might we give up in return?
Inside each of your cells is the nucleus, a small structure that contains all of the genetic information encoded by the DNA inside, your genome. Not long ago, the first human genome was sequenced at a cost of nearly $3 billion; now, this same test can be done for about $1,000. This new accessibility of genome sequence information creates huge potential for advances in how we understand and treat disease, among other things. It also raises significant concerns regarding ethics and personal privacy.
In Mapping Humanity, cellular biology expert Joshua Z. Rappoport provides a detailed look at how the explosion in genetic information as a result of cutting-edge technologies is changing our lives and our world. Throughout, he explores the societal, ethical, and economic impacts of this new era. Offering a framework for balancing the potential risks and benefits of genetic information technologies and genetic engineering, Mapping Humanity is an indispensable guide to navigating the possibilities and perils of our gene-centric future.
©2020 Joshua Z. Rappoport, PhD (P)2020 HighBridge, a division of Recorded BooksListeners also enjoyed...
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- Unabridged
-
Overall4.5 out of 5 stars 1,360
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Performance4.5 out of 5 stars 1,162
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Story4.5 out of 5 stars 1,161
Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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5 out of 5 stars
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- By: Rob DeSalle, Susan L. Perkins
- Narrated by: Stephen McLaughlin
- Length: 7 hrs and 25 mins
- Unabridged
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Overall4.5 out of 5 stars 36
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Performance4.5 out of 5 stars 35
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Story4.5 out of 5 stars 34
Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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5 out of 5 stars
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I learned so much from this book. I am happy.
- By Jonathan Miller on 09-08-18
By: Rob DeSalle, and others
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Evolving Ourselves
- How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth
- By: Juan Enriquez, Steve Gullans
- Narrated by: Rob Shapiro
- Length: 10 hrs and 50 mins
- Unabridged
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Overall4.5 out of 5 stars 204
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Performance4.5 out of 5 stars 178
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Story4.5 out of 5 stars 181
Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?
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5 out of 5 stars
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fascinating ideas and science
- By Joel on 07-04-15
By: Juan Enriquez, and others
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- By: Leonardo Trasande MD MPP
- Narrated by: Leonardo Trasande MD MPP
- Length: 6 hrs and 44 mins
- Unabridged
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Overall4.5 out of 5 stars 45
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Performance4.5 out of 5 stars 38
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Story4.5 out of 5 stars 38
Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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5 out of 5 stars
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The Must Read Book of 2019 is here early on Audio!
- By Ryan S on 12-21-18
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Overall4.5 out of 5 stars 52
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Performance4.5 out of 5 stars 42
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Story4.5 out of 5 stars 42
Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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5 out of 5 stars
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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Life Unfolding
- How the Human Body Creates Itself
- By: Jamie A. Davies
- Narrated by: Napoleon Ryan
- Length: 9 hrs and 56 mins
- Unabridged
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Overall4.5 out of 5 stars 113
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Performance4.5 out of 5 stars 101
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Story4.5 out of 5 stars 101
Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?
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3 out of 5 stars
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Fascinating Biology ; Distracting Narration
- By Tim on 03-01-15
By: Jamie A. Davies
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An Epidemic of Absence
- A New Way of Understanding Allergies and Autoimmune Diseases
- By: Moises Velasquez-Manoff
- Narrated by: Chris Sorensen
- Length: 17 hrs and 6 mins
- Unabridged
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Overall4.5 out of 5 stars 55
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Performance4.5 out of 5 stars 48
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Story4.5 out of 5 stars 49
An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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5 out of 5 stars
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
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The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
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Overall4.5 out of 5 stars 5,893
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Performance4.5 out of 5 stars 5,171
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Story4.5 out of 5 stars 5,124
The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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5 out of 5 stars
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It's a Wonderful Book
- By JKC on 06-02-16
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Human Errors
- A Panorama of Our Glitches, from Pointless Bones to Broken Genes
- By: Nathan H. Lents
- Narrated by: L.J. Ganser
- Length: 7 hrs and 54 mins
- Unabridged
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Overall4.5 out of 5 stars 2,267
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Performance4.5 out of 5 stars 1,994
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Story4.5 out of 5 stars 1,989
We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.
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4 out of 5 stars
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From Pointless Bones to Broken Genes to...Aliens?
- By Katy.LED on 12-04-18
By: Nathan H. Lents
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Missing Microbes
- How the Overuse of Antibiotics Is Fueling Our Modern Plagues
- By: Martin J. Blaser
- Narrated by: Patrick Lawlor
- Length: 8 hrs and 43 mins
- Unabridged
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Overall4.5 out of 5 stars 379
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Performance4.5 out of 5 stars 322
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Story4.5 out of 5 stars 324
In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.
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5 out of 5 stars
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Very enlightening and information well supported
- By James on 05-03-15
By: Martin J. Blaser
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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Overall4.5 out of 5 stars 125
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Performance4 out of 5 stars 109
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Story4.5 out of 5 stars 107
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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5 out of 5 stars
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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Creation
- How Science Is Reinventing Life Itself
- By: Adam Rutherford
- Narrated by: Walter Dixon
- Length: 6 hrs and 53 mins
- Unabridged
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Overall4 out of 5 stars 44
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Performance4 out of 5 stars 43
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Story4 out of 5 stars 43
What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.
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5 out of 5 stars
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The Goldilocks book on what is life
- By Gary on 07-11-13
By: Adam Rutherford
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Radiation
- What It Is, What You Need to Know
- By: Robert Peter Gale, Eric Lax
- Narrated by: Robert Fass
- Length: 7 hrs and 27 mins
- Unabridged
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Overall4.5 out of 5 stars 82
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Performance4.5 out of 5 stars 69
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Story4.5 out of 5 stars 68
The essential guide to radiation: the good, the bad, and the utterly fascinating, explained with unprecedented clarity. Earth, born in a nuclear explosion, is a radioactive planet; without radiation, life would not exist. And while radiation can be dangerous, it is also deeply misunderstood and often mistakenly feared. Now Robert Peter Gale, M.D. - the doctor to whom concerned governments turned in the wake of the Chernobyl and Fukushima - in collaboration with medical writer Eric Lax draws on an exceptional depth of knowledge to correct myths and establish facts.
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5 out of 5 stars
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A great and accessible introduction to the field o
- By Neuron on 04-12-13
By: Robert Peter Gale, and others
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The Vital Question
- Energy, Evolution, and the Origins of Complex Life
- By: Nick Lane
- Narrated by: Kevin Pariseau
- Length: 11 hrs and 27 mins
- Unabridged
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Overall4.5 out of 5 stars 1,176
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Performance4.5 out of 5 stars 1,041
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Story4.5 out of 5 stars 1,030
The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.
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4 out of 5 stars
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Ouch!
- By Mark on 06-24-16
By: Nick Lane
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Pandora's Seed
- The Unforeseen Cost of Civilization
- By: Spencer Wells
- Narrated by: Spencer Wells
- Length: 6 hrs and 40 mins
- Unabridged
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Overall4 out of 5 stars 169
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Performance4 out of 5 stars 68
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Story4 out of 5 stars 69
This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.
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3 out of 5 stars
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Short and unfocused, but often quite interesting.
- By Alan on 06-23-10
By: Spencer Wells
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Between Hope and Fear
- A History of Vaccines and Human Immunity
- By: Michael Kinch
- Narrated by: Mel Foster
- Length: 15 hrs and 59 mins
- Unabridged
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Overall4.5 out of 5 stars 40
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Performance4.5 out of 5 stars 36
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Story4.5 out of 5 stars 36
Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Michael Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent - and could easily be undone. Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.
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4 out of 5 stars
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Enjoyed
- By Minsi Zhang on 05-03-20
By: Michael Kinch