In this episode, Northwestern Medicine neuro-oncologist, Priya Kumthekar, MD, discusses her pioneering work in nanomedicine on an early clinical trial in individuals with the deadly brain cancer glioblastoma. The study showed an experimental spherical nucleic acid drug, developed by Northwestern University scientists, was able to penetrate the blood-brain barrier and trigger the death of tumor cells. This was the first time a nanotherapeutic has been shown to cross the blood-brain barrier. The study set a precedent at Northwestern University and has opened the door for similar studies and innovations to take place here.

Moving the chemical and energy industries away from fossil fuel consumption is going to require effective and sustainable energy solutions. Northwestern University’s Dayne Swearer says nanotechnology is positioned to help make such solutions a reality. An assistant professor of Chemistry and a member of the IIN, Swearer’s lab is actively engaged in pioneering efforts in plasmonic nanoparticles and groundbreaking applications in renewable energy. In this episode, he talks about projects underway in his lab and how climate change issues help motivate him to make a contribution to science that will help make the world a better place for tomorrow.

Northwestern University nanoscientist Nathan Gianneschi, PhD, has been fascinated by the interaction of the organic and the synthetic since the start of his career. His lab’s discoveries have led to the development of synthetic melanin and polymers that can mimic cells. In this episode, he shares more about the potential biomedical applications of his research, the interdisciplinary partnerships that make his work possible and where to look for the future of nanotechnology.