In this episode of the Long COVID Clinical Podcast, hosts Andrew Schamess and Anita Chopra discuss recent research on Long COVID at Ohio State University. They are joined by Dr. Amal Amer, a Professor of Microbial Infection and Immunity, and Dr. Heba Amer, who works in Dr. Amal's lab. Dr. Amal shares her personal experience with Long COVID and details her research on the inflammasome and caspase-4/11, proteins linked to severe inflammation and cognitive issues in Long COVID. The discussion highlights the relationship between these proteins and the inflammatory response, potential coagulopathy, and how this research could lead to new treatments. Dr. Heba Amer describes using an advanced behavioral testing system for mice to study cognitive dysfunctions related to Long COVID. The findings offer promising avenues for drug discovery and a deeper understanding of Long COVID's pathology. Additionally, future research plans and the importance of correlating mouse model data with human samples are discussed. The episode concludes with optimism about ongoing and future research efforts.

Edited and Produced by Christopher Chiu

This episode of the Long COVID Clinical Podcast, hosted by Drs. Anita Chopra, Tiffany Walker, Andrew Schamess, and Aaron Friedberg, features Dr. Andrew Ayers, a specialist in allergy and immunology. The discussion focuses on the immunological processes involved in long COVID, including immune dysregulation, immune deficiency, and the role of mast cell activation syndrome (MCAS). Dr. Ayers explains the complexities of the immune system's response to long COVID, potential treatments like high-dose antihistamines and other therapies, and the impact of COVID and vaccinations on immune reactions. He also delves into patient phenotypes, drug allergies, and the gut microbiome's influence on immune responses. The episode concludes with a comprehensive review of MCAS management strategies and emphasizes the challenges faced by clinicians treating long COVID.

Edited and Produced by Christopher Chiu

In this episode of the Long COVID Clinical Podcast, we engage with Dr. Iman Majd, an expert in integrative medicine, to discuss the complexities of long COVID. They explore various symptoms, including fatigue and brain fog, and delve into integrative approaches that combine conventional and alternative treatments. Dr. Majd emphasizes the importance of personalized care, the role of supplements and herbal remedies, and the significance of an anti-inflammatory diet. The conversation highlights the need for patience and collaboration between patients and healthcare providers in the journey towards recovery from long COVID.

Edited and Produced by Christopher Chiu