Joanna Moncrieff is a British psychiatrist, author and researcher who is a prominent and controversial voice in the research of depression.

Her 2002 study ‘The Serotonin Theory of Depression: A Systematic Umbrella Review of the Evidence’ concluded that there was no link between serotonin and depression, debunking the mainstream medical belief in antidepressants.

Moncrieff, whose research has drawn criticism from ‘Big pharma’ and support from fringe figures on the right, speaks to Krishnan Guru-Murthy in the latest episode of Ways to Change the World.

Produced by Silvia Maresca, Ka Yee Mak and Tom Gordon-Martin.

Pia Sinha worked in prisons for 24 years before being appointed CEO of the charity Prison Reform Trust and she describes herself as a "ridiculously optimistic" person, who believes the prisons can be made to work properly.

Sinha started her career in prison as a psychologist and went on to work in female, male prisons and institutions for young offenders. She was the governor at three prisons and later was responsible for all the women’s prisons in the country.

Sinha, who believes many of the prisoners in the UK should not be behind bars, speaks to Krishnan Guru-Murthy in the latest episode of Ways to Change the World.

Produced by Silvia Maresca, Ka Yee Mak and Tom Gordon-Martin.

Sustainability expert and professor Mike Berners-Lee argues that dishonesty in politics, business, and the media is one of the biggest barriers to tackling global crises like climate change, social inequality, and environmental destruction.

In this episode of Ways to Change the World, he talks to Krishnan Guru-Murthy about the need for a cultural shift where honesty is valued, and where deceit in public life carries real consequences. Without this, he warns, we risk making the world's biggest challenges even harder to solve.

Produced by Silvia Maresca, Ka Yee Mak, Tom Gordon-Martin.

Entrepreneur, investor, and former Dragon’s Den star Sara Davies has spent 20 years building businesses and helping others do the same. She started her company, Crafter’s Companion, while still at university and turned it into a global brand. But as she tells Krishnan Guru-Murthy, success isn’t just about strategy - it’s about mindset.

It’s a theme she explores in her latest book, The Six-Minute Entrepreneur, which distills the lessons of her own journey into advice for anyone looking to succeed.

In this episode of Ways to Change the World, she reflects on the challenges facing small businesses, what she’s learned from Dragon’s Den, and why the UK needs to celebrate its entrepreneurs more. As she steps away from the Den, she also shares what’s next for her and why she remains deeply passionate about backing businesses that make a difference.

Produced by Silvia Maresca and Ka Yee Mak.

Christo Grozev is a Bulgarian investigative journalist who has spent years tracking down Russian spies and is on Vladimir Putin’s wanted list.

Grozev’s open-source journalism exposed spies linked to the poisoning of Sergei and Yulia Skripal in 2018 and Alexei Navalny in 2020.

Now he is at the centre of his own sinister Kremlin plot, as a Bulgarian spy-ring was sent by Moscow to target him and planned to kidnap and kill him, before they were arrested and convicted in the UK.

He speaks to Krishnan Guru-Murthy in this episode of Ways to Change the World ahead of the streaming release of his new documentary ‘Kill List: Hunted by Putin’s Spies’ - which is available on Channel 4.

Produced by Silvia Maresca, Calum Fraser, Ka Yee Mak.

Misan Harriman went from picking up a camera for the first time aged 40, to becoming one of the most influential photographers of his generation.

In 2020, his images of the Black Lives Matter protests went viral, capturing a historic moment of resistance and solidarity. He was also commissioned by Meghan Markle to take her second pregnancy announcement portrait and made history as the first Black photographer to shoot the cover for British Vogue's acclaimed September issue

For Harriman, photography is more than an art form - it’s activism. In this episode of Ways to Change the World, he talks to Krishnan Guru-Murthy about using his platform to challenge injustice, why he believes media coverage of major global issues - including the Israel-Palestine conflict - can fuel division rather than understanding, and why he wants to inspire the next generation to make a difference..

Produced by Silvia Maresca.

Krishnan Guru-Murthy sits down with Jude Kelly, founder of the Women of the World (WOW) Foundation, to talk about the rise of traditional values in global politics, equitable education and the arts and whether the divine really is 'a bloke'.

Kelly, a theatre director and former artistic director of the Southbank centre in London, reflects on her experiences challenging entrenched patriarchal values while growing up as an Irish immigrant in England; how she feels our financial, legal and religious norms have placed men in charge of society and what to do about it; the recent resurgence of traditional values and strongman politics; and why community-driven change is the real key to creating a more just and equitable society.

Produced by Silvia Maresca.

Why are the rich getting even wealthier while the middle and working classes continue to struggle? Former top trader Gary Stevenson - the star behind popular YouTube channel Gary’s Economics - breaks down how wealth inequality is driving down living standards for the middle and working classes on this episode of Ways to Change the World.

He tells Krishnan Guru-Murthy how the rich grow their wealth through passive income and investments, while ordinary people fall into debt, and argues that low interest rates, tax policies, and government responses to crises like 2008 and COVID-19 have mainly benefited the wealthy, deepening the financial divide. And finally, he urges people to educate themselves and push for change before inequality spirals further out of control.

Produced by Silvia Maresca.